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Results for "

UVB

" in MedChemExpress (MCE) Product Catalog:

70

Inhibitors & Agonists

1

Biochemical Assay Reagents

3

Peptides

23

Natural
Products

12

Isotope-Labeled Compounds

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W020044
    DL-alpha-Tocopherol
    Maximum Cited Publications
    7 Publications Verification

    DL-α-Tocopherol

    		 Environmental Pollutants Ferroptosis Apoptosis DNA/RNA Synthesis Cancer
    DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB .
    DL-alpha-Tocopherol
  • HY-B1008
    4-Aminobenzoic acid
    1 Publications Verification

    PABA; p-Aminobenzoic acid

    		 Environmental Pollutants Endogenous Metabolite Bacterial Infection
    4-Aminobenzoic acid is an intermediate in the synthesis of folic acid by bacteria, plants and fungi. 4-Aminobenzoic acid has antibacterial and plant growth regulating properties .
    4-Aminobenzoic acid
  • HY-N6641
    Monascin
    2 Publications Verification

    		 Keap1-Nrf2 PPAR Inflammation/Immunology Cancer
    Monascin is a kind of azaphilonoid pigments extracted from Monascus pilosus-fermented rice (red-mold rice). Monascin also exhibits anti-tumor-initiating activity and anti-inflammatory activity with oral administration. Monascin inhibits the activation of NOR 1 (an NO donor). Monascin is a Nrf2 activator and PPARγ agonist .
    Monascin
  • HY-N2406
    Dihydrocaffeic acid
    2 Publications Verification

    3,4-Dihydroxy-benzenepropanoic acid

    		 p38 MAPK Endogenous Metabolite Reactive Oxygen Species (ROS) NO Synthase Inflammation/Immunology
    Dihydrocaffeic acid is a microbial metabolite of flavonoids. Dihydrocaffeic acid scavenges intracellular ROS and increases nitric oxide synthase activity. Dihydrocaffeic acid reduces phosphorylation of MAPK p38 and prevent UVB-induced skin damage. Dihydrocaffeic acid has antioxidant, anti-inflammatory and anti-cartilage degradation activities .
    Dihydrocaffeic acid
  • HY-W251181
    Isobutylamido thiazolyl resorcinol

    		Tyrosinase Metabolic Disease
    Isobutylamido thiazolyl resorcinol is a selective hTyr inhibitor with an IC50 of 1.1  μM. Isobutylamido thiazolyl resorcinol shows an IC50 of 108  μM against mushroom Tyrosinase. Isobutylamido thiazolyl resorcinol effectively prevents pigmentation caused by UVB irradiation. Isobutylamido thiazolyl resorcinol significantly improves the visibility of acne-induced hyperpigmentation .
    Isobutylamido thiazolyl resorcinol
  • HY-N0244
    Theaflavin-3'-gallate
    2 Publications Verification

    		 Xanthine Oxidase Apoptosis Necroptosis Cancer
    Theaflavin-3'-gallate is a monomer of theaflavins found in black tea, which has anti-UVB damage activity and inhibits cell apoptosis and necroptosis. Theaflavin-3'-gallate acts as a pro-oxidant and induces oxidative stress in cancer cells, inhibiting xanthine oxidase (OX), with an IC50 of 7.6 μM .
    Theaflavin-3'-gallate
  • HY-14933
    Prinaberel
    3 Publications Verification

    ERB-041

    		 Estrogen Receptor/ERR Wnt Apoptosis Cancer
    Prinaberel (ERB-041) is a potent and selective estrogen receptor (ER) β agonist with IC50s of 5.4, 3.1 and 3.7 nM for human, rat and mouse ERβ, respectively. Prinaberel displays >200-fold selectivity for ERβ over ERα. Prinaberel is a potent skin cancer chemopreventive agent that acts by dampening the WNT/β-catenin signaling pathway. Prinaberel induces ovarian cancer apoptosis .
    Prinaberel
  • HY-N2007
    Veratric acid

