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Results for "

parasitic

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (2) Akt (1) Angiotensin Receptor (1) Angiotensin-converting Enzyme (ACE) (1) Antibiotic (34) Apoptosis (8) Autophagy (5) Bacterial (18) Biochemical Assay Reagents (1) Calcium Channel (1) Cathepsin (2) Cholinesterase (ChE) (2) Cytochrome P450 (3) Dihydrofolate reductase (DHFR) (1) Drug Derivative (1) Drug Intermediate (1) Drug Isomer (1) Drug Metabolite (1) Endogenous Metabolite (10) Environmental Pollutants (7) Exosomes (3) Filovirus (2) Fluorescent Dye (1) Fungal (12) GABA Receptor (1) HDAC (3) Herbicide (1) Influenza Virus (2) Insecticide (1) Integrin (1) Interleukin Related (3) Isotope-Labeled Compounds (9) L-Selectin (1) mAChR (5) Mitochondrial Metabolism (2) mRNA (2) mTOR (1) Na+/H+ Exchanger (NHE) (3) nAChR (10) NF-κB (2) NO Synthase (1) p38 MAPK (1) Parasite (122) Phosphatase (1) Phytohormone (1) PI3K (3) PI4K (1) Reactive Oxygen Species (ROS) (4) Reference Standards (27) SARS-CoV (3) SHP1 (1) STAT (9) TNF Receptor (1) TrxR (1) VD/VDR (1) Wnt (3) γ-Glutamyl Transferase (GGT) (2)
By Research Areas:	Cancer (41) Cardiovascular Disease (4) Infection (124) Inflammation/Immunology (28) Metabolic Disease (8) Neurological Disease (9)
Oligonucleotides:	Chemokine & Receptors (1) mRNA (2) Interleukin & Receptors (1)

155

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

GMP Molecules

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0497

Niclosamide Maximum Cited Publications 40 Publications Verification BAY2353	Environmental Pollutants Antibiotic Parasite STAT	Infection Cancer
Niclosamide (BAY2353) is an orally active antihelminthic agent used in parasitic infection research . Niclosamide is a STAT3 inhibitor with an IC₅₀ of 0.25 μM in HeLa cells . Niclosamide has biological activities against cancer, inhibits DNA replication in Vero E6 cells .

HY-B0217

Nitazoxanide 10+ Cited Publications NTZ; NSC 697855	Parasite Influenza Virus Autophagy	Infection Cancer
Nitazoxanide (NTZ), an anthelmintic agent, exhibits a broad spectrum of activities against a wide variety of helminths, protozoa, and enteric bacteria infecting animals and humans. Nitazoxanide inhibits Giardia lamblia trophozoite proliferation in axenic culture with an IC₅₀ of 2.4 μM . Nitazoxanide can be used for the research of *parasitic* gastroenteritis. Nitazoxanide shows anti-Japanese encephalitis virus (JEV) activity in a mouse model .

HY-129038

GR24 1 Publications Verification Strigolactone GR24	Biochemical Assay Reagents	Others
(Rac)-GR24 (Strigolactone GR24) is a plant hormone analog. (Rac)-GR24 can mimic the natural germination stimulus of parasitic plant seeds, promoting seed germination in the absence of host plants, thereby reducing the number of parasitic seeds in the soil. (Rac)-GR24 can be used in agricultural research .

HY-B0956

Paromomycin sulfate 4 Publications Verification Aminosidine sulfate	Antibiotic Parasite Bacterial	Infection
Paromomycin (Aminosidine) sulfate, a neomycin (HY-B0470) derivative, is a broad spectrum aminoglycoside antibiotic with amebicidal and bactericidal effects. Paromomycin sulfate prematures termination of translation of mRNA and inhibits protein synthesis by specifically binds to the RNA oligonucleotide at the A site of bacterial 30S ribosomes. Paromomycin sulfate can be used for the research of bacterial and parasitic infections .

