HRG038
HRG038 is a selective covalent BRD4 degrader. HRG038 binds covalently to the E3 ubiquitin ligase CUL4 DCAF16, recruiting it to BRD4, leading to the ubiquitination and subsequent proteasomal degradation of BRD4. HRG038 is promising for research of cancers.
For research use only. We do not sell to patients.
- Formula: C34H31Cl2N11O3S
- Molecular Weight:744.65
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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Molecular Weight 744.65
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Formula C34H31Cl2N11O3S
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SMILES
CC(N1C(S2)=C(C(C3=CC=C(Cl)C=C3)=N4)C(C)=C2C)=NN=C1[C@@H]4CC(N(CC5)CCN5C(/C=C/C(NC(C=N6)=CC(Cl)=C6N7N=CC=N7)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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