    3,4-Dimethoxybenzoic acid

    		 COX Reactive Oxygen Species (ROS) Cardiovascular Disease Inflammation/Immunology
    Veratric acid (3,4-Dimethoxybenzoic acid) is an orally active phenolic compound derived from vegetables and fruits, has antioxidant and anti-inflammatory activities . Veratric acid also acts as a protective agent against hypertension-associated cardiovascular remodelling . Veratric acid reduces upregulated COX-2 expression, and levels of PGE2, IL-6 after UVB irradiation .
    Veratric acid
  • HY-A0087
    Octocrylene
    2 Publications Verification

    		 Environmental Pollutants PPAR Estrogen Receptor/ERR Biochemical Assay Reagents Cytochrome P450 Others
    Octocrylene is an organic ultraviolet (UV) filter that absorbs mainly UVB radiation and shorter UVA wavelengths. Octocrylene acts as a partial agonist of PPARγ, which alters the gene transcription profile of lipid metabolism enzymes. In addition, Octocrylene is cytotoxic and genotoxic to human skin fibroblasts and mediates the biosynthesis of estrogens such as estriol in zebrafish larvae, while affecting antioxidant pathways including glutathione transferase and peroxisomes .
    Octocrylene
  • HY-P0064
    Palmitoyl Tetrapeptide-3

    Palmitoyl Tetrapeptide-7

    		 Interleukin Related Inflammation/Immunology
    Palmitoyl Tetrapeptide-3 (Palmitoyl Tetrapeptide-7) is a synthetic peptide corresponding to amino acids 341-344 of the human immunoglobulin heavy chain, with the ability to stimulate phagocytosis. Palmitoyl tetrapeptide-3 reduces interleukin-6 (IL-6) secretion in keratinocytes and inhibits the UVB radiation-exposure inflammatory response of skin. Palmitoyl tetrapeptide-3 It also has anti-inflammatory and anti-aging effects, reducing skin wrinkles by promoting the production of elastic fibers in the papillary dermis .
    Palmitoyl Tetrapeptide-3
  • HY-N5048
    Galloylpaeoniflorin

    6'-O-Galloyl paeoniflorin

    		 NF-κB ERK JNK Nuclear Factor of activated T Cells (NFAT) Keap1-Nrf2 PI3K Akt Reactive Oxygen Species (ROS) Apoptosis DNA/RNA Synthesis Infection Neurological Disease Metabolic Disease Inflammation/Immunology
    Galloylpaeoniflorin (6'-O-Galloyl paeoniflorin) is an orally active galloylated derivative of Paeoniflorin (HY-N0293) found in peony roots with various anti-inflammatory and antioxidant activities. Galloylpaeoniflorin suppresses RANKL-induced activation of ERK, JNK, c-Fos, c-Jun, and NFATc1, and reduces osteoclast-specific gene expression. Galloylpaeoniflorin activates Nrf2 and PI3K/Akt pathways, inhibits NF-κB activation, and scavenges ROS to reduce oxidative DNA, lipid, and protein damage. Galloylpaeoniflorin attenuates neuroinflammation, inhibits apoptosis, reduces Helicobacter pylori-induced gastric mucosa injury and UVB-induced cell damage. Galloylpaeoniflorin can be used for the research of osteoporosis, gastritis, ischemic stroke and skin diseases .
    Galloylpaeoniflorin
  • HY-109655
    Ethylhexyl triazone

    Octyl triazone

    		 Biochemical Assay Reagents Others
    Ethylhexyl triazone is an approved ultraviolet-B (UV-B) chemical filter for commercial sunscreens.
    Ethylhexyl triazone
  • HY-B0966
    Dioxybenzone

    Benzophenone-8; UV-24

    		 Biochemical Assay Reagents Inflammation/Immunology Cancer
    Dioxybenzone (Benzophenone-8; UV-24) is an organic compound used to block UVB and short-wave UVA (ultraviolet) radiation. Dioxybenzone has orally activity. Dioxybenzone exhibits estrogenic disrupting effect. Dioxybenzone up-regulates inflammatory cytokines. Dioxybenzone can be used for cancer, reproductive system disease and inflammatory disease study .
    Dioxybenzone
  • HY-N1750
    3-(2,4-Dihydroxyphenyl)propanoic acid

