PT3
Based on 1 Customer Validation
PT3 is a selective inhibitor of HDAC3 with an IC50 value of 0.25 μM. PT3 exhibits good brain penetration ability and bioavailability upon oral administration. PT3 can be used in the research of Alzheimer’s disease.
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- Purity: 99.94%
- CAS No.: 2710273-81-5
- 화학식: C18H17N5O
- 분자량:319.36
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
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Cell Cycle/DNA Damage Compound Library
HY-L004
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Epigenetics Compound Library
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Histone Modification Research Compound Library
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Anti-Alzheimer's Disease Compound Library
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Anti-Pancreatic Cancer Compound Library
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Neurodegenerative Disease-related Compound Library
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Lactylation Compound Library
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Biological Activity
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HDAC2 2.08 μM (IC50) |
HDAC1 1.05 μM (IC50) |
HDAC8 15 μM (IC50) |
Chemical Information
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CAS No. 2710273-81-5
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Appearance Solid
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분자량 319.36
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화학식 C18H17N5O
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Color White to off-white
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SMILES
O=C(C1=CN=C(NCC2=CC=CC=C2)C=N1)NC3=C(N)C=CC=C3
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
DMSO : 100 mg/mL (313.13 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.1313 mL | 15.6563 mL | 31.3126 mL | 78.2816 mL |
| 5 mM | 0.6263 mL | 3.1313 mL | 6.2625 mL | 15.6563 mL | |
| 10 mM | 0.3131 mL | 1.5656 mL | 3.1313 mL | 7.8282 mL | |
| 15 mM | 0.2088 mL | 1.0438 mL | 2.0875 mL | 5.2188 mL | |
| 20 mM | 0.1566 mL | 0.7828 mL | 1.5656 mL | 3.9141 mL | |
| 25 mM | 0.1253 mL | 0.6263 mL | 1.2525 mL | 3.1313 mL | |
| 30 mM | 0.1044 mL | 0.5219 mL | 1.0438 mL | 2.6094 mL | |
| 40 mM | 0.0783 mL | 0.3914 mL | 0.7828 mL | 1.9570 mL | |
| 50 mM | 0.0626 mL | 0.3131 mL | 0.6263 mL | 1.5656 mL | |
| 60 mM | 0.0522 mL | 0.2609 mL | 0.5219 mL | 1.3047 mL | |
| 80 mM | 0.0391 mL | 0.1957 mL | 0.3914 mL | 0.9785 mL | |
| 100 mM | 0.0313 mL | 0.1566 mL | 0.3131 mL | 0.7828 mL |
PT3 Related Classifications
HY-164782 Related Classifications
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