Mpo - myeloperoxidase Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 303413

Summary

Enables peroxidase activity. Involved in several processes, including response to food; response to gold nanoparticle; and response to lipopolysaccharide. Located in extracellular space. Used to study acute kidney failure. Biomarker of chronic obstructive pulmonary disease; cystitis; and renovascular hypertension. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease 1; cystic fibrosis; kidney failure (multiple); liver disease (multiple); and lung disease (multiple). Orthologous to human MPO (myeloperoxidase). [provided by Alliance of Genome Resources, Apr 2022]

Mpo Products (2)

mRNA Protein Name
NM_001401812.1 NP_001388741.1 myeloperoxidase precursor
NM_001401812.1 NP_001388741.1 myeloperoxidase precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables peroxidase activity IDA
IDA: Inferred from direct assay
12922978 RGD
Biological Process GO Annotation Evidence References Source
involved in response to food IEP
IEP: Inferred from expression pattern
15788232 RGD
involved in response to gold nanoparticle IEP
IEP: Inferred from expression pattern
23150627 RGD
involved in response to lipopolysaccharide IEP
IEP: Inferred from expression pattern
15788232 RGD
involved in response to mechanical stimulus IEP
IEP: Inferred from expression pattern
9518261 RGD
involved in response to oxidative stress IDA
IDA: Inferred from direct assay
12922978 RGD
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
7996547 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

myeloperoxidase

Orthologs Information

Species Symbol Source ID
Homo sapiens Mpo NCBI NCBI:4353