58 Results for "

Gly-Pro

" in MedChemExpress (MCE) Product Catalog:
Products (58)

58 Results for "Gly-Pro" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-D1670
CAS No.: 68542-93-8
Z-Gly-Pro-AMC is a fluorogenic substrate. Z-Gly-Pro-AMC is hydrolyzed by prolyl endopeptidase to generate highly fluorescent 7-Amino-4-methylcoumarin (HY-D0027). (λex=380 nm, λem=465 nm) .
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3
3 Cited Publications
Cat. No.: HY-P0074
CAS No.: 67869-62-9
Synonyms: Gly-Pro-Arg-Pro; Pefa 6003
Target:  

Thrombin

Research Areas:  

Cardiovascular Disease

GPRP (Gly-Pro-Arg-Pro; Pefa 6003) is a fibrin polymerization inhibitor that inhibits the interaction between fibrinogen and the platelet membrane glycoprotein Ⅱb/IIIa complex (glycoprotein IIb/IIIa receptor) . GPRP increases the level of free thrombin in activated platelet-rich plasma by reducing the adsorption of thrombin onto fibrin. GPRP inhibits platelet aggregation and prolongs the thrombin-initiated clotting time in plasma. GPRP is applicable for research related to thrombosis and thrombotic diseases .
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3
3 Cited Publications
Cat. No.: HY-P0074A
CAS No.: 157009-81-9
Synonyms: Gly-Pro-Arg-Pro acetate; Pefa 6003 acetate
Target:  

Integrin

Research Areas:  

Cardiovascular Disease

GPRP acetate (Gly-Pro-Arg-Pro acetate) is a fibrin polymerization inhibitor that inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa) .
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2
2 Cited Publications
Cat. No.: HY-P4846
CAS No.: 292171-04-1
Ac-Pro-Gly-Pro-OH is an endogenous degradation product of extracellular collagen and acts as a CXCR2 agonist . Ac-Pro-Gly-Pro-OH exerts bactericidal activity by generating hydrogen peroxide, inhibits pulmonary inflammation, and reduces immune cell apoptosis (apoptosis). Ac-Pro-Gly-Pro-OH promotes the production of IFN-γ and inhibits the production of TNF-α and IL-6 in leukocytes. Ac-Pro-Gly-Pro-OH increases the survival rate of mice in sepsis models, enhances the bactericidal activity of neutrophils, acts as a neutrophil chemoattractant, induces neutrophil polarization, and regulates inflammatory and repair processes. Ac-Pro-Gly-Pro-OH induces chronic inflammation and tissue remodeling through sustained action. Ac-Pro-Gly-Pro-OH is released via alkaline hydrolysis of corneal proteins in alkali-injured eyes, thereby driving the early infiltration of neutrophils into the cornea. Ac-Pro-Gly-Pro-OH is applicable to research related to sepsis, chronic obstructive pulmonary disease, cystic fibrosis, bronchiolitis obliterans syndrome, severe asthma, idiopathic pulmonary fibrosis, and corneal ulcer .
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1
1 Cited Publications
Cat. No.: HY-W016887
CAS No.: 704-15-4
Synonyms: H-Gly-Pro-OH; Gly-Pro
Glycyl-L-proline (H-Gly-Pro-OH) is a dipeptide. Glycyl-L-proline can induce MCF-7 cells apoptosis. Glycyl-L-proline can enhance the inhibitory effect of the PRODH/POX knockout on collagen and DNA biosynthesis. Glycyl-L-proline can inhibit Gly-Sar and L-proline transport. Glycyl-L-proline can be used for the researches of cancer and metabolic disease, such as breast cancer .
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1
1 Cited Publications
Cat. No.: HY-145983
CAS No.: 80049-85-0
Purity:  99.16%
Research Areas:  

Cancer

Suc-Gly-Pro-AMC is a fluorescent substrate. Suc-Gly-Pro-AMC is a fibroblast activation protein (FAP) specific substrate. Suc-Gly-Pro-AMC reacts with recombinant porcine prolyl oligopeptidase. Suc-Gly-Pro-AMC can be used to study the activity of FAP, prolyl endopeptidase (PREP). Suc-Gly-Pro-AMC is used in glioma research .
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1
1 Cited Publications
Cat. No.: HY-137834
CAS No.: 115035-46-6
Purity:  98.68%
Gly-Pro-AMC hydrobromide is a fluorescent dye, it can be used as a specific fluorescent substrate for detecting Dipeptidyl peptidase IV (DPP-IV) activity .
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1
1 Cited Publications
Cat. No.: HY-P4217
CAS No.: 201928-42-9
Target:  

Cathepsin

Research Areas:  

Others

Z-Gly-Pro-Arg-AMC hydrochloride a fluorescent trypsin and cathepsin K substrate. Z-Gly-Pro-Arg-AMC hydrochloride can be used to determine trypsin and cathepsin K activity .
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Cat. No.: HY-A0299
CAS No.: 2239-67-0
Synonyms: Tripeptide 29
Target:  

MMP

Research Areas:  

