Largazole thiol
Largazole thiol, the active form of Largazole (HY-13906), is a potent, selective and brain-penetrant class I HDAC inhibitor. Largazole thiol. Largazole thiol exerts antitumor and neuroprotective effects. Largazole thiol can be used for research of Glioblastoma.
For research use only. We do not sell to patients.
- CAS No.: 1132667-11-8
- Formula: C21H28N4O4S3
- Molecular Weight:496.67
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
5.9 nM
Compound: 2
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Antiproliferative activity against human HCT116 cells after 48 hrs in absence of DTT by MTT assay
Antiproliferative activity against human HCT116 cells after 48 hrs in absence of DTT by MTT assay
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[PMID: 25147612] |
Chemical Information
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CAS No. 1132667-11-8
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Molecular Weight 496.67
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Formula C21H28N4O4S3
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SMILES
C[C@@]12N=C(SC2)C3=CSC(CNC(C[C@H](OC([C@H](NC1=O)C(C)C)=O)/C=C/CCS)=O)=N3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Largazole thiol Related Classifications
HY-170890 Related Classifications
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