HY-N2364

Arecoline 5 Publications Verification	mAChR nAChR	Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Arecoline, a naturally brain-penetrant and orally active occurring psychoactive alkaloid, is a partial agonist of nicotinic and muscarinic acetylcholine receptor. Arecoline exhibits stimulation, alertness, anxiolysis and anti-parasitic effects. Arecoline also can induce oxidative stress .

HY-12651

Primaquine diphosphate 5+ Cited Publications Primaquine phosphate; Primaquine bisphosphate	Parasite	Infection Cancer
Primaquine diphosphate is a potent antimalaria agent and a potent gametocytocide in falciparum malaria. Primaquine diphosphate prevents relapse in vivax and ovale malaria .

HY-50730

Asparagusic acid 4 Publications Verification	Parasite Endogenous Metabolite	Infection
Asparagusic acid is a sulfur-containing flavor component produced by Asparagus officinalis Linn., with anti-parasitic effect. Asparagusic acid is a plant growth inhibitor .

HY-12640

Pyrantel pamoate 4 Publications Verification Pyrantel embonate	Parasite nAChR Antibiotic	Infection
Pyrantel pamoate (Pyrantel embonate) is an orally active anthelmintic and an agonist of the nicotinic acetylcholine receptor (nAChR). Pyrantel pamoate can cause spasmodic muscle paralysis in parasites. Pyrantel pamoate can be used in the study of parasitic infections such as ascariasis, hookworm infections, intestinal worms (pinworm infections), trichinosis and trichinosis .

HY-B0489

Arecoline hydrobromide 5 Publications Verification methyl 1,2,5,6-tetrahydro-1-methyl-3-pyridinecarboxylate hydrobromide	mAChR nAChR	Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Arecoline hydrobromide, a naturally brain-penetrant and orally active occurring psychoactive alkaloid, is a partial agonist of nicotinic and muscarinic acetylcholine receptor. Arecoline hydrobromide exhibits stimulation, alertness, anxiolysis and anti-parasitic effects. Arecoline hydrobromide also can induce oxidative stress .

HY-17596

Closantel 10+ Cited Publications	Parasite	Infection
Closantel is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC₅₀ of 1.6 μM and a K_i of 468 nM. Closantel inhibits the O. volvulus L3 to L4 molt of developing .

HY-B0357

Diclazuril 2 Publications Verification R-64433	Parasite Antibiotic	Infection
Diclazuril (R-64433), a benzeneacetonitrile derivative, is a potent and orally active anticoccidial agent. Diclazuril can be used for the research of certain infectious and parasitic diseases, including coccidiosis, acute toxoplasmosis, equine protozoal pyoencephalitis (EPM) et.al .

HY-B0937A

Amprolium hydrochloride	Parasite	Infection
Amprolium hydrochloride is an anti-parasitic drug that's kind of taken orally, and it acts as an antagonist to thiamine in intestinal absorption .

HY-14932

Pafuramidine 1 Publications Verification DB289	Parasite Antibiotic	Infection Neurological Disease
Pafuramidine (DB289) is an orally active proagent of Furamidine (HY-110137A). Pafuramidine is a potent anti-parasitic agent, can be used to research trypanosomiasis, Pneumocystis pneumonia and malaria .

HY-121054

Chalcone 1 Publications Verification (E/Z)-Benzylideneacetophenone	Bacterial Parasite	Inflammation/Immunology Cancer
Chalcone is isolated from Glycyrrhiza uralensis and used to synthesize chalcone derivatives. Chalcone derivatives possess varied biological and pharmacological activity, including anti-inflammatory, antioxidative, antibacterial, anticancer, and anti-parasitic activities .

HY-W016586

Acivicin 2 Publications Verification AT-125; U-42126	Parasite γ-Glutamyl Transferase (GGT)	Infection Cancer
Acivicin (AT-125), a natural product produced by Streptomyces sviceus is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin can across the blood-brain barrier and has anti-cancer, anti-parasitic properties .

