Emd - emerin Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25437

Summary

Predicted to enable actin binding activity and beta-tubulin binding activity. Involved in nuclear membrane reassembly. Located in nuclear envelope and spindle. Is integral component of membrane. Human ortholog(s) of this gene implicated in Emery-Dreifuss muscular dystrophy; X-linked Emery-Dreifuss muscular dystrophy 1; and dilated cardiomyopathy. Orthologous to human EMD (emerin). [provided by Alliance of Genome Resources, Apr 2022]

Emd Products (1)

mRNA Protein Name
NM_012948.2 NP_037080.2 emerin

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in nuclear membrane reassembly IEP
IEP: Inferred from expression pattern
10569247 RGD
Cellular Component GO Annotation Evidence References Source
located in nuclear envelope IDA
IDA: Inferred from direct assay
10569247 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

emerin

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (8)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-14721 Tepotinib 99.94% Yes
HY-14262 Vilazodone 99.73% Unkown
HY-14261 Vilazodone Hydrochloride 99.94% Unkown
HY-70057 Safinamide Inhibitor 99.86% Yes
HY-14771A Imeglimin hydrochloride 99.98% Unkown
HY-70057A Safinamide mesylate Inhibitor 99.07% Yes
HY-14771 Imeglimin 99.10% Unkown
HY-14721A Tepotinib hydrochloride / Unkown

Clinical Phase

Bioactive Molecules (16)
Cat. No. Product Name Effect
Purity Phase
HY-16141 Cilengitide 99.91% Phase 3
HY-100820 Sarizotan Agonist 98.23% Phase 3
HY-107384 Asimadoline Agonist 99.36% Phase 3
HY-100820B Sarizotan dihydrochloride Agonist / Phase 3
HY-106246 Pruvanserin Antagonist 99.54% Phase 2
HY-136280 Panamesine 99.54% Phase 2
HY-103115 Pruvanserin hydrochloride Antagonist / Phase 2
HY-106100 Roxindole / Phase 2
HY-133931 Bimakalim / Phase 2
HY-19273 Rimeporide Inhibitor 98.63% Phase 1
HY-15000 EMD534085 Inhibitor 99.55% Phase 1
HY-103410 Carmoxirole hydrochloride Agonist 99.82% Phase 1
HY-106844 EMD 53998 Inhibitor 99.59% Phase 1
HY-105112 Carmoxirole Agonist / Phase 1
HY-123356 EMD-503982 Inhibitor / Phase 1
HY-164394 EMD 1204831 Inhibitor / Phase 1
Inhibitory Antibodies (3)
Cat. No. Product Name Effect
Purity Phase
HY-P991214 Tucotuzumab celmoleukin 98.797% Phase 3
HY-P9969 Matuzumab 98.12% Phase 2
HY-P99183 Abituzumab Inhibitor 99.38% Phase 2

Pre-clinical Phase

Bioactive Molecules (43)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-15193 EMD638683 99.94% Unkown
HY-16143 Cilengitide TFA 99.92% Yes
HY-P0322 GRGDSPK Inhibitor 98.55% Unkown
HY-106844A (+)-EMD 57033 99.72% Unkown
HY-101473 EMD527040 Inhibitor 99.88% Unkown
HY-106100A Roxindole hydrochloride 99.48% Unkown
HY-107384A Asimadoline hydrochloride Agonist 99.57% Unkown
HY-106150B Eniporide hydrochloride Inhibitor 99.49% Unkown
HY-14203 (R)-Safinamide Inhibitor 99.89% Unkown
HY-107030 Nitrefazole 99.44% Unkown
HY-170410 EMD-95885 Antagonist 98.74% Unkown
HY-15193B EMD638683 (S-Form) Inhibitor 99.72% Unkown
HY-103130 EMD386088 Agonist 99.06% Unkown
HY-15193A EMD638683 (R-Form) Inhibitor 99.86% Unkown
HY-19134 EMD 56551 Agonist / Unkown
HY-70057S1 Safinamide-d4-1 Inhibitor 98.90% Unkown
HY-19273R Rimeporide (Standard) Inhibitor 98.11% Unkown
HY-100820A Sarizotan hydrochloride Agonist / Unkown
HY-101473A EMD527040 hydrochloride Antagonist / Unkown
HY-103130A EMD 386088 free base Agonist / Unkown
HY-103247 EMD 66684 Antagonist / Unkown
HY-103247B EMD-66684 potassium salt Antagonist / Unkown
HY-105539 EMD 86006 Inhibitor / Unkown
HY-106150A Eniporide mesylate Inhibitor / Unkown
HY-10777 EMD 495235 Inhibitor / Unkown
HY-114987 EMD 21657 Modulator / Unkown
HY-114990 EMD 57439 Inhibitor / Unkown
HY-14262S1 Vilazodone-d8 hydrochloride / Unkown
HY-169827 EMD-132338 Antagonist / Unkown
HY-175878 EMD-C02602 Modulator / Unkown
HY-A0300 Cyclopeptide-5 Antagonist / Unkown
HY-P0322A GRGDSPK TFA Inhibitor / Unkown
HY-P2075 EMD 55068 Antagonist / Unkown
HY-RS04345 EMD Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-106150 Eniporide Inhibitor / Unkown
HY-106472 Tioxaprofen Inhibitor / Unkown
HY-129714 EMD 52297 Inhibitor / Unkown
HY-14771S Imeglimin-d3 / Unkown
HY-19273A Rimeporide hydrochloride Inhibitor / Unkown
HY-70057S4 Safinamide-d5 Inhibitor / Unkown
HY-RS17358 Emd Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23812 Emd Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W705589 Rimeporide-15N3 hydrochloride Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Emd NCBI NCBI:2010