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Cat. No.: HY-177729

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PROTAC BRD9 Degrader-9

PROTAC BRD9 Degrader-9 (Compound 16) is an efficient and selective targeting BRD9 PROTAC degrader. PROTAC BRD9 Degrader-9 does not cause significant cytotoxicity. PROTAC BRD9 Degrader-9 can be used for cancer research
(Pink: BRD9 ligand (HY-107446); Blue: Cereblon ligand (HY-W877239); Black: linker).

For research use only. We do not sell to patients.

Formula: C₄₁H₄₇N₇O₁₁
Molecular Weight:813.85

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

PROTAC BRD9 Degrader-9 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

PROTAC BRD9 Degrader-9 (Compound 16) is an efficient and selective targeting BRD9 PROTAC degrader. PROTAC BRD9 Degrader-9 does not cause significant cytotoxicity. PROTAC BRD9 Degrader-9 can be used for cancer research^[1] (Pink: BRD9 ligand (HY-107446); Blue: Cereblon ligand (HY-W877239); Black: linker).

IC₅₀ & Target^[1]

BRD9

All PROTACs Isoforms :

All Epigenetic Reader Domain Isoforms :

Chemical Information

Molecular Weight 813.85
Formula C₄₁H₄₇N₇O₁₁
SMILES

O=C(NCCOCCOCCNC1=CC=C(OC)C(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)CN(CC4=C(OC)C=C(C(C5=CC=NC=C65)=CN(C)C6=O)C=C4OC)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Bouguenina H, et al. A Degron Blocking Strategy Towards Improved CRL4CRBN Recruiting PROTAC Selectivity. Chembiochem. 2023 Dec 1;24(23):e202300351. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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PROTAC BRD9 Degrader-9

All PROTACs Isoforms

All Epigenetic Reader Domain Isoforms