CQ-Mito
CQ-Mito is a Coumarin-Quinazolinone (CQ)-based derivative that targets mitochondria and exhibits profound phototherapeutic performances with an Phototoxic Index (PI) value of 167. CQ-Mito causes cell death by both apoptosis and ferroptosis. CQ-Mito mediates mitochondrial dysfunction, including mitochondrial morphology changed and the loss of MMP. CQ-Mito can efficiently inhibit the tumor growth in organoid tumor models.
For research use only. We do not sell to patients.
- Formula: C45H42BrN6O4P
- Molecular Weight:841.73
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 841.73
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Formula C45H42BrN6O4P
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SMILES
O=C(C(C1=NC2=CC=C(OCC3=CN(CCC[P+](C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6)N=N3)C=C2C(N1)=O)=C7)OC8=C7C=CC(N(CC)CC)=C8.[Br-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)