HDAC6-IN-59
HDAC6-IN-59 (Compound 38k) is a highly selective histone deacetylase 6 (HDAC6) inhibitor (IC50=3.12 nM, with 352-fold selectivity over HDAC1). HDAC6-IN-59 is promising for research of esophageal cancer.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 2998932-98-0
- Fòrmula: C22H18ClN5O2
- Peso molecular:419.86
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Descripciòn
IC50 & Target
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HDAC1 |
HDAC6 3.12 nM (IC50) |
Chemical Information
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No. CAS 2998932-98-0
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Peso molecular 419.86
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Fòrmula C22H18ClN5O2
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SMILES
O=C(C1=CC=C(CNC2=NC(C3=CC=C(C=C3)Cl)=NN2C4=CC=CC=C4)C=C1)NO
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocolo
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)