ABCG2 - ATP binding cassette subfamily G member 2 Gene

Also Known as BCRP

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding
Gene ID: 478472

About ABCG2

Primary_assembly 32: 11,496,586-11,573,345 reverse strand.ROS_Cfam_1.0:CM025131.1

This gene has 2 transcripts (splice variants), 137 orthologues and 4 paralogues.

ABCG2 Products (8)

mRNA Protein Name
XM_038444098.1 XP_038300026.1 broad substrate specificity ATP-binding cassette transporter ABCG2 isoform X2
XM_038444096.1 XP_038300024.1 broad substrate specificity ATP-binding cassette transporter ABCG2 isoform X2
XM_038444094.1 XP_038300022.1 broad substrate specificity ATP-binding cassette transporter ABCG2 isoform X2
XM_038444097.1 XP_038300025.1 broad substrate specificity ATP-binding cassette transporter ABCG2 isoform X2
XM_038444092.1 XP_038300020.1 broad substrate specificity ATP-binding cassette transporter ABCG2 isoform X2
XM_038444091.1 XP_038300019.1 broad substrate specificity ATP-binding cassette transporter ABCG2 isoform X1
XM_038444095.1 XP_038300023.1 broad substrate specificity ATP-binding cassette transporter ABCG2 isoform X2
XM_038444093.1 XP_038300021.1 broad substrate specificity ATP-binding cassette transporter ABCG2 isoform X2

ABCG2 Protein Structure

3a01204

3a01204: cl36780 (123 - 716)

  • 0
  • 200
  • 400
  • 600
  • 723 a.a.
Protein Preferred Names Protein Names

broad substrate specificity ATP-binding cassette transporter ABCG2

  • ATP binding cassette subfamily G member 2 (Junior blood group)

  • ATP-binding cassette protein G2

  • breast cancer resistance protein

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-10440 Vismodegib 99.97% Yes
HY-101561 Avapritinib Inhibitor 99.85% Yes
HY-109061 Lazertinib 99.87% Unkown

Clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-109019 Vorolanib Inhibitor 99.78% Phase 3
HY-101570 Nedisertib 99.70% Phase 2
HY-10527C Telatinib mesylate Inhibitor 99.74% Phase 2

Pre-clinical Phase

Bioactive Molecules (58)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-10010 Ko 143 Inhibitor 99.97% Unkown
HY-11079 A-803467 Inhibitor 99.69% Unkown
HY-N2143 Fumitremorgin C Inhibitor 99.92% Unkown
HY-101453 Ceefourin 1 Inhibitor 99.72% Unkown
HY-10873 N-Desethyl Sunitinib 99.81% Unkown
HY-12757 YHO-13177 Inhibitor 99.65% Unkown
HY-D2869 Ac-H-FluNox 99.88% Unkown
HY-109061B Lazertinib mesylate 99.85% Unkown
HY-12758 YHO-13351 Inhibitor 99.16% Unkown
HY-136450 Triclabendazole sulfoxide Inhibitor 98.34% Unkown
HY-18010 PCI 29732 Inhibitor 99.59% Unkown
HY-111678 ML230 Inhibitor 99.65% Unkown
HY-100933 MY-5445 Inhibitor 99.79% Unkown
HY-113805 MC70 Inhibitor 99.50% Unkown
HY-144305 KPH2f Inhibitor 99.22% Unkown
HY-112505 Efflux inhibitor-1 Inhibitor 98.0% Unkown
HY-151432 URAT1 inhibitor 3 Inhibitor 98.02% Unkown
HY-P5391 LL-37(17-32) Inhibitor 96.71% Unkown
HY-RS00077 ABCG2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W049875 Nitroxynil 98.92% Unkown
HY-183623 ProAlk01 Inducer / Unkown
HY-101570G Nedisertib (GMP) Inhibitor / Unkown
HY-109061A Lazertinib mesylate hydrate / Unkown
HY-118083 Pentamethoxymorin Inhibitor / Unkown
HY-121645 2,4-Dibromoestradiol / Unkown
HY-122416 6,8-Diprenylnaringenin Inhibitor / Unkown
HY-129301 CCTA-1523 Inhibitor / Unkown
HY-136450S Triclabendazole sulfoxide-d3 Inhibitor / Unkown
HY-136450S1 Triclabendazole sulfoxide-13C,d3 Inhibitor / Unkown
HY-13774 WK-X-34 Inhibitor / Unkown
HY-146676 UR-MB108 Inhibitor / Unkown
HY-155652 ABCG2-IN-1 Inhibitor / Unkown
HY-155653 ABCG2-IN-2 Inhibitor / Unkown
HY-156092 Antitumor photosensitizer-4 / Unkown
HY-168573 AZ99 Inhibitor / Unkown
HY-170396 ABCG2-IN-4 Inhibitor / Unkown
HY-174435 ABCB1/ABCG2-IN-1 Inhibitor / Unkown
HY-17648 MBL-II-141 Inhibitor / Unkown
HY-178100 PARP1-IN-45 Inhibitor / Unkown
HY-178386 ABCG2-IN-5 Inhibitor / Unkown
HY-181731S (R,S,R)-Altenuene-13C15 / Unkown
HY-181802 MRS8431 / Unkown
HY-181803 MRS8432 / Unkown
HY-181804 MRS8288 Inhibitor / Unkown
HY-182000 Xanthine oxidase-IN-23 / Unkown
HY-D3179 CDg13 Substrate / Unkown
HY-RS00078 Abcg2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS00079 Abcg2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W082856A Butein tetramethyl ether Inhibitor / Unkown
HY-119724 ABCG2-IN-3 Inhibitor / Unkown
HY-123526 NSC265473 / Unkown
HY-136450R Triclabendazole sulfoxide (Standard) Inhibitor / Unkown
HY-149469 3,7,2',4'-Tetramethoxy-5-hydroxyflavone Inhibitor / Unkown
HY-168572 MZ82 Inhibitor / Unkown
HY-N2651 5,7,3'-Trihydroxy-4'-Methoxy-8-prenylflavanone Inhibitor / Unkown
HY-W705354 Vismodegib-d4 / Unkown
HY-W716916 Vismodegib-d7 / Unkown
HY-W754911 Avapritinib-d3 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens ABCG2 NCBI NCBI:9429