Chlamydocin (purity≥70%)
Chlamydocin (purity≥70%), a fungal metabolite, is a highly potent HDAC inhibitor, with an IC50 of 1.3 nM. Chlamydocin (purity≥70%) exhibits potent antiproliferative and anticancer activities. Chlamydocin (purity≥70%) induces apoptosis by activating caspase-3.
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- CAS 番号: 53342-16-8
- 分子式: C28H38N4O6
- 分子量:526.62
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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HDAC 1.3 nM (IC50) |
Chlamydocin (purity≥70%) is originally isolated from the fungus Diheterospora chlamydosporia. Chlamydocin (purity≥70%) exhibits a broad spectrum of antiproliferative activity toward various cancer cell lines, irrespective of their p53 status. The antiproliferative activity of Chlamydocin (purity≥70%) is accompanied by accumulation of hyperacetylated histones H3 and H4, induction of p21cip1/waf1, and accumulation of cells in G2/M phase of the cell cycle[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 53342-16-8
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分子量 526.62
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分子式 C28H38N4O6
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)