Inflammation/Immunology

H-Gly-Pro-Hyp-OH is a collagen-derived peptide and also a dipeptidyl peptidase-4 inhibitor.\nH-Gly-Pro-Hyp-OH inhibits the activity of dipeptidyl peptidase-4 in vitro. H-Gly-Pro-Hyp-OH binds to the DNA-binding site of the JUN/FOS complex, blocks the formation of the DNA-JUN/FOS complex, and inhibits transcriptional activity. H-Gly-Pro-Hyp-OH is applicable to research related to skin photoaging, UVB-induced skin aging/photoaging, and thrombosis .
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Cat. No.: HY-119244
CAS No.: 103213-34-9
Purity:  99.92%
Target:  

Dipeptidyl Peptidase

Research Areas:  

Metabolic Disease

Gly-Pro-pNA hydrochloride is a chromogenic peptide substrate that can be cleaved by the circulating enzyme dipeptidyl peptidase IV (DPP IV). Gly-Pro-pNA hydrochloride is mainly used to detect the activity of aminopeptidases such as DPP IV. Gly-Pro-pNA hydrochloride can be investigated as an experimental antidiabetic agent .
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Cat. No.: HY-P2661
CAS No.: 78832-65-2
Research Areas:  

Infection

FA-Leu-Gly-Pro-Ala-OH is a furylacryloyl-terminal tetrapeptide that serves as a substrate for bacterial collagenase and spirochete metalloendopeptidase. FA-Leu-Gly-Pro-Ala-OH is specifically hydrolyzed by spirochete collagenase only at the Leu-Gly bond. FA-Leu-Gly-Pro-Ala-OH can be used to determine the equilibrium constant of peptide bond hydrolysis, and also to detect collagenase-mediated cleavage reactions via turbidimetry based on absorbance reduction .
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Cat. No.: HY-P4486
CAS No.: 7561-51-5
Synonyms: Pro-Gly-Pro
Target:  

Drug Derivative

Research Areas:  

Others

H-Pro-Gly-Pro-OH is a collagen-derived matrikine that has classically been described as a neutrophil chemoattractant. H-Pro-Gly-Pro-OH is perfectly positioned to focus neutrophils on the site required and direct a localized repair response. H-Pro-Gly-Pro-OH activates the transcription of neurotrophins and their receptor genes after cerebral ischemia .
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Cat. No.: HY-117483
CAS No.: 32302-76-4
Purity:  99.64%
Target:  

iGluR

Research Areas:  

Neurological Disease

Gly-Pro-Glu is a neuroactive peptide with a potent action on acetylcholine release. Gly-Pro-Glu is the N-terminal tripeptide of insulin-like growth factor-I. Gly-Pro-Glu inhibits glutamate binds to N-methyl-D-aspartate (NMDA) receptor with an IC50 value of 14.7 μM. Gly-Pro-Glu can be used for the research of neuroprotection .
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Cat. No.: HY-P4344
CAS No.: 1926163-52-1
Met-Gly-Pro-AMC is a fluorescent peptide substrate active against *Caenorhabditis elegans* DPF-3, hDPP4, and methionyl aminopeptidase 2 (MetAP2). Met-Gly-Pro-AMC undergoes cleavage via tripeptidyl peptidase activity to release a fluorescent product. Met-Gly-Pro-AMC is used to detect the activities of tripeptidyl peptidases and MetAP2 peptidases in in vitro enzyme activity assays .
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Cat. No.: HY-P4474
CAS No.: 17011-78-8
Target:  

Peptides

Research Areas:  

Others

Pz-Pro-Leu-Gly-Pro-d-Arg is a synthetic polypeptide substrate. Pz-Pro-Leu-Gly-Pro-d-Arg can be used to detect the collagenase-like activity of enzymes from various sources, such as Bacillus sp. AH-101 .
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Cat. No.: HY-P3827
CAS No.: 104914-40-1
Target:  

Peptides

Research Areas:  

Inflammation/Immunology

Cys-Gly-Tyr-Gly-Pro-Lys-Lys-Lys-Arg-Lys-Val-Gly-Gly is a13-mer synthetic peptide containing seven amino acids homologous to SV40 T antigen. Cys-Gly-Tyr-Gly-Pro-Lys-Lys-Lys-Arg-Lys-Val-Gly-Gly is capable of inducing nuclear transport .
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Cat. No.: HY-W016887R
CAS No.: 704-15-4
Synonyms: H-Gly-Pro-OH (Standard); Gly-Pro (Standard)
H-Gly-Pro-OH (Standard) is the analytical standard of H-Gly-Pro-OH. This product is intended for research and analytical applications. H-Gly-Pro-OH is an end product of collagen metabolism that is further cleaved by prolidase.
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Cat. No.: HY-175350
CAS No.: 2688118-55-8
Synonyms: OncoFAP glidotin
Target:  

FAP Microtubule/Tubulin

Research Areas:  

Cancer

OncoFAP-GlyPro-MMAE is a FAP small molecule-drug conjugate (SMDC) with an IC50 of 0.49  nM. OncoFAP-GlyPro-MMAE consists of a FAP Ligand OncoFAP (HY-145938), a Tubulin inhibitor (MMAE) (HY-15162) and a linker. OncoFAP-GlyPro-MMAE can be used for cancers like renal cancer research .
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Cat. No.: HY-W018717
CAS No.: 14296-92-5
Research Areas:  

Others

Boc-Gly-Pro-OH is a Glycine (HY-Y0966) derivative .
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Cat. No.: HY-137220
CAS No.: 65022-15-3
Purity:  99.38%
Research Areas:  

Others

Z-Gly-Pro-pNA is a substrate for measuring prolyl endopeptidase (PEP) inhibitory activity .
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