    		Tyrosinase Metabolic Disease
    3-(2,4-Dihydroxyphenyl) propanoic acid (DPPacid) is a competitive Tyrosinase inhibitor. It exhibits an IC50 value of 3.02 μM against mushroom tyrosinase with L-tyrosine as the substrate, an IC50 value of 62 μM with DL-DOPA as the substrate, and a Ki value of 11.5 μM. 3-(2,4-Dihydroxyphenyl) propanoic acid shows no DPPH radical scavenging activity. It can be used in studies related to ultraviolet B (UVB)-induced hyperpigmentation .
    3-(2,4-Dihydroxyphenyl)propanoic acid
  • HY-N0754
    Eupalinolide A

    		YAP HSP Reactive Oxygen Species (ROS) ERK Autophagy Apoptosis Tyrosinase DNA/RNA Synthesis Neurological Disease Inflammation/Immunology Cancer
    Eupalinolide A is a Yes-associated protein (YAP) degrader and HSP70 inducer. Eupalinolide A inhibits osteogenic differentiation of tendon-derived stem cells (TDSCs). Eupalinolide A induces autophagy in hepatocellular carcinoma cells via activating the ROS/ERK signaling pathway. Eupalinolide A protects PAM212 cells from UVB-, Menadione (HY-B0332)-, or heat shock-induced apoptosis. Eupalinolide A alleviates trauma-induced heterotopic ossification (HO) of Achilles tendon and inhibits growth of MHCC97-L and HCCLM3 hepatocellular carcinoma xenograft tumors in mice. Eupalinolide A can be used for the study of traumatic heterotopic ossification of tendons and hepatocellular carcinoma .
    Eupalinolide A
  • HY-133079
    Ascorbyl tetra-2-hexyldecanoate

    tetra-isopalmitoyl Ascorbic acid; IPAA; Tetrahexyldecyl Ascorbate

    		 Prostaglandin Receptor Endocrinology
    Ascorbyl tetra-2-hexyldecanoate (tetra-isopalmitoyl Ascorbic acid; IPAA) is a lipophilic derivative of vitamin C (L-ascorbic acid). Ascorbyl tetra-2-hexyldecanoate (100 μM ) can prevent the decrease in viability of HaCaT keratinocytes induced by UVB, hydrogen peroxide, or tert-butyl hydroperoxide, and reduce the production of IL-1α and prostaglandin E2 (PGE2). Topical application of ascorbyl tetra-2-hexyldecanoate (1%) increases epidermal viability thickness, stratum corneum water content, and skin smoothness, and reduces skin roughness in hairless mice. Ascorbyl tetra-2-hexyldecanoate can be used to develop skin whitening agents in the beauty industry.
    Ascorbyl tetra-2-hexyldecanoate
  • HY-109654
    Ensulizole

    		Reactive Oxygen Species (ROS) Metabolic Disease
    Ensulizole is a sulfonated UV absorber and can intense UVB and partial UVA absorption. Ensulizole can damage the DNA through the generation of reactive oxygen species (ROS) upon UV or sunlight irradiation .
    Ensulizole
  • HY-B0897
    Bisoctrizole
    1 Publications Verification

    		 Biochemical Assay Reagents Others
    Bisoctrizole is a broad-spectrum UVA/UVB absorber that belongs to the benzotriazole class of compounds. Bisoctrizole absorbs UV light through hydroxyphenyl groups, causing reversible electronic transitions, thereby converting light energy into heat energy, inhibiting UV-induced material or skin damage. Bisoctrizole is highly efficient in capturing UVA (320-400 nm) and some UVB (280-320 nm) radiation. Bisoctrizole delays the photodegradation of materials such as silicones, improving their UV aging resistance or enhancing the photoprotective ability of sunscreen products .
    Bisoctrizole
  • HY-W011168
    8-Bromo-2'-deoxyguanosine

