Olanzapine-d3
Based on 1 Customer Validation
Olanzapine-d3 (LY170053-d3) is the deuterium labeled Olanzapine. Olanzapine is a selective, orally active monoaminergic antagonist with high affinity binding to serotonin H1, 5HT2A/2C, 5HT3, 5HT6 (Ki=7, 4, 11, 57, and 5 nM, respectively), dopamine D1-4 (Ki=11 to 31 nM), muscarinic M1-5 (Ki=1.9-25 nM), and adrenergic α1 receptors (Ki=19 nM). Olanzapine is an atypical antipsychotic.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.57%
- CAS 番号: 786686-79-1
- 分子式: C17H17D3N4S
- 分子量:315.45
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
5-HT Receptor アイソフォーム固有の製品をすべて表示
MoreDopamine Receptor アイソフォーム固有の製品をすべて表示
MoreAdrenergic Receptor アイソフォーム固有の製品をすべて表示
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生物活性
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D3 Receptor |
mAChR1 |
5-HT2A Receptor |
5-HT6 Receptor |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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CAS 番号 786686-79-1
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非標識Cas 132539-06-1
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性状 Solid
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分子量 315.45
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分子式 C17H17D3N4S
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Color White to yellow
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SMILES
[2H]C(N1CCN(C2=NC3=CC=CC=C3NC4=C2C=C(C)S4)CC1)([2H])[2H]
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別名
LY170053-d3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 20 mg/mL (63.40 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (277 KB)
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SDS (480 KB)
- English - EN (480 KB)
- Français - FR (480 KB)
- Deutsch - DE (480 KB)
- Norwegian - NO (480 KB)
- Español - ES (480 KB)
- Swedish - SV (480 KB)
- Italian - IT (480 KB)
- Korean - KR (480 KB)
- Portuguese - PT (480 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.1701 mL | 15.8504 mL | 31.7007 mL | 79.2519 mL |
| 5 mM | 0.6340 mL | 3.1701 mL | 6.3401 mL | 15.8504 mL | |
| 10 mM | 0.3170 mL | 1.5850 mL | 3.1701 mL | 7.9252 mL | |
| 15 mM | 0.2113 mL | 1.0567 mL | 2.1134 mL | 5.2835 mL | |
| 20 mM | 0.1585 mL | 0.7925 mL | 1.5850 mL | 3.9626 mL | |
| 25 mM | 0.1268 mL | 0.6340 mL | 1.2680 mL | 3.1701 mL | |
| 30 mM | 0.1057 mL | 0.5283 mL | 1.0567 mL | 2.6417 mL | |
| 40 mM | 0.0793 mL | 0.3963 mL | 0.7925 mL | 1.9813 mL | |
| 50 mM | 0.0634 mL | 0.3170 mL | 0.6340 mL | 1.5850 mL | |
| 60 mM | 0.0528 mL | 0.2642 mL | 0.5283 mL | 1.3209 mL |
Olanzapine-d3 関連分類
HY-14541S 関連分類
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