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Cat. No.: HY-168453

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dBAZ2B

dBAZ2B is a BAZ2B PROTAC degrader, with a DC₅₀ of 19 nM. (Pink: BAZ2A/B ligand (HY-168449); Black: linker (HY-168450); Blue: VHL Ligand (HY-125905))
(Pink: BAZ2B ligand (HY-168449); Blue: VHL ligand (HY-125905); Black: linker (HY-168450)).

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 3104449-58-0
화학식: C₅₅H₆₆FN₁₁O₆S
분자량:1028.25

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

dBAZ2B Chemical Structure

CAS No.: 3104449-58-0

사이즈

가격

재고

수량

Amount: USD 0.00

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

dBAZ2B is a BAZ2B PROTAC degrader, with a DC₅₀ of 19 nM^[1]. (Pink: BAZ2A/B ligand (HY-168449); Black: linker (HY-168450); Blue: VHL Ligand (HY-125905)) (Pink: BAZ2B ligand (HY-168449); Blue: VHL ligand (HY-125905); Black: linker (HY-168450)).

All PROTACs Isoforms :

All Epigenetic Reader Domain Isoforms :

Chemical Information

CAS No. 3104449-58-0
분자량 1028.25
화학식 C₅₅H₆₆FN₁₁O₆S
SMILES

CC1=C(SC=N1)C2=CC(OC[C@@H]3CC[C@H](CC3)COCC4=NC(C5=CN(N=C5)C)=C(N4CCC6=CN(N=C6)C)C7=CC=C(C=C7)C#N)=C(C=C2)CNC([C@@H]8C[C@H](CN8C([C@H](C(C)(C)C)NC(C9(CC9)F)=O)=O)O)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Palaferri L, et al. Discovery of First-in-Class BAZ2A/B and BAZ2B-Selective Degraders. ACS Medicinal Chemistry Letters, 2025.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

상품명:
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수량:
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상품명:
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dBAZ2B

All PROTACs Isoforms

All Epigenetic Reader Domain Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

dBAZ2B Related Classifications

HY-168453 Related Classifications