UNC4976 TFA
Based on 1 Customer Validation
UNC4976 TFA is a positive allosteric modulator (PAM) peptidomimetic of CBX7 chromodomain binding to nucleic acids. UNC4976 TFA simultaneously antagonizes H3K27me3-specific recruitment of CBX7 to target genes while increasing non-specific binding to DNA and RNA.
For research use only. We do not sell to patients.
- Purity: 95.59%
- Formula: C49H71F3N6O10
- Molecular Weight:961.12
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Histone Methyltransferase Isoforms
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Biological Activity
Chemical Information
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Appearance Solid
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Molecular Weight 961.12
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Formula C49H71F3N6O10
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Color White to off-white
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 50 mg/mL (52.02 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.0405 mL | 5.2023 mL | 10.4045 mL | 26.0113 mL |
| 5 mM | 0.2081 mL | 1.0405 mL | 2.0809 mL | 5.2023 mL | |
| 10 mM | 0.1040 mL | 0.5202 mL | 1.0405 mL | 2.6011 mL | |
| 15 mM | 0.0694 mL | 0.3468 mL | 0.6936 mL | 1.7341 mL | |
| 20 mM | 0.0520 mL | 0.2601 mL | 0.5202 mL | 1.3006 mL | |
| 25 mM | 0.0416 mL | 0.2081 mL | 0.4162 mL | 1.0405 mL | |
| 30 mM | 0.0347 mL | 0.1734 mL | 0.3468 mL | 0.8670 mL | |
| 40 mM | 0.0260 mL | 0.1301 mL | 0.2601 mL | 0.6503 mL | |
| 50 mM | 0.0208 mL | 0.1040 mL | 0.2081 mL | 0.5202 mL |
UNC4976 TFA Related Classifications
HY-126327A Related Classifications
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