Aschantin
Aschantin, a bisepoxylignan, can be isolated from Magnolia biondii. Aschantin has antiplasmodial, Ca2+-antagonistic, platelet activating factor-antagonistic, and chemopreventive activities. Aschantin is a mTOR kinase inhibitor. Aschantin is also an inhibitor of Cytochrome P450 and UGT enzyme.
For research use only. We do not sell to patients.
- CAS No.: 13060-15-6
- Formula: C22H24O7
- Molecular Weight:400.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 13060-15-6
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Molecular Weight 400.42
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Formula C22H24O7
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SMILES
COC1=C(OC)C(OC)=CC([C@@H]2[C@]3([H])[C@@](CO2)([H])[C@@H](C4=CC=C(OCO5)C5=C4)OC3)=C1
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Lee CJ, et al. Aschantin targeting on the kinase domain of mammalian target of rapamycin suppresses epidermal growth factor-induced neoplastic cell transformation. Carcinogenesis. 2015 Oct;36(10):1223-34. [Content Brief]
[2]. Kwon SS, et al. Inhibitory Effects of Aschantin on Cytochrome P450 and Uridine 5'-diphospho-glucuronosyltransferase Enzyme Activities in Human Liver Microsomes. Molecules. 2016 Apr 27;21(5):554. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Aschantin Related Classifications
HY-N10754 Related Classifications
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