    		Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Inflammation/Immunology Cancer
    8-Bromo-2'-deoxyguanosine is an inflammation-related DNA halogenated adduct and an early biomarker of inflammation-induced oxidative tissue damage. The formation of 8-Bromo-2'-deoxyguanosine precedes that of oxidative and nitrative products, and it can be generated via the MPO-H2O2-Cl --Br - system. 8-Bromo-2'-deoxyguanosine serves as the immunogen for preparing the monoclonal antibody mAb8B3, which can be used to detect early DNA modifications in preclinical models; its urinary level also increases significantly in inflammatory disease models. 8-Bromo-2'-deoxyguanosine can also be produced in the dermis of UV-B irradiated mice, and the extract of Coprinus comatus significantly reduces its level. 8-Bromo-2'-deoxyguanosine finds applications in studies related to inflammatory diseases, diabetes, hepatocellular carcinoma, and UV-B induced skin inflammation .
    8-Bromo-2'-deoxyguanosine
  • HY-W583212
    Zn(II) Mesoporphyrin IX

    ZnMP

    		 Biochemical Assay Reagents Heme Oxygenase (HO) Inflammation/Immunology
    Zn (II) Mesoporphyrin IX (ZnMP) is a heme oxygenase inhibitor with photochemical substrate activity. Zn (II) Mesoporphyrin IX specifically inhibits the activity of bone marrow heme oxygenase. In vitro, Zn (II) Mesoporphyrin IX inhibits the growth of erythroid and myeloid progenitor cells in rabbit bone marrow, and blocks the rhG-CSF-induced mobilization of these progenitor cells into the peripheral blood, exhibiting toxicity to hematopoietic growth and progenitor cell production in rabbits. Zn (II) Mesoporphyrin IX undergoes irreversible photochemical decomposition conforming to first-order kinetic characteristics when irradiated with UV-B in 95% ethanol solution. Zn (II) Mesoporphyrin IX can be used in hematopoietic regulation research, but its photolability and toxic effects on the hematopoietic system require attention .
    Zn(II) Mesoporphyrin IX
  • HY-Y1129
    3-Hydroxypyridine

    		Photosensitizer Apoptosis Inflammation/Immunology
    3-Hydroxypyridine is a compound that can be isolated from bamboo grass. As an endogenous photosensitizer present in human skin, 3-hydroxypyridine can mediate oxidative stress, proliferation inhibition and apoptosis of skin cells through UVA/UVB excitation .
    3-Hydroxypyridine
  • HY-W743654
    Capsorubin

    		Apoptosis Cancer
    Capsorubin is a carotenoid found in peppers with multiple biological activities. Capsorubin (167 μM) inhibits lipid peroxidation induced by 2,2'-azobis(2,4-dimethylvaleronitrile) (AMVN) in vitro. Capsorubin (1 μM) reduces UVB-induced DNA strand breaks and apoptosis in human dermal fibroblasts. Capsorubin also inhibits Epstein-Barr virus early antigen (EBV-EA) activation induced by phorbol 12-myristate 13-acetate in Raji cells, a marker of tumorigenesis.
    Capsorubin
  • HY-N0181A
    Lumisterol

    9β,10α-Ergosterol

    		 Endogenous Metabolite Metabolic Disease
    Lumisterol (9β,10α-Ergosterol), a steroid compound, is the (9β,10α)-stereoisomer of Ergosterol (HY-N0181). Lumisterol is a photoprotective agent against UVB-induced DNA damage and anti-proliferative activities .
    Lumisterol
  • HY-B0929
    Octisalate

    Octyl salicylate; 2-Ethylhexyl salicylate

    		 Environmental Pollutants Biochemical Assay Reagents Others
    Octisalate (Octyl salicylate) is an organic compound with high lipophilicity, which is used in sunscreens and cosmetics that absorbs UVB rays .
    Octisalate
  • HY-W020044R
    DL-alpha-Tocopherol (Standard)
    Maximum Cited Publications
    7 Publications Verification

    DL-α-Tocopherol (Standard)

    		 Reference Standards Ferroptosis DNA/RNA Synthesis Apoptosis Cancer
    DL-alpha-Tocopherol (Standard) is the analytical standard of DL-alpha-Tocopherol. This product is intended for research and analytical applications. DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB .
    DL-alpha-Tocopherol (Standard)
  • HY-113326
    Phytoene

    trans-Phytoene

    		 Reactive Oxygen Species (ROS) Cancer
    Phytoene (trans-Phytoene) is a carotene pigment. Phytoene is the precursor of all carotenoids. Phytoene is the predominant PT isomer in most carotenogenic organisms. Phytoene can delay the skin tumors appearance and reduce their number in mice that are induced the tumors with UV-B light. Phytoene leads to protection against oxidative stress and malignant transformation. Phytoene inhibits the proliferation of breast cancer cells .
    Phytoene
  • HY-167740
    Glycerophosphoinositol (lysine)

