K-41
K-41 is an orally active antibiotic. K-41 can be obtained from Streptomyces hygroscopicus. K-41 has antibacterial and antiplasmodial activity.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 53026-37-2
- 分子式: C48H82O18
- 分子量:947.15
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
K-41 inhibits K1 and FCR3 strains of Plasmodium falciparum, with IC50s of 8.5 and 31 nM[1].
K-41 inhibits B. subtilis, B. anthracis, S. aureus, S. pyogenes, S. pneumonia, C. diphtheria, and M. tuberculosis, with MICs of 3.13, 1.56, 1.56, 0.78, 0.39, 0.78, and 3.13 µg/mL, respectively[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 53026-37-2
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分子量 947.15
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分子式 C48H82O18
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SMILES
C[C@H]([C@H]1OC)[C@](O[C@@H](C2)C[C@H](O[C@]3(O)[C@@H](O)C(O)=O)[C@@](C)([C@H]([C@@H]3C)OC)OC)([C@@H]([C@@H]2OC)C)O[C@@]1([C@]4([H])O[C@@]([C@]5([H])O[C@]([C@](O[C@@]6(O)C)([H])[C@H]([C@@H]([C@H]6C)O[C@@H](CC[C@@H]7OC)O[C@@H]7C)C)([H])CC5)([H])CC4)C
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Structure Classification
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Initial Source
germ
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Otoguro K, et al. In vitro and in vivo antimalarial activities of the monoglycoside polyether antibiotic, K-41 against drug resistant strains of Plasmodia. J Antibiot (Tokyo). 2002 Sep;55(9):832-4. [Content Brief]
[2]. Tsuji N, et al. Two new antibiotics, A-218 and K-41. Isolation and characterization. J Antibiot (Tokyo). 1976 Jan;29(1):10-4. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
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