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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
48 Results for "
adiponectin
" in MedChemExpress (MCE) Product Catalog:
Products (48)
48 Results for "adiponectin" in MCE Product Catalog:
43
43 Publications Verification
Target:
Research Areas:
AdipoRon is an orally active adiponectin receptor (AdipoR) agonist, binding to AdipoR1 and AdipoR2 with Kds of 1.8 and 3.1 μM, respectively.
4
2
2
2 Cited Publications
Cat. No.: HY-P7461
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ADIPOQ; Adipocyte, C1Q And Collagen Domain Containing; Prev. ACDC; Adipose Specific Collagen-Like Factor; adiponectin; Gelatin-Binding Protein 28; ACRP30; Gelatin-Binding Protein; GBP28; adiponectin Precursor; ApM1; ADIPQTL1; Adipose Most Abundant Gene Tr
Species:
Mouse
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-N0755
CAS No.: 17306-46-6
Category:
Rhus succedanea Flavonoids Anacardiaceae Extract Flavones Plants Disease Research Fields Endocrinology Cancer
Target:
1
1 Cited Publications
Synonyms: rel-Cianidanol; rel-Catechuic acid
Category:
Cardiovascular Disease Neurological Disease Plants Camellia sinensis (L.) O. Ktze. Theaceae Extract Infection Phenols Polyphenols Disease Research Fields Inflammation/Immunology
Target:
1
1 Cited Publications
Cat. No.: HY-N0853A
CAS No.: 18674-16-3
Synonyms: Alisol A 24-monoacetate; Alisol A monoacetate
1
1 Cited Publications
Cat. No.: HY-P70504
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ADIPOQ; Adipocyte, C1Q And Collagen Domain Containing; Prev. ACDC; Adipose Specific Collagen-Like Factor; adiponectin; Gelatin-Binding Protein 28; ACRP30; Gelatin-Binding Protein; GBP28; adiponectin Precursor; ApM1; ADIPQTL1; Adipose Most Abundant Gene Tr
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P7127
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ADIPOQ; Adipocyte, C1Q And Collagen Domain Containing; Prev. ACDC; Adipose Specific Collagen-Like Factor; adiponectin; Gelatin-Binding Protein 28; ACRP30; Gelatin-Binding Protein; GBP28; adiponectin Precursor; ApM1; ADIPQTL1; Adipose Most Abundant Gene Tr
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P7129
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ADIPOQ; Adipocyte, C1Q And Collagen Domain Containing; Prev. ACDC; Adipose Specific Collagen-Like Factor; adiponectin; Gelatin-Binding Protein 28; ACRP30; Gelatin-Binding Protein; GBP28; adiponectin Precursor; ApM1; ADIPQTL1; Adipose Most Abundant Gene Tr
Species:
Mouse
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P7358
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ADIPOQ; Adipocyte, C1Q And Collagen Domain Containing; Prev. ACDC; Adipose Specific Collagen-Like Factor; adiponectin; Gelatin-Binding Protein 28; ACRP30; Gelatin-Binding Protein; GBP28; adiponectin Precursor; ApM1; ADIPQTL1; Adipose Most Abundant Gene Tr
Species:
Mouse
Source:
E. coli
Synonyms: Elastase Inhibitor III
Target:
Research Areas:
MeOSuc-AAPV-CMK (Elastase Inhibitor III) is an elastase inhibitor that simultaneously inhibits Cathepsin G and Proteinase 3. MeOSuc-AAPV-CMK blocks the shedding of FcgRIIIb on the surface of human neutrophils. MeOSuc-AAPV-CMK reverses the elastase-mediated reduction in proinflammatory cytokine production by immune cells, partially restores IL-1β levels in immune cell co-culture systems, and prevents elastase-mediated adiponectin cleavage .
Research Areas:
Synonyms: ZGN-1061
Target:
Research Areas:
Aclimostat (ZGN-1061) is a methionine aminopeptidase 2 (MetAP2) inhibitor. Aclimostat exhibits anti-obesity, anti-diabetic and ovarian cancer-related activities, and does not readily distribute to the central nervous system. Aclimostat acts on the active site of MetAP2 via irreversible covalent binding, and blocks enzyme activity through interactions with His231 and His339. Aclimostat regulates gene expression, reduces fat mass, plasma glucose, insulin levels, LDL-C, hs-CRP and leptin levels, while increasing adiponectin levels. Aclimostat can be used in research related to type 2 diabetes, overweight, obesity and ovarian cancer .
Cat. No.: HY-17445
CAS No.: 331741-94-7
Synonyms: BMS-298585
Target:
Research Areas:
Muraglitazar (BMS-298585) is an orally active non-thiazolidinedione oxybenzylglycine dual-target PPARα/PPARγ agonist, with an IC50 of 0.25 μM and an EC50 of 0.32 μM against human PPARα, and an IC50 of 0.19 μM and an EC50 of 0.11 μM against human PPARγ. Muraglitazar regulates lipid homeostasis, enhances peripheral insulin sensitivity, and improves β-cell function. Muraglitazar reduces levels of blood glucose, insulin, triglycerides and free fatty acids, normalizes adiponectin and corticosterone levels, promotes cholesterol efflux, reduces hepatic lipid content, regulates body weight, prevents hyperglycemia, and improves glucose tolerance. Muraglitazar can be used in research related to type 2 diabetes and dyslipidemia .
Cat. No.: HY-N13250
Target:
Research Areas:
AdipoR agonist 1 (Compound 112254) is an agonist for adiponectin receptor (AdipoR), which activates the transcriptional regulators like peroxisome proliferator-activated receptors (PPARs), peroxisome proliferator-activated receptor gamma coactivator 1α (PGC-1α), sirtuin 1 (SIRT1), and adenylate-activated protein kinase (AMPK). AdipoR agonist 1 is utilized in preventive doping research .
Synonyms: rel-Cianidanol (Standard); rel-Catechuic acid (Standard)
Target:
Research Areas:
SB 220025 is a reversible, orally active, cell-permeable, ATP-competitive and selective human p38 MAPK inhibitor (IC50 = 60 nM). SB 220025 also inhibits p56 Lck and PKC with IC50 values of 3.5 and 2.89 µM, respectively. SB 220025 inhibits the expression of IL-8 gene in response to globular adiponectin (gAd), reduces inflammatory cytokine production and inhibits angiogenesis. SB 220025 effectively prevents the progression of arthritis in a chronic inflammatory disease model and can be used in the study of inflammation .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