    GroPIns (lysine)

    		 Endogenous Metabolite Inflammation/Immunology
    Glycerophosphoinositol (GroPIns) lysine is a phospholipid metabolite that possesses anti-dandruff, anti-inflammatory, and anti-aging activities; it significantly suppresses UVB-induced PGE secretion in NHEK keratinocytes.
    Glycerophosphoinositol (lysine)
  • HY-A0087R
    Octocrylene (Standard)

    		Biochemical Assay Reagents Reference Standards PPAR Estrogen Receptor/ERR Cytochrome P450 Others
    Octocrylene (Standard) is the analytical standard of Octocrylene. This product is intended for research and analytical applications. Octocrylene is an organic ultraviolet (UV) filter which absorbs mainly UVB radiation and short UVA wavelengths. Octocrylene has the potential for using in various cosmetic products to either provide an appropriate sun protection factor in sunscreen products or to protect cosmetic formulations from UV radiation .
    Octocrylene (Standard)
  • HY-B1234R
    Octinoxate (Standard)

    Octyl methoxycinnamate (Standard)

    		 Reference Standards Androgen Receptor Estrogen Receptor/ERR Others
    Octinoxate (Standard) is the analytical standard of Octinoxate. This product is intended for research and analytical applications. Octinoxate (Octyl methoxycinnamate) is an organic compound that is an ingredient in some sunscreens and lip balms, primarily used is in sunscreens and other cosmetics to absorb UV-B rays from the sun, protecting the skin from damage and can be used to reduce the appearance of scars. Octinoxate also has a complex androgenic and estrogenic effect .
    Octinoxate (Standard)
  • HY-W743654R
    Capsorubin (Standard)

    		Apoptosis Reference Standards Cancer
    Capsorubin (Standard) is the analytical standard of Capsorubin. This product is intended for research and analytical applications. Capsorubin is a carotenoid found in peppers with multiple biological activities. Capsorubin (167 μM) inhibits lipid peroxidation induced by 2,2'-azobis(2,4-dimethylvaleronitrile) (AMVN) in vitro. Capsorubin (1 μM) reduces UVB-induced DNA strand breaks and apoptosis in human dermal fibroblasts. Capsorubin also inhibits Epstein-Barr virus early antigen (EBV-EA) activation induced by phorbol 12-myristate 13-acetate in Raji cells, a marker of tumorigenesis.
    Capsorubin (Standard)
  • HY-W011889
    Actinoquinol

    		Biochemical Assay Reagents Others
    Actinoquinol is a UVB absorber that can be helpful for the human eye in the defence against photooxidative and other oxidative processes .
    Actinoquinol
  • HY-B0929R
    Octisalate (Standard)

    Octyl salicylate (Standard); 2-Ethylhexyl salicylate (Standard)

    		 Biochemical Assay Reagents Reference Standards Others
    Octisalate (Standard) is the analytical standard of Octisalate. This product is intended for research and analytical applications. Octisalate is an organic compound used in sunscreens and cosmetics that absorbs UVB rays.
    Octisalate (Standard)
  • HY-U00265
    3-CPs

    3-Carbethoxypsoralen; 3-Ethoxycarbonylpsoralen

    		 Bacterial Infection
    3-CPs is a monofunctional furanocoumarin and a photoprotective agent targeting Staphylococcus aureus DNA, possessesing anti-UVB lethal activity. 3-CPs competitively intercalates into DNA, forming exclusively 4',5'-furan-side mono-adducts upon UVB irradiation, and irreversibly inhibits the formation of cyclobutane pyrimidine dimers. 3-CPs prevents UVB-induced DNA damage by preferentially binding to strong (AT)n sites within the DNA, without inducing lethal interstrand DNA cross-links; the limited number of mono-adducts it induces can be efficiently repaired by bacteria. 3-CPs holds potential for use in the development of photoprotective formulations for skin diseases, as well as in studies investigating bacterial DNA photodamage repair mechanisms and the optimization of photochemotherapy safety .
    3-CPs
  • HY-B1234A
    (E)-Octinoxate

