AKT/PI3K/NF-κB

Natural Products Microorganisms Disease Research Fields Inflammation/Immunology

Ser/Thr Protease Cathepsin Autophagy SARS-CoV Atg8/LC3 NO Synthase COX p62 Arginase PTEN NF-κB PI3K Akt p38 MAPK ERK Reactive Oxygen Species (ROS)

Flavonoids Malus pumila Mill. Rosaceae Metabolic Disease Phenols Polyphenols Plants Dihydrochalcones Disease Research Fields

Caspase JAK GLUT STAT Apoptosis Bacterial SGLT mTOR Akt NF-κB PI3K DNA/RNA Synthesis

Flavonoids Leguminosae Isoflavanones Derris trifoliata Lour. Plants Disease Research Fields Biological Pesticide Research Cancer Agricultural Research

Akt Autophagy Apoptosis

Panax ginseng C. A. Meyer Triterpenes Terpenoids Plants Disease Research Fields Inflammation/Immunology Araliaceae

NF-κB PI3K JAK Apoptosis

Infection Alkaloids Piperidine Alkaloids Leguminosae Plants Sophora flavescens Aiton Disease Research Fields Inflammation/Immunology

Autophagy Apoptosis NF-κB PI3K Akt MEK ERK PTEN

Infection Alkaloids Piperidine Alkaloids Leguminosae Sophora japonica L. Plants Disease Research Fields Inflammation/Immunology

Autophagy Apoptosis NF-κB PI3K Akt MEK ERK

Other Monoterpenes other families Terpenoids Other Diseases Plants Disease Research Fields

NF-κB PI3K Akt TGF-beta/Smad

Terpenoids Sesquiterpenes Plants Curcuma phaeocaulis Valeton Disease Research Fields Cancer Zingiberaceae

Apoptosis

Simple Phenylpropanols Cistanche deserticola Ma Metabolic Disease Orobanchaceae Phenols Polyphenols Phenylpropanoids Plants Disease Research Fields

Apoptosis Reactive Oxygen Species (ROS) Akt mTOR PI3K NO Synthase COX p38 MAPK Toll-like Receptor (TLR) Amyloid-β

Flavonols Flavonoids Leguminosae Plants Vigna unguiculata Disease Research Fields Inflammation/Immunology

Toll-like Receptor (TLR) Apoptosis

Animals Disease Research Fields Cancer Steroids

PI3K Akt NF-κB AP-1 GSK-3 CDK

Plants Moraceae Endogenous metabolite Simple Phenylpropanols Other Diseases Phenols Polyphenols Phenylpropanoids Disease Research Fields Morus alba Linn.

Endogenous Metabolite NF-κB Keap1-Nrf2 mTOR HIF/HIF Prolyl-Hydroxylase

Alkaloids Chelidonium majus Metabolic Disease Quinoline Alkaloids Plants Disease Research Fields Papaveraceae

Indoleamine 2,3-Dioxygenase (IDO) NF-κB p38 MAPK PI3K Akt Apoptosis Reactive Oxygen Species (ROS) Mitochondrial Metabolism DNA/RNA Synthesis ROCK LDLR

Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Inflammation/Immunology

Endogenous Metabolite Interleukin Related TNF Receptor AMPK Sirtuin STAT PI3K NF-κB JAK p38 MAPK JNK Akt Apoptosis Ferroptosis

Natural Products Endogenous metabolite Disease Research Fields Inflammation/Immunology

Interleukin Related TNF Receptor Endogenous Metabolite AMPK Sirtuin STAT PI3K NF-κB JAK p38 MAPK JNK Akt Apoptosis Ferroptosis

Alkaloids Rutaceae Quinoline Alkaloids Plants Skimmia reevesiana Fort. Disease Research Fields Inflammation/Immunology

Cholinesterase (ChE) PI3K Akt NF-κB

Alkaloids Piperidine Alkaloids Liliaceae Other Diseases Plants Fritillaria ussuriensis Maxim. Disease Research Fields

PI3K NF-κB Akt NOD-like Receptor (NLR) Pyroptosis Ferroptosis

Stilbenes Gnetum cleistostachyum C. Y. Cheng Gnetaceae Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology

Carnitine Palmitoyltransferase (CPT) Reactive Oxygen Species (ROS) Autophagy Apoptosis NF-κB PI3K Akt MMP Keap1-Nrf2

Infection Alkaloids Phellodendron amurense Rupr. Rutaceae Plants Disease Research Fields Isoquinoline Alkaloids

Others