2. Gene
  3. Hdac7 - histone deacetylase 7 Gene

Hdac7 - histone deacetylase 7 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Hdac7a

Gene ID: 84582 | Gene type: protein coding

About Hdac7

Primary_assembly 7: 128,923,920-128,962,072 reverse strand.mRatBN7.2:CM026980.1

This gene has 6 transcripts (splice variants), 263 orthologues, 12 paralogues and is associated with 3 phenotypes. Biased expression in Thymus (RPKM 193.5), Lung (RPKM 114.3) and 8 other tissues.

Summary

Predicted to enable several functions, including 14-3-3 protein binding activity; protein kinase C binding activity; and transcription corepressor activity. Involved in several processes, including cellular response to mechanical stimulus; negative regulation of neuron death; and neuron apoptotic process. Predicted to be located in cytosol and nucleus. Predicted to be part of histone deacetylase complex. Orthologous to human HDAC7 (histone deacetylase 7). [provided by Alliance of Genome Resources, Apr 2022]

Hdac7 Products(7)

mRNA Protein Name
XM_006242365.4 XP_006242427.2 histone deacetylase 7 isoform X2
XM_006242364.4 XP_006242426.2 histone deacetylase 7 isoform X1
XM_039080354.1 XP_038936282.1 histone deacetylase 7 isoform X1
XM_039080355.1 XP_038936283.1 histone deacetylase 7 isoform X6
XM_006242367.4 XP_006242429.2 histone deacetylase 7 isoform X5
XM_008765843.3 XP_008764065.1 histone deacetylase 7 isoform X4
XM_006242366.4 XP_006242428.2 histone deacetylase 7 isoform X3

Hdac7 Protein Structure

PHA03247

PHA03247: cl33720 (121 - 542)

Arginase_HDAC

Arginase_HDAC: cl17011 (543 - 918)

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  • 975 a.a.
Protein Preferred Names Protein Names

histone deacetylase 7

HD7

HD7a

histone deacetylase 7A

Related Agents

Approval
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-10221 Vorinostat Inhibitor 99.95% Yes
HY-13322 Pracinostat Inhibitor 99.82% Yes
Clinical Phase
Bioactive Molecules (9)
Cat. No. Product Name Effect
Purity Phase
HY-14842B Givinostat hydrochloride monohydrate Inhibitor ≥98.0% Phase 3
HY-14842 Givinostat Inhibitor 98.05% Phase 3
HY-14842A Givinostat hydrochloride Inhibitor / Phase 3
HY-16026 Ricolinostat Inhibitor 99.83% Phase 2
HY-15433 Quisinostat Inhibitor 98.34% Phase 2
HY-13522 Fimepinostat Inhibitor 99.95% Phase 2
HY-15433A Quisinostat dihydrochloride Inhibitor 98.28% Phase 2
HY-10223 CUDC-101 Inhibitor 99.19% Phase 1
HY-15994 Citarinostat Inhibitor 99.30% Phase 1
Pre-clinical Phase
Bioactive Molecules (22)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-18361 TMP195 Inhibitor 99.57% Unkown
HY-18360 TMP269 Inhibitor 98.05% Unkown
HY-13428 Tubacin Inhibitor 95.50% Unkown
HY-16699 Nexturastat A Inhibitor 99.03% Unkown
HY-115475 SW-100 Inhibitor 99.59% Unkown
HY-119939 CHDI-390576 Inhibitor 98.07% Unkown
HY-126330 SS-208 Inhibitor 99.00% Unkown
HY-149285 NT160 Inhibitor 99.58% Unkown
HY-117554 BRD9757 Inhibitor 99.75% Unkown
HY-146678 HDAC6-IN-5 Inhibitor / Unkown
HY-150109 Purinostat mesylate Inhibitor / Unkown
HY-146679 HDAC6-IN-6 Inhibitor / Unkown
HY-162319 Tubulin/HDAC-IN-4 Inhibitor / Unkown
HY-15144B (S)-Trichostatin A Inhibitor / Unkown
HY-150595 HDAC6-IN-10 Inhibitor / Unkown
HY-150774 HDAC6/HSP90-IN-2 Inhibitor / Unkown
HY-157740 XSJ-10 Inhibitor / Unkown
HY-149208 HDAC-IN-53 Inhibitor / Unkown
HY-152226 MC2590 Inhibitor / Unkown
HY-149283 JAK/HDAC-IN-2 Inhibitor / Unkown
HY-146684 HDAC-IN-36 Inhibitor / Unkown
HY-152225 MC2625 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hdac7 NCBI NCBI:51564