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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
72 Results for "
UVB
" in MedChemExpress (MCE) Product Catalog:
Products (72)
72 Results for "UVB" in MCE Product Catalog:
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Prinaberel (ERB-041) is a potent and selective estrogen receptor (ER) β agonist with IC50s of 5.4, 3.1 and 3.7 nM for human, rat and mouse ERβ, respectively. Prinaberel displays >200-fold selectivity for ERβ over ERα. Prinaberel is a potent skin cancer chemopreventive agent that acts by dampening the WNT/β-catenin signaling pathway. Prinaberel induces ovarian cancer apoptosis .
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2 Cited Publications
Cat. No.: HY-N6641
CAS No.: 21516-68-7
Category:
Natural Products other families Microorganisms Pigments Plants Disease Research Fields Inflammation/Immunology Food Research
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2 Cited Publications
Synonyms: 3,4-Dihydroxy-benzenepropanoic acid
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2 Cited Publications
Cat. No.: HY-N0244
CAS No.: 28543-07-9
Category:
Flavonoids Flavanols Phenols Polyphenols Plants Camellia sinensis (L.) O. Ktze. Disease Research Fields Cancer Theaceae
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Environmental Pollutants PPAR Estrogen Receptor/ERR Biochemical Assay Reagents Cytochrome P450
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Octocrylene is an organic ultraviolet (UV) filter that absorbs mainly UVB radiation and shorter UVA wavelengths. Octocrylene acts as a partial agonist of PPARγ, which alters the gene transcription profile of lipid metabolism enzymes. In addition, Octocrylene is cytotoxic and genotoxic to human skin fibroblasts and mediates the biosynthesis of estrogens such as estriol in zebrafish larvae, while affecting antioxidant pathways including glutathione transferase and peroxisomes .
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1
1 Cited Publications
Cat. No.: HY-B0897
CAS No.: 103597-45-1
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Bisoctrizole is a broad-spectrum UVA/UVB absorber that belongs to the benzotriazole class of compounds. Bisoctrizole absorbs UV light through hydroxyphenyl groups, causing reversible electronic transitions, thereby converting light energy into heat energy, inhibiting UV-induced material or skin damage. Bisoctrizole is highly efficient in capturing UVA (320-400 nm) and some UVB (280-320 nm) radiation. Bisoctrizole delays the photodegradation of materials such as silicones, improving their UV aging resistance or enhancing the photoprotective ability of sunscreen products .
1
1 Cited Publications
Cat. No.: HY-W010169
CAS No.: 555-06-6
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Cat. No.: HY-W251181
CAS No.: 1428450-95-6
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Isobutylamido thiazolyl resorcinol is a selective hTyr inhibitor with an IC50 of 1.1 μM. Isobutylamido thiazolyl resorcinol shows an IC50 of 108 μM against mushroom Tyrosinase. Isobutylamido thiazolyl resorcinol effectively prevents pigmentation caused by UVB irradiation. Isobutylamido thiazolyl resorcinol significantly improves the visibility of acne-induced hyperpigmentation .
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Cardiovascular Disease other families Ketones, Aldehydes, Acids Plants Disease Research Fields
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Cat. No.: HY-P0064
CAS No.: 221227-05-0
Synonyms: Palmitoyl Tetrapeptide-7
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Cat. No.: HY-N5048
CAS No.: 122965-41-7
Synonyms: 6'-O-Galloyl paeoniflorin
Synonyms: Octyl triazone
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Ethylhexyl triazone is an approved ultraviolet-B (UV-B) chemical filter for commercial sunscreens.
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Dioxybenzone (Benzophenone-8; UV-24) is an organic compound used to block UVB and short-wave UVA (ultraviolet) radiation. Dioxybenzone has orally activity. Dioxybenzone exhibits estrogenic disrupting effect. Dioxybenzone up-regulates inflammatory cytokines. Dioxybenzone can be used for cancer, reproductive system disease and inflammatory disease study .
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Natural Products Plants Moraceae Endogenous metabolite Human Gut Microbiota Metabolites Ficus carica L. Other Diseases Phenols Polyphenols Disease Research Fields
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Cat. No.: HY-N0754
CAS No.: 877822-40-7
Synonyms: tetra-isopalmitoyl Ascorbic acid; IPAA; Tetrahexyldecyl Ascorbate
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Ascorbyl tetra-2-hexyldecanoate (tetra-isopalmitoyl Ascorbic acid; IPAA) is a lipophilic derivative of vitamin C (L-ascorbic acid). Ascorbyl tetra-2-hexyldecanoate (100 μM ) can prevent the decrease in viability of HaCaT keratinocytes induced by UVB, hydrogen peroxide, or tert-butyl hydroperoxide, and reduce the production of IL-1α and prostaglandin E2 (PGE2). Topical application of ascorbyl tetra-2-hexyldecanoate (1%) increases epidermal viability thickness, stratum corneum water content, and skin smoothness, and reduces skin roughness in hairless mice. Ascorbyl tetra-2-hexyldecanoate can be used to develop skin whitening agents in the beauty industry.
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Ensulizole is a sulfonated UV absorber and can intense UVB and partial UVA absorption. Ensulizole can damage the DNA through the generation of reactive oxygen species (ROS) upon UV or sunlight irradiation .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
