Fap - fibroblast activation protein, alpha Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 192203

Summary

Predicted to enable several functions, including Integrin binding activity; peptidase activity; and protein homodimerization activity. Predicted to be involved in several processes, including melanocyte apoptotic process; melanocyte proliferation; and negative regulation of cell proliferation involved in contact inhibition. Predicted to be located in several cellular components, including basal part of cell; cell surface; and lamellipodium. Predicted to be part of peptidase complex. Predicted to be active in plasma membrane. Orthologous to human FAP (fibroblast activation protein alpha). [provided by Alliance of Genome Resources, Apr 2022]

Fap Products (1)

mRNA Protein Name
NM_138850.1 NP_620205.1 prolyl endopeptidase FAP
Protein Preferred Names Protein Names

prolyl endopeptidase FAP

  • seprase

Recombinant Fap Proteins

Cat. No. Product Name Accession Purity
HY-P78622 FAP Protein, Rat (HEK293, His) A0A8I6AEN0 (L26-D761) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Phase
HY-P3392A Zilganersen sodium Inhibitor 91.43% Phase 3
HY-137331 Linofapib bentoxetan 99.02% Phase 2
HY-172317 AZD2389 Inhibitor 99.65% Phase 2
HY-147057A Rofapitide tetraxetan acetate / Phase 1
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99269 Sibrotuzumab 99.05% Phase 2

Pre-clinical Phase

Bioactive Molecules (76)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-147057 Rofapitide tetraxetan 99.89% Unkown
HY-128643 FAPI-4 99.47% Unkown
HY-100684 UAMC-1110 Inhibitor 99.51% Unkown
HY-101801 Ac-Gly-BoroPro 99.89% Unkown
HY-145983 Suc-Gly-Pro-AMC 99.85% Unkown
HY-147173 FAPI-74 99.84% Unkown
HY-153552A NH2-UAMC1110 TFA Inhibitor 99.98% Unkown
HY-145938 OncoFAP 99.77% Unkown
HY-P10944 Unlabeled FXX489 Ligand 99.25% Unkown
HY-160289 ARI-3144 Substrate 99.72% Unkown
HY-164725 FAPI-mFS Inhibitor 98.71% Unkown
HY-P10131 3BP-3940 99.49% Unkown
HY-164316 FT-FAPI-12_9 99.07% Unkown
HY-125366 ARI-3099 Inhibitor 99.95% Unkown
HY-47979 FAP-IN-2 Inhibitor 99.93% Unkown
HY-136641 NOTA-FAPI Inhibitor 99.66% Unkown
HY-P3441A 3BP-4089 TFA Inhibitor 99.27% Unkown
HY-D2363 DOTA.SA.FAPi TFA Inhibitor 99.26% Unkown
HY-P10945 FAP targeting peptide for FXX489 99.49% Unkown
HY-139401 FAPI-34 Ligand 98.04% Unkown
HY-161074 PNT6555 96.55% Unkown
HY-164364A DOTAGA.(SA.FAPi)2 TFA Inhibitor 97.51% Unkown
HY-47979A FAP-IN-2 TFA Inhibitor 99.92% Unkown
HY-177435 FAPI-800CW Inhibitor 99.40% Unkown
HY-175350 OncoFAP-GlyPro-MMAE Ligand 99.71% Unkown
HY-175613 DOTA-ALB-02 Ligand 99.71% Unkown
HY-153552 NH2-UAMC1110 Inhibitor 99.86% Unkown
HY-173374 DOTAGA-FAP-2286-ALB Inhibitor 99.29% Unkown
HY-P10945B Cys-FAP targeting peptide for FXX489 TFA 95.77% Unkown
HY-183513 L-Ala-BPA Substrate 98.0% Unkown
HY-128642 FAPI-2 98.94% Unkown
HY-164316A FT-FAPI-12_9 TFA 99.48% Unkown
HY-164567 SID 125240931 98.75% Unkown
HY-D2281 FAP Ligand 2 / Unkown
HY-159768A DOTAGA.Glu.(FAPi)2 Ligand / Unkown
HY-159934 QI-18 Inhibitor / Unkown
HY-175612 DOTA-ALB-01 Ligand / Unkown
HY-103323 Fas C-Terminal Tripeptide Inhibitor / Unkown
HY-148361 Fluorogen binding modulator-1 / Unkown
HY-164364B DOTAGA.(SA.FAPi)2 analogue TFA Inhibitor 99.38% Unkown
HY-175353 TriOncoFAP-GlyPro-MMAE / Unkown
HY-184826 FAP Ligand-4 Inhibitor / Unkown
HY-175322 FAPI-P8PN Inhibitor / Unkown
HY-182434 CL 118326 Antagonist / Unkown
HY-170779 DOTA-NI-FAPI-04 Inhibitor / Unkown
HY-177459 DOTA-2P(FAPI)2 Inhibitor / Unkown
HY-182272 FAP-IN-9 Inhibitor / Unkown
HY-P11602 DOTA-C1-FAP-2286 / Unkown
HY-P3392 Zilganersen 91.43% Unkown
HY-174421 FAPI-JNU Ligand / Unkown
HY-P11599 NOTA-SP2A-FAPT Ligand / Unkown
HY-177083 Faridoxorubicin Substrate / Unkown
HY-159771 FAP6-19 Ligand / Unkown
HY-128642A FAPI-2 TFA 99.40% Unkown
HY-172137 FAPI-FUSCC-07 Ligand / Unkown
HY-175685 FAP-IN-7 Inhibitor / Unkown
HY-158326 FAP-IN-4 Inhibitor / Unkown
HY-176958 OncoFAP-EN-DOTAGA Inhibitor / Unkown
HY-P3392C Zilganersen sodium scrambled negative control Inhibitor / Unkown
HY-146182 FSDD3I / Unkown
HY-146180 FSDD0I / Unkown
HY-175330 FAP-IN-6 Inhibitor / Unkown
HY-183796 GFAP/NF-κB/APOE/NLRP3-IN-1 Inhibitor / Unkown
HY-186190 I-FAPI-04 prodrug-1 Inhibitor / Unkown
HY-146181 FSDD1I / Unkown
HY-149860 FAP-IN-1 Inhibitor / Unkown
HY-P10945A Cys-FAP targeting peptide for FXX489 / Unkown
HY-173319 FAP-IN-5 Inhibitor / Unkown
HY-178981 FAP-IN-8 Inhibitor / Unkown
HY-182250 BR103354 Inhibitor / Unkown
HY-161262 SB03178 Inhibitor / Unkown
HY-P3441 3BP-4089 Inhibitor 99.27% Unkown
HY-181494 FAPI-X5 Inhibitor / Unkown
HY-181580 FAP Ligand 3 Ligand / Unkown
HY-163079 AlF-PD-FAPI / Unkown
HY-W668749 3BP-3580 Inhibitor / Unkown
Inhibitory Antibodies (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990245 Anti-Mouse FAP Antibody (73.3) Inhibitor 95.00% Unkown
HY-P991995 OMTX005 Inhibitor 98.44% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fap NCBI NCBI:2191