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HDAC3-IN-5

HDAC3-IN-5 (9c) is a HDAC3 selective inhibitor, with IC50 values of 4.2 nM, 1629 nM and 298.2 nM for HDAC3, HDAC2, HDAC1, respectively. HDAC3-IN-5 (9c) can effectively induce apoptosisin MV4-11 cells in vitro and reduce the expression of anti-apoptotic proteins, the development of HDAC3 selective inhibitors may serve as a potential lead compound to reverse Venetoclax resistance.

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  • CAS No.: 3095232-95-1
  • Formula: C28H38N4O
  • Molecular Weight:446.63
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    Please store the product under the recommended conditions in the Certificate of Analysis.

  • HDAC3-IN-5 Chemical Structure
    HDAC3-IN-5 Chemical Structure
CAS No.: 3095232-95-1
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All HDAC Isoforms

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  • HDAC3-IN-5 Chemical Structure
    HDAC3-IN-5 Chemical Structure
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  • HDAC3-IN-5