    (E)-Octyl methoxycinnamate

    		 Estrogen Receptor/ERR Androgen Receptor Endocrinology
    (E)-Octinoxate is the isomer of Octinoxate (HY-B1234). Octinoxate is an organic compound that is an ingredient in some sunscreens and lip balms, primarily used is in sunscreens and other cosmetics to absorb UV-B rays from the sun, protecting the skin from damage and can be used to reduce the appearance of scars. Octinoxate also has a complex androgenic and estrogenic effect .
    (E)-Octinoxate
  • HY-N2007S
    Veratric acid-d6

    3,4-Dimethoxybenzoic acid-d6

    		 Isotope-Labeled Compounds COX Reactive Oxygen Species (ROS) Cardiovascular Disease Inflammation/Immunology
    Veratric acid-d6 is deuterium labeled Veratric acid. Veratric acid (3,4-Dimethoxybenzoic acid) is an orally active phenolic compound derived from vegetables and fruits, has antioxidant and anti-inflammatory activities . Veratric acid also acts as a protective agent against hypertension-associated cardiovascular remodelling . Veratric acid reduces upregulated COX-2 expression, and levels of PGE2, IL-6 after UVB irradiation .
    Veratric acid-d6
  • HY-N1151
    Thunberginol C

    		Bacterial Cholinesterase (ChE) MMP TNF Receptor Infection Neurological Disease Inflammation/Immunology
    Thunberginol C is an orally active, selective, and non-competitive inhibitor of AChE and BChE, with IC50 values of 41.96 and 42.36 μM, respectively. Thunberginol C exerts cytoprotective, pro-collagen type I restorative, MMP-1 inhibitory, hyaluronic acid restorative, anti-photoaging effects in skin cells. Thunberginol C exerts neuroprotective, anxiolytic, TNF-α inhibitory, neuroinflammation inhibitory, and oxidative stress inhibitory effects. Thunberginol C can be used for the research of Alzheimer’s disease, UVB-induced skin photoaging, allergic reactions, oral bacterial infections, and stress-induced anxiety .
    Thunberginol C
  • HY-W419643
    Drometrizole trisiloxane

    		Biochemical Assay Reagents Others
    Drometrizole trisiloxane is a photostable, oil-soluble chemical UVB and UVA filter with two absorption peaks, one at 303 nm (UVB) and the other at 344 nm (UVA). Drometrizole trisiloxane can be used in cosmetics to absorb ultraviolet radiation .
    Drometrizole trisiloxane
  • HY-137989
    Voriconazole N-oxide

    Voriconazole oxynitride

    		 Fungal Infection
    Voriconazole N-oxide (Voriconazole oxynitride) is a potent antifungal agent. Voriconazole N-oxide has phototoxicity and photocarcinogenicity. Voriconazole N-oxide does not sensitize keratinocytes to ultraviolet B (UVB) .
    Voriconazole N-oxide
  • HY-N3612
    Communic acid

    (+)-Communic acid

    		 Bacterial Akt MMP Infection Inflammation/Immunology
    Communic acid ((+)-Communic acid) is a natural compound isolated from the branches of Platycladus orientalis. Communic acid displays minimum inhibitory concentration of 31 μM and IC50 of 15 μM against M. tuberculosis H37Ra.Communic acid exhibits protective effects against UVB-induced skin aging .
    Communic acid
  • HY-N12150
    Isozedoarondiol

    		MMP Others
    Isozedoarondiol can be isolated from the rhizomes of Curcuma xanthorrhiza Roxb. Isozedoarondiol inhibits MMP-1 expression in UVB-treated human keratinocytes .
    Isozedoarondiol
  • HY-N6641R
    Monascin (Standard)

    		Reference Standards Keap1-Nrf2 PPAR Inflammation/Immunology Cancer
    Monascin (Standard) is the analytical standard of Monascin. This product is intended for research and analytical applications. Monascin is a kind of azaphilonoid pigments extracted from Monascus pilosus-fermented rice (red-mold rice). Monascin also exhibits anti-tumor-initiating activity and anti-inflammatory activity with oral administration. Monascin inhibits the activation of NOR 1 (an NO donor). Monascin is a Nrf2 activator and PPARγ agonist .
    Monascin (Standard)
  • HY-116145
    MHY884