HY-W016586A

Acivicin hydrochloride 2 Publications Verification AT-125 hydrochloride; U-42126 hydrochloride	Parasite	Infection Cancer
Acivicin hydrochloride (AT-125 hydrochloride), a natural product produced by Streptomyces sviceus, is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin hydrochloride can across the blood-brain barrier and has anti-cancer, anti-parasitic properties .

HY-W011517

2-Fluoroadenosine 2FA	Parasite	Infection
2-Fluoroadenosine (2FA) is a nucleoside analogue. 2-Fluoroadenosine has antiparasite activity with EC₅₀ value of 0.842 mM for Cryptosporidium parvum. 2-Fluoroadenosine has a highly specific structural basis for MtADK. 2-Fluoroadenosine is commonly used in the study of parasitic conditions .

HY-B0357S

Diclazuril-d4 R-64433-d₄	Isotope-Labeled Compounds Parasite Antibiotic	Infection
Diclazuril-d₄ is deuterium labeled Diclazuril. Diclazuril (R-64433), a benzeneacetonitrile derivative, is a potent and orally active anticoccidial agent. Diclazuril can be used for the research of certain infectious and parasitic diseases, including coccidiosis, acute toxoplasmosis, equine protozoal pyoencephalitis (EPM) et.al .

HY-N4302

Monensin Maximum Cited Publications 38 Publications Verification Monensin A	Exosomes Bacterial Apoptosis Antibiotic Parasite Na+/H+ Exchanger (NHE) Fungal Wnt	Infection Cancer
Monensin (Monensin A), an orally active antibiotic, is an ionophore that mediates Na ⁺/H ⁺ exchange. Monensin is a potent Wnt signaling inhibitor. Monensin causes a marked enlargement of the multivesicular bodies (MVBs) and regulates exosome secretion. Monensin can be used for bacterial, fungal, and parasitic infections research, and shows anticancer effects .

HY-12912

KDU691	PI4K Parasite	Infection
KDU691, an imidazopyrazine with potent anti-parasitic activity against blood stage schizonts, gametocytes and liver stages, is a Plasmodium PI4K inhibitor. KDU691 selectively inhibits dihydroartemisinin-pretreated Plasmodium falciparum ring-stage parasites .

HY-17596A

Closantel sodium 10+ Cited Publications	Parasite	Infection
Closantel sodium is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel sodium is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC₅₀ of 1.6 μM and a K_i of 468 nM. Closantel sodium inhibits the O. volvulus L3 to L4 molt of developing .

HY-18715

Ornidazole (Levo-) (S)-Ornidazole; Levornidazole	Bacterial Parasite GABA Receptor Drug Isomer	Infection Neurological Disease
Levo-ornidazole ((S)-Ornidazole) is the L-isomer of Ornidazole. Ornidazole (Levo-) increases GAD 65/67 expression and decreases brain Glu/GABA ratio. Ornidazole (Levo-) has a mild sedative effect. Levo-ornidazole can be used in the research of anti-anaerobic and anti-parasitic agents .

HY-107771

Fluensulfone MCW-2	Environmental Pollutants Parasite	Cancer
Fluensulfone is a new nematicide for chemical control of plant parasitic nematodes.

HY-P2779

Microsomal aminopeptidase, Microorganism	Endogenous Metabolite	Metabolic Disease
Microsomal aminopeptidase, Microorganism is first reported from C. elegans. The Microsomal aminopeptidase, Microorganism is beneficial for the development of molecular vaccines against parasitic nematodes .

HY-121241

Dehydroemetine	Parasite	Infection
Dehydroemetine is an orally active antiparasitic agent. Dehydroemetine can inhibit parasites such as Entamoeba histolytica, and it can also be used in the research of parasitic diseases like visceral leishmaniasis .

HY-P2759

Thioredoxin reductase TrxR	TrxR	Infection Cardiovascular Disease Inflammation/Immunology Cancer
Thioredoxin reductase (TrxR) is a selenoprotein that plays a central role in cellular redox homeostasis by utilizing highly reactive selenocysteine (Sec) residues exposed to solvents at its active site. Thioredoxin reductase can be used for the study of diverse diseases, from rheumatoid arthritis and ischemia to cancer and parasitic infections .

HY-B0945

Nitromide 1 Publications Verification 3,5-Dinitrobenzamide	Parasite	Infection
Nitromide is an anti-parasitic agent.

HY-W020785

Fosthiazate	Environmental Pollutants Cholinesterase (ChE)	Others
Fosthiazate is a broad-spectrum nematicide against various plant parasitic nematodes, including Meloidogyne spp., Globodera spp., and Pratylenchus spp., through inhibiting the synthesis of acetylcholinesterase .

HY-129671

Polypodine B 5β-Hydroxyecdysterone	Parasite Fungal	Infection
Polypodine B is a natural ecdysone ester isolated from the bark of Dacrydium intermedium. Polypodine B significantly inhibits the activity of *Acanthamoeba castellani. Polypodine B has moderate antifungal* activity. Polypodine B can be used for research on parasitic diseases and fungal infections .

HY-N15133

Solanacol (-)-Solanacol	Drug Derivative	Others
Solanacol ((-)-Solanacol) is a strigolactone germination stimulant that can be isolated from tobacco (Nicotiana tabacum L.). Solanacol stimulates the germination of root parasitic weed seeds .

HY-17532

Haloxon	Parasite	Infection
Haloxon is an anti-parasitic agent. Haloxon can be used for the research of infections of Parascaris equorum, Oxyuris equi and Strongylus vulgaris. Haloxon also can be used in control of ascarids and hookworms in domesticated animals in combination with Bidimazium .

HY-123305

5-Hydroxymebendazole	Parasite	Others
5-Hydroxymebendazole is the one metabolite of Benzimidazoles. Benzimidazoles are safe, broad-spectrum anthelmintic agents and are widely used for prevention and treatment of parasitic infections in food-producing animals .

HY-P990208

Anti-Mouse IL-9 Antibody (9C1)	Interleukin Related NF-κB Parasite	Infection Inflammation/Immunology Cancer
Anti-Mouse IL-9 Antibody (9C1) is an anti-mouse IL-9 IgG2a monoclonal antibody. Anti-Mouse IL-9 Antibody (9C1) can reduce the activation of NF-κB signaling pathway and decrease the infiltration of inflammatory cells. Anti-Mouse IL-9 Antibody (9C1) effectively reduces Th9 cell-mediated allergic reactions and anti-tumor effects. Anti-Mouse IL-9 Antibody (9C1) can be used for researches on inflammation, infection conditions and cancer such as parasitic infections, allergic reactions, breast cancer and osteosarcoma .

HY-W009213

3-Nitrophenyl disulfide Bis(3-nitrophenyl) disulfide; Nitrophenide	Parasite	Infection
3-Nitrophenyl disulfide (Bis(3-Nitrophenyl) disulfide) is an inhibitor of mannitol-1-phosphate dehydrogenase (M1PDH) with IC₅₀ of 3 μM. 3-Nitrophenyl disulfide has antiparasitic activity .

HY-N0924A

(±)-Stylopine hydrochloride 1 Publications Verification Tetrahydrocoptisine hydrochloride	Parasite	Inflammation/Immunology
(±)-Stylopine (Tetrahydrocoptisine) hydrochloride is an alkaloid compound originally isolated from Corydalis tubers that exhibits anti-inflammatory and anti-parasitic activities .

HY-125729

Ivermectin B1b	Parasite SARS-CoV	Infection
Ivermectin B1b is the minor component of Ivermectin. Ivermectin, a potent anti-parasitic agent, inhibits the replication of SARS-CoV-2 in cell culture .

HY-12651R

Primaquine diphosphate (Standard) Primaquine phosphate (Standard); Primaquine bisphosphate (Standard)	Reference Standards Parasite	Infection Cancer
Primaquine (diphosphate) (Standard) is the analytical standard of Primaquine (diphosphate). This product is intended for research and analytical applications. Primaquine diphