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Results for "

Gly-Pro

" in MedChemExpress (MCE) Product Catalog:

49

Inhibitors & Agonists

3

Fluorescent Dye

38

Peptides

2

Natural
Products

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D1670
    Z-Gly-Pro-AMC
    3 Publications Verification

    		 Fluorescent Dye Others
    Z-Gly-Pro-AMC is a fluorogenic substrate. Z-Gly-Pro-AMC is hydrolyzed by prolyl endopeptidase to generate highly fluorescent 7-Amino-4-methylcoumarin (HY-D0027). (λex=380 nm, λem=465 nm) .
    Z-Gly-Pro-AMC
  • HY-W016887
    Glycyl-L-proline

    H-Gly-Pro-OH; Gly-Pro

    		 Endogenous Metabolite Apoptosis Metabolic Disease Cancer
    Glycyl-L-proline (H-Gly-Pro-OH) is a dipeptide. Glycyl-L-proline can induce MCF-7 cells apoptosis. Glycyl-L-proline can enhance the inhibitory effect of the PRODH/POX knockout on collagen and DNA biosynthesis. Glycyl-L-proline can inhibit Gly-Sar and L-proline transport. Glycyl-L-proline can be used for the researches of cancer and metabolic disease, such as breast cancer .
    Glycyl-L-proline
  • HY-145983
    Suc-Gly-Pro-AMC
    1 Publications Verification

    		 FAP Prolyl Endopeptidase (PREP) Cancer
    Suc-Gly-Pro-AMC is a fluorescent substrate. Suc-Gly-Pro-AMC is a fibroblast activation protein (FAP) specific substrate. Suc-Gly-Pro-AMC reacts with recombinant porcine prolyl oligopeptidase. Suc-Gly-Pro-AMC can be used to study the activity of FAP, prolyl endopeptidase (PREP). Suc-Gly-Pro-AMC is used in glioma research .
    Suc-Gly-Pro-AMC
  • HY-119244
    Gly-Pro-pNA hydrochloride

    		Dipeptidyl Peptidase Metabolic Disease
    Gly-Pro-pNA hydrochloride is a chromogenic peptide substrate that can be cleaved by the circulating enzyme dipeptidyl peptidase IV (DPP IV). Gly-Pro-pNA hydrochloride is mainly used to detect the activity of aminopeptidases such as DPP IV. Gly-Pro-pNA hydrochloride can be investigated as an experimental antidiabetic agent .
    Gly-Pro-pNA hydrochloride
  • HY-P2661
    FA-Leu-Gly-Pro-Ala-OH

    		Biochemical Assay Reagents Bacterial Infection
    FA-Leu-Gly-Pro-Ala-OH is a furylacryloyl-terminal tetrapeptide that serves as a substrate for bacterial collagenase and spirochete metalloendopeptidase. FA-Leu-Gly-Pro-Ala-OH is specifically hydrolyzed by spirochete collagenase only at the Leu-Gly bond. FA-Leu-Gly-Pro-Ala-OH can be used to determine the equilibrium constant of peptide bond hydrolysis, and also to detect collagenase-mediated cleavage reactions via turbidimetry based on absorbance reduction .
    FA-Leu-Gly-Pro-Ala-OH
  • HY-137834
    Gly-Pro-AMC hydrobromide
    1 Publications Verification

    		 Fluorescent Dye Others
    Gly-Pro-AMC hydrobromide is a fluorescent dye, it can be used as a specific fluorescent substrate for detecting Dipeptidyl peptidase IV (DPP-IV) activity .
    Gly-Pro-AMC hydrobromide
  • HY-P0074
    GPRP
    3 Publications Verification

    Gly-Pro-Arg-Pro; Pefa 6003

    		 Thrombin Cardiovascular Disease
    GPRP (Gly-Pro-Arg-Pro; Pefa 6003) is a fibrin polymerization inhibitor that inhibits the interaction between fibrinogen and the platelet membrane glycoprotein Ⅱb/IIIa complex (glycoprotein IIb/IIIa receptor) . GPRP increases the level of free thrombin in activated platelet-rich plasma by reducing the adsorption of thrombin onto fibrin. GPRP inhibits platelet aggregation and prolongs the thrombin-initiated clotting time in plasma. GPRP is applicable for research related to thrombosis and thrombotic diseases .
    GPRP
  • HY-P4486
    H-Pro-Gly-Pro-OH

    Pro-Gly-Pro

    		 Drug Derivative Others
    H-Pro-Gly-Pro-OH is a collagen-derived matrikine that has classically been described as a neutrophil chemoattractant. H-Pro-Gly-Pro-OH is perfectly positioned to focus neutrophils on the site required and direct a localized repair response. H-Pro-Gly-Pro-OH activates the transcription of neurotrophins and their receptor genes after cerebral ischemia .
    H-Pro-Gly-Pro-OH
  • HY-P0074A
    GPRP acetate
    3 Publications Verification

    Gly-Pro-Arg-Pro acetate; Pefa 6003 acetate

    		 Integrin Cardiovascular Disease
    GPRP acetate (Gly-Pro-Arg-Pro acetate) is a fibrin polymerization inhibitor that inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa) .
    GPRP acetate
  • HY-117483
    Gly-Pro-Glu

    		iGluR Neurological Disease
    Gly-Pro-Glu is a neuroactive peptide with a potent action on acetylcholine release. Gly-Pro-Glu is the N-terminal tripeptide of insulin-like growth factor-I. Gly-Pro-Glu inhibits glutamate binds to N-methyl-D-aspartate (NMDA) receptor with an IC50 value of 14.7 μM. Gly-Pro-Glu can be used for the research of neuroprotection .
    Gly-Pro-Glu
  • HY-P4344
    Met-Gly-Pro-AMC

    		MetAP Others
    Met-Gly-Pro-AMC is a fluorescent peptide substrate of MetAP2 .
    Met-Gly-Pro-AMC
  • HY-W016887R
    Glycyl-L-proline (Standard)

    H-Gly-Pro-OH (Standard); Gly-Pro (Standard)

    		 Reference Standards Endogenous Metabolite Metabolic Disease
    H-Gly-Pro-OH (Standard) is the analytical standard of H-Gly-Pro-OH. This product is intended for research and analytical applications. H-Gly-Pro-OH is an end product of collagen metabolism that is further cleaved by prolidase.
    Glycyl-L-proline (Standard)
  • HY-175350
    OncoFAP-GlyPro-MMAE

    OncoFAP glidotin

    		 FAP Microtubule/Tubulin Cancer
    OncoFAP-GlyPro-MMAE is a FAP small molecule-drug conjugate (SMDC) with an IC50 of 0.49  nM. OncoFAP-GlyPro-MMAE consists of a FAP Ligand OncoFAP (HY-145938), a Tubulin inhibitor (MMAE) (HY-15162) and a linker. OncoFAP-GlyPro-MMAE can be used for cancers like renal cancer research .
    OncoFAP-GlyPro-MMAE
  • HY-P4217
    Z-Gly-Pro-Arg-AMC hydrochloride
    1 Publications Verification

    		 Cathepsin Others
    Z-Gly-Pro-Arg-AMC hydrochloride a fluorescent trypsin and cathepsin K substrate. Z-Gly-Pro-Arg-AMC hydrochloride can be used to determine trypsin and cathepsin K activity .
    Z-Gly-Pro-Arg-AMC hydrochloride
  • HY-P4846
    Ac-Pro-Gly-Pro-OH
    2 Publications Verification

    		 CXCR Apoptosis IFNAR TNF Receptor Interleukin Related Infection Inflammation/Immunology
    Ac-Pro-Gly-Pro-OH is an endogenous degradation product of extracellular collagen and acts as a CXCR2 agonist . Ac-Pro-Gly-Pro-OH exerts bactericidal activity by generating hydrogen peroxide, inhibits pulmonary inflammation, and reduces immune cell apoptosis (apoptosis). Ac-Pro-Gly-Pro-OH promotes the production of IFN-γ and inhibits the production of TNF-α and IL-6 in leukocytes. Ac-Pro-Gly-Pro-OH increases the survival rate of mice in sepsis models, enhances the bactericidal activity of neutrophils, acts as a neutrophil chemoattractant, induces neutrophil polarization, and regulates inflammatory and repair processes. Ac-Pro-Gly-Pro-OH induces chronic inflammation and tissue remodeling through sustained action. Ac-Pro-Gly-Pro-OH is released via alkaline hydrolysis of corneal proteins in alkali-injured eyes, thereby driving the early infiltration of neutrophils into the cornea. Ac-Pro-Gly-Pro-OH is applicable to research related to sepsis, chronic obstructive pulmonary disease, cystic fibrosis, bronchiolitis obliterans syndrome, severe asthma, idiopathic pulmonary fibrosis, and corneal ulcer .
    Ac-Pro-Gly-Pro-OH
  • HY-W018717
    Boc-Gly-Pro-OH

    		Amino Acid Derivatives Others
    Boc-Gly-Pro-OH is a Glycine (HY-Y0966) derivative .
    Boc-Gly-Pro-OH
  • HY-137220
    Z-Gly-Pro-pNA

    		Prolyl Endopeptidase (PREP) Others
    Z-Gly-Pro-pNA is a substrate for measuring prolyl endopeptidase (PEP) inhibitory activity .
    Z-Gly-Pro-pNA
  • HY-P4294
    H-Gly-Pro-Gly-OH

    Gly-Pro-Gly

    		 Amino Acid Derivatives Others
    H-Gly-Pro-Gly-OH is a tripeptide containing glycine and proline. H-Gly-Pro-Gly-OH can be used for the synthesis of other polypeptides, such as (Pro Gly Gly)n .
    H-Gly-Pro-Gly-OH
  • HY-E70528
    HRV-3C protease fuses with GST

    		Biochemical Assay Reagents Others
    HRV-3C protease fuses with GST is a recombinant protease that combines human rhinovirus (HRV) type 14 3C protease and a GST-tag. HRV-3C protease fuses with GST can specifically recognize the short peptide Leu-Glu-Val-Leu-Phe-Gln-Gly-Pro at 4°C and cleave between Gln and Gly amino acids .
    HRV-3C protease fuses with GST
  • HY-W095029
    Cbz-Gly-Pro-OH

    		Biochemical Assay Reagents Others
    Cbz-Gly-Pro-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Cbz-Gly-Pro-OH
  • HY-P3792
    Mca-Pro-Leu-Gly-Pro-D-Lys(Dnp)

    		Biochemical Assay Reagents Others
    Mca-Pro-Leu-Gly-Pro-D-Lys(Dnp) is a FRET substrate of Thimet oligopeptidase. Mca-Pro-Leu-Gly-Pro-D-Lys(Dnp) can be used for the determination of Thimet oligopeptidase activity .
    Mca-Pro-Leu-Gly-Pro-D-Lys(Dnp)
  • HY-134113
    Z-Gly-Pro-Arg-pNA

    CBZ-Chromozym TH

    		 Biochemical Assay Reagents Others
    Z-Gly-Pro-Arg-pNA (z-GPR-pNA) is a photometric substrate in Prostate-Specific Antigen (PSA) activation protease assays. Z-Gly-Pro-Arg-pNA (z-GPR-pNA) can be used for the test of trypsin activity .
    Z-Gly-Pro-Arg-pNA
  • HY-175353
    TriOncoFAP-GlyPro-MMAE

    		FAP Cancer
    TriOncoFAP-GlyPro-MMAE is a small molecule drug conjugate (SMDC) targeting fibroblast activation protein (FAP) with an IC50 of 13 pmol/L. TriOncoFAP-GlyPro-MMAE combines a FAP-targeting ligand (TriOnco), a cleavable glycine-proline linker, and a cytotoxic payload (MMAE) .
    TriOncoFAP-GlyPro-MMAE
  • HY-151871
    ICeD-2

    		Dipeptidyl Peptidase HIV Infection
    ICeD-2 is a inducer of cell death, can induce HIV-1 infected cell kill. ICeD-2-mediated HIV-1 infected cell kill is dependent on HIV-1 protease activity. ICeD-2 potently blocks hydrolysis of Gly-Pro-AMC by dipeptidyl peptidase DPP8 and DPP9. ICeD-2 shows strong stabilization of DPP9 in PBMCs .
    ICeD-2
  • HY-137834A
    Gly-Pro-AMC

    		Biochemical Assay Reagents Others
    Gly-Pro-AMC is a biological active peptide. (This is a fluorescent dipeptidylaminopeptidase IV substrate, Abs/Em=353/442 nm.)
    Gly-Pro-AMC
  • HY-P4496
    Tos-Gly-Pro-Lys-pNA

    		Phosphatase Others
    Tos-Gly-Pro-Lys-pNA is a substrate for the serine protease ALP and can be used to measure the activity of this enzyme .
    Tos-Gly-Pro-Lys-pNA
  • HY-P0020A
    Tos-Gly-Pro-Arg-ANBA-IPA acetate

    tos-GPR-ANBA-IPA acetate

    		 Biochemical Assay Reagents Others
    Tos-Gly-Pro-Arg-ANBA-IPA (tos-GPR-ANBA-IPA) acetate is a chromogenic peptide substrate. Tos-Gly-Pro-Arg-ANBA-IPA acetate can be used for luminescence measurement .
    Tos-Gly-Pro-Arg-ANBA-IPA acetate
  • HY-170865
    OncoFAP-GlyPro-MMAF

    		Drug-Linker Conjugates for ADC Cancer
    OncoFAP-GlyPro-MMAF is a Drug-Linker Conjugate for ADC with potent antitumor activity. OncoFAP-GlyPro-MMAF consists of Monomethylauristatin F (HY-15579) and a linker. OncoFAP-GlyPro-MMAF can be used for synthesis of ADCs .
    OncoFAP-GlyPro-MMAF
  • HY-P11431
    Cyclo(Gly-Pro)

    		IGF-1R Neurological Disease Inflammation/Immunology
    Cyclo(Gly-Pro) is a cyclic dipeptide. Cyclo(Gly-Pro) can be derived from the Nterminus of the IGF-1. Cyclo(Gly-Pro) attenuates nociceptive behaviour and inflammatory response in mice .
    Cyclo(Gly-Pro)
  • HY-P0020
    Tos-Gly-Pro-Arg-ANBA-IPA

    tos-GPR-ANBA-IPA

    		 Biochemical Assay Reagents Others
    Tos-Gly-Pro-Arg-ANBA-IPA is a chromogenic peptide substrate. Tos-Gly-Pro-Arg-ANBA-IPA can be used for luminescence measurement .
    Tos-Gly-Pro-Arg-ANBA-IPA
  • HY-168772
    Glycyl-L-Proline TFA

    H-Gly-Pro-OH TFA

    		 Amino Acid Derivatives Others
    Glycyl-L-Proline TFA (H-Gly-Pro-OH TFA) is a dipeptide, which is composed of a glycine and a L-proline. Glycyl-L-Proline TFA can be used in research about the co-relationship between transmembrane potential/proton gradient and intestinal transport .
    Glycyl-L-Proline TFA
  • HY-178853
    3,4-Dihydroxybenzeneethanimidamide

    		Others Inflammation/Immunology
    3,4-Dihydroxybenzeneethanimidamide can selectively react with Gly-Pro, the substrate for prolidase, and the prolidase activity is measured by monitoring the decrease in FL intensities. 3,4-Dihydroxybenzeneethanimidamide can be used for the study of inflammation .
    3,4-Dihydroxybenzeneethanimidamide
  • HY-P2718
    Z-Gly-Pro-Gly-Gly-Pro-Ala-OH

    		Biochemical Assay Reagents Others
    Z-Gly-Pro-Gly-Gly-Pro-Ala-OH is a collagenase substrate that induces planulae to settle .
    Z-Gly-Pro-Gly-Gly-Pro-Ala-OH
  • HY-A0299A
    H-Gly-Pro-Hyp-OH acetate

    		Dipeptidyl Peptidase Metabolic Disease
    H-Gly-Pro-Hyp-OH acetate is a dipeptidyl peptidase 4 (DPP-4) inhibitor with an IC50 value of 2.51 mM. H-Gly-Pro-Hyp-OH acetate is promising for research of diabetes .
    H-Gly-Pro-Hyp-OH acetate
  • HY-P2708
    H-Gly-Pro-Arg-Pro-NH2

    		Integrin Cardiovascular Disease
    H-Gly-Pro-Arg-Pro-NH2 is a peptide that mimics the N-terminal Gly-Pro-Arg region in the a chain of fibrin protein. H-Gly-Pro-Arg-Pro-NH2 prevents fibrin polymerization .
    H-Gly-Pro-Arg-Pro-NH2
  • HY-P4292
    H-Gly-Pro-Gly-NH2

    		HIV Amino Acid Derivatives Infection
    H-Gly-Pro-Gly-NH2 is a tripeptide that inhibits HIV-1 replication. H-Gly-Pro-Gly-NH2 inhibits the activity of HIV-1 IIIB and HIV-2 ROD with EC50 values of 35 µM and 30 µM, respectively. H-Gly Pro Gly NH2 inhibits HIV-1 replication in vitro by interfering with capsid formation. H-Gly Pro Gly NH2 has antiviral activity and can be used for virus research .
    H-Gly-Pro-Gly-NH2
  • HY-P4366
    Tos-Gly-Pro-Lys-AMC

    		Ser/Thr Protease Others
    Tos-Gly-Pro-Lys-AMC is a fluorogenic peptide substrate of tryptase .
    Tos-Gly-Pro-Lys-AMC
  • HY-P4448
    Ac-Gly-Pro-AFC

    		Fluorescent Dye Others
    Ac-Gly-Pro-AFC is a fluorogenic substrate for the determination of fibroblast activation protein (FAP) endopeptidase activity .
    Ac-Gly-Pro-AFC
  • HY-163382
    Cbz-Gly-Pro-Ala-O-cinnamyl

    		Beta-lactamase Cholinesterase (ChE) Amyloid-β Neurological Disease
    Cbz-Gly-Pro-Ala-O-cinnamyl (compound 25) is a small peptide targeting BACE-1 and AChE with the IC50 values of 0.02 μM and 1 μM, respectively. Cbz-Gly-Pro-Ala-O-cinnamyl shows neuroprotective effect and can be used for study of Alzheimer’s disease .
    Cbz-Gly-Pro-Ala-O-cinnamyl
  • HY-P4593
    Z-Gly-Pro-Arg-4MβNA

    		Thrombin Others
    Z-Gly-Pro-Arg-4MβNA is the cleavage of the substrate of thrombin to release free 4-methoxy-2-naphthylamine (4MβNA). Free 4MβNA can be captured by 5-nitrosalicylaldehyde to produce an insoluble yellow fluorescent and marks the site of thrombin activity .
    Z-Gly-Pro-Arg-4MβNA
  • HY-P10007
    Z-Gly-Pro-Phe-Leu-CHO

    Z-GPFL-CHO

    		 Proteasome Cancer
    Z-Gly-Pro-Phe-Leu-CHO (Z-GPFL-CHO) is a tetrapeptide aldehyde that acts as a highly selective and potent proteasomal inhibitor (Ki = 1.5 µM for branched chain amino acid preferring, 2.3 µM for small neutral amino acid preferring, and 40.5 µM for chymotrypsin-like activities; IC50 = 3.1 µM for peptidyl-glutamyl peptide hydrolyzing activity) .
    Z-Gly-Pro-Phe-Leu-CHO
  • HY-156960
    JNJ-40929837

    		Aminopeptidase Leukotriene Receptor Inflammation/Immunology
    JNJ-40929837 is a selective and orally active LTA4H (leukotriene A4 hydrolase) inhibitor. JNJ-40929837 effectively inhibits aminopeptidase activity and causes serum accumulation of Pro-Gly-Pro. JNJ-40929837 can be used in asthma research .
    JNJ-40929837
  • HY-156960A
    JNJ-40929837 succinate

    		Aminopeptidase Leukotriene Receptor Inflammation/Immunology
    JNJ-40929837 succinate is a selective and orally active LTA4H (leukotriene A4 hydrolase) inhibitor. JNJ-40929837 succinate effectively inhibits aminopeptidase activity and causes serum accumulation of Pro-Gly-Pro. JNJ-40929837 succinate can be used in asthma research .
    JNJ-40929837 succinate
  • HY-P11367
    Boc-Ala-Gly-Pro-Arg-AMC

    		Fluorescent Dye Ser/Thr Protease Infection Metabolic Disease
    Boc-Ala-Gly-Pro-Arg-AMC is a synthetic fluorescent substrate, widely used for the detection of protease activity. Boc-Ala-Gly-Pro-Arg-AMC can be used to detect the activity of serine proteases and the oligopeptide enzyme B of Trypanosoma brucei .
    Boc-Ala-Gly-Pro-Arg-AMC
  • HY-P2661A
    FA-Leu-Gly-Pro-Ala-OH TFA

    		Biochemical Assay Reagents Bacterial Infection
    FA-Leu-Gly-Pro-Ala-OH TFA is a furylacryloyl-terminal tetrapeptide that serves as a substrate for bacterial collagenase and spirochete metalloendopeptidase. FA-Leu-Gly-Pro-Ala-OH TFA is specifically hydrolyzed by spirochete collagenase only at the Leu-Gly bond. FA-Leu-Gly-Pro-Ala-OH TFA can be used to determine the equilibrium constant of peptide bond hydrolysis, and also to detect collagenase-mediated cleavage reactions via turbidimetry based on absorbance reduction .
    FA-Leu-Gly-Pro-Ala-OH TFA
  • HY-W800711
    SPDP-Gly-Pro-NHS ester

    		Biochemical Assay Reagents Others
    SPDP-Gly-Pro-NHS ester is a linker with SPDP and NHS ester moieties. The SPDP is an amine and thiol reactive crosslinker. It is also membrane permeable, allowing it to participate in intracellular crosslinking reactions. The NHS ester is amine reactive and forms stable amide bonds.
    SPDP-Gly-Pro-NHS ester
  • HY-W800713
    SPDP-Gly-Pro-acid

    		Biochemical Assay Reagents Others
    SPDP-Gly-Pro-acid is a linker with SPDP and carboxylic acid moieties. The SPDP is an amine and thiol reactive crosslinker. It is also membrane permeable, allowing it to participate in intracellular crosslinking reactions. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
    SPDP-Gly-Pro-acid
  • HY-P11627
    Cyclo(Pro-Hyp)

    		Endogenous Metabolite Others
    Cyclo(Pro-Hyp) is a collagen-derived cyclic dipeptide, and its related collagen breakdown product Gly-Pro-Hyp promotes the growth of skin fibroblasts and participates in tissue reconstruction, exhibiting biological activity.
    Cyclo(Pro-Hyp)
  • HY-151871A
    cis-ICeD-2

    		HIV Dipeptidyl Peptidase Drug Isomer Infection
    cis-ICeD-2 is the cis isomer of ICeD-2 (HY-151871). ICeD-2 is a cell death inducer that induces cell death in HIV-1-infected cells. ICeD-2-mediated killing of HIV-1-infected cells is dependent on HIV-1 protease activity. ICeD-2 effectively blocks the hydrolysis of Gly-Pro-AMC by the dipeptidyl peptidases DPP8 and DPP9. ICeD-2 demonstrates strong stability against DPP9 in PBMCs. .
    cis-ICeD-2

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