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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
147 Results for "
chalcone
" in MedChemExpress (MCE) Product Catalog:
Products (147)
147 Results for "chalcone" in MCE Product Catalog:
19
19 Publications Verification
Cat. No.: HY-N0279
CAS No.: 18956-16-6
Synonyms: Cardamomin; Alpinetin chalcone
9
9 Cited Publications
Cat. No.: HY-N0269
CAS No.: 34221-41-5
8
8 Cited Publications
Cat. No.: HY-N3007
CAS No.: 73692-50-9
Category:
Plants Endogenous metabolite Human Gut Microbiota Metabolites other families Flavonoids Chalcones Phenols Polyphenols Disease Research Fields Inflammation/Immunology
Target:
7
4
Category:
Plants Dihydrochalcones Sweeteners Food Research other families Flavonoids Phenols Polyphenols Disease Research Fields Inflammation/Immunology
Target:
4
4 Cited Publications
Cat. No.: HY-N1378
CAS No.: 19309-14-9
Synonyms: (E)-Cardamomin; (E)-Alpinetin chalcone
Category:
Neurological Disease Alpinia katsumadai Hayata Plants Flavonoids Chalcones Phenols Polyphenols Disease Research Fields Cancer Zingiberaceae
Target:
4
4 Cited Publications
Cat. No.: HY-N2445
CAS No.: 37308-75-1
3
Category:
Plants Endogenous metabolite Flavonoids Chalcones Monophenols Leguminosae Phenols Disease Research Fields Glycyrrhiza uralensis Fisch. Inflammation/Immunology
Target:
3
3
Category:
3
3 Cited Publications
Cat. No.: HY-N5106
CAS No.: 37951-13-6
Category:
other families Flavonoids Chalcones Monophenols Phenols Plants Disease Research Fields Cancer
Target:
2
2 Cited Publications
Category:
Flavonoids Chalcones Rutaceae Plants Disease Research Fields Inflammation/Immunology Citrus
Target:
2
2 Cited Publications
Cat. No.: HY-N2208
CAS No.: 56083-03-5
2
2 Cited Publications
Cat. No.: HY-N1745A
CAS No.: 112408-67-0
2
1
1 Cited Publications
Synonyms: (E/Z)-Benzylideneacetophenone
1
1 Cited Publications
Cat. No.: HY-N12422
Category:
Target:
1
1
1 Cited Publications
Cat. No.: HY-W082785A
CAS No.: 24533-47-9
Target:
TNF Receptor Interleukin Related Toll-like Receptor (TLR) NF-κB NOD-like Receptor (NLR) Apoptosis Caspase Bcl-2 Family Reactive Oxygen Species (ROS)
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology
L6H21, a Chalcone (HY-121054) derivative, is an orally active, potent and specific myeloid differentiation 2 (MD-2) inhibitor. L6H21 directly binds to MD-2 protein with a high affinity and low KD value of 33.3 μM, blocking the formation of the LPS-TLR4/MD-2 complex. L6H21 inhibits LPS-induced expression of TNF-α and IL-6 in RAW264.7 macrophages, with IC50 values of 6.58 and 8.59 μM, respectively. L6H21 can be used for alcoholic liver disease, metabolic disturbance and neuroinflammation research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
