ZDLD13
ZDLD13, a β-carboline, is an orally active and selective CDK4/CycD3 inhibitor with an IC50 value of 0.38 μM. ZDLD13 exhibits potent anti-HCT116 activity including inhibition of colony formation, inhibition of invasion and migration, inducing of apoptosis, and arresting of G1 phase in cell cycle. ZDLD13 shows significant tumor growth inhibition in HCT116 tumor xenograft model.
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- CAS No.: 2762278-95-3
- 화학식: C18H14N4O
- 분자량:302.33
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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CDK4/CycD3 0.38 μM (IC50) |
Chemical Information
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CAS No. 2762278-95-3
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분자량 302.33
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화학식 C18H14N4O
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SMILES
O=C(C1=NC=CC2=C1NC3=C2C=CC=C3)NCC4=NC=CC=C4
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ZDLD13 Related Classifications
HY-115908 Related Classifications
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