PROTAC BRD9 Degrader-5
PROTAC BRD9 Degrader-5 is a BRD9 PROTAC degrader. PROTAC BRD9 Degrader-5 is used in research on acute myeloid leukemia, rhabdoid tumor, synovial sarcoma, and multiple myeloma.
(Pink: BRD9 Target protein ligand; Blue: Cereblon E3 ligase ligand; Black: linker (HY-W129531)).
For research use only. We do not sell to patients.
- CAS No.: 2704616-86-2
- Formula: C39H42ClF3N6O4
- Molecular Weight:751.24
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All PROTACs Isoforms
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Biological Activity
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BRD9 |
PROTAC BRD9 Degrader-5 (Compound 83) exhibits extremely low degrading activity against BRD7 (BRD7 degradation IP/Emax >9990 nM/100%), and weak degrading activity against BRD4 (BRD4 degradation IP/Emax 1997 nM/81%)
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2704616-86-2
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Molecular Weight 751.24
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Formula C39H42ClF3N6O4
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SMILES
O=C1C2=C(C(C3=CC(OC)=C(CN4CCC(C5CCN(CC5)C6=CC=C(NC7C(NC(CC7)=O)=O)C=C6C(F)(F)F)CC4)C(Cl)=C3)=CN1C)C=CN=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)