HDAC3-IN-6
HDAC3-IN-6 (Compound SC26) is a selective HDAC3 inhibitor with an IC50 of 53 nM. HDAC3-IN-6 dose-dependently induces the expression of PD-L1. HDAC3-IN-6 induces more pronounced Apoptosis and production of ROS. HDAC3-IN-6 exhibits high antitumor efficacy against colorectal cancer.
For research use only. We do not sell to patients.
- CAS No.: 3070532-72-5
- Formula: C23H23N5O3
- Molecular Weight:417.46
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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HDAC1 3.98 μM (IC50) |
HDAC3 53 nM (IC50) |
Chemical Information
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CAS No. 3070532-72-5
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Molecular Weight 417.46
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Formula C23H23N5O3
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SMILES
O=C(C1=CC=C(CNC(C2=CN=C(C3=CC=C4OC=CC4=C3)N2)=O)C=C1)NNCCC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HDAC3-IN-6 Related Classifications
HY-172133 Related Classifications
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