    		Tyrosinase NF-κB Inflammation/Immunology
    MHY884 is a tyrosinase inhibitor that suppresses UVB-induced activation of NF-κB signaling pathway through the downregulation of oxidative stress. MHY884 suppresses oxidative stress in the melanoma cells and attenuates UVB-induced oxidative stress, resulting in reduced NF-κB activity in irradiated mice. MHY884 is promising for research of UVB-induced skin damage .
    MHY884
  • HY-W419643R
    Drometrizole trisiloxane (Standard)

    		Biochemical Assay Reagents Reference Standards Others
    Drometrizole trisiloxane (Standard) is the analytical standard of Drometrizole trisiloxane. This product is intended for research and analytical applications. Drometrizole trisiloxane is a photostable, oil-soluble chemical UVB and UVA filter with two absorption peaks, one at 303 nm (UVB) and the other at 344 nm (UVA). Drometrizole trisiloxane can be used in cosmetics to absorb ultraviolet radiation .
    Drometrizole trisiloxane (Standard)
  • HY-170975
    UG-650

    		VD/VDR Cancer
    UG-650 is a non-Gemini analog of UVB1 that combines the structural features of UVB1 and MC 1288. UG-650 can bind to the vitamin D receptor (VDR) and inhibit the proliferation of MCF-7 cells and the migration of MC3T3-E1 cells .
    UG-650
  • HY-W749966
    Octocrylene-d10

    		Isotope-Labeled Compounds Metabolic Disease
    Octocrylene-d10 is the deuterium labeled Octocrylene. Octocrylene is an organic ultraviolet (UV) filter which absorbs mainly UVB radiation and short UVA wavelengths .
    Octocrylene-d10
  • HY-109655R
    Ethylhexyl triazone (Standard)

    Octyl triazone (Standard)

    		 Biochemical Assay Reagents Reference Standards Others
    Ethylhexyl triazone (Standard) is the analytical standard of Ethylhexyl triazone. This product is intended for research and analytical applications. Ethylhexyl triazone is an approved ultraviolet-B (UV-B) chemical filter for commercial sunscreens.
    Ethylhexyl triazone (Standard)
  • HY-B0897R
    Bisoctrizole (Standard)

    		Reference Standards Biochemical Assay Reagents Others
    Bisoctrizole (Standard) is the analytical standard of Bisoctrizole (HY-B0897). This product is intended for research and analytical applications. Bisoctrizole is a broad-spectrum UVA/UVB absorber that belongs to the benzotriazole class of compounds. Bisoctrizole absorbs UV light through hydroxyphenyl groups, causing reversible electronic transitions, thereby converting light energy into heat energy, inhibiting UV-induced material or skin damage. Bisoctrizole is highly efficient in capturing UVA (320-400 nm) and some UVB (280-320 nm) radiation. Bisoctrizole delays the photodegradation of materials such as silicones, improving their UV aging resistance or enhancing the photoprotective ability of sunscreen products .
    Bisoctrizole (Standard)
  • HY-W020044S1
    DL-alpha-Tocopherol-d9

    		Ferroptosis Others
    DL-alpha-Tocopherol-d9 is the deuterium labeled DL-alpha-Tocopherol . DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB .
    DL-alpha-Tocopherol-d9
  • HY-W020044S
    DL-alpha-Tocopherol-13C3

    		Isotope-Labeled Compounds Ferroptosis Others
    DL-alpha-Tocopherol- 13C3 is the 13C-labeled DL-alpha-Tocopherol. DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB .
    DL-alpha-Tocopherol-13C3
  • HY-109654R
    Ensulizole (Standard)

    		Reference Standards Reactive Oxygen Species (ROS) Metabolic Disease
    Ensulizole (Standard) is the analytical standard of Ensulizole. This product is intended for research and analytical applications. Ensulizole is a sulfonated UV absorber and can intense UVB and partial UVA absorption. Ensulizole can damage the DNA through the generation of reactive oxygen species (ROS) upon UV or sunlight irradiation .
    Ensulizole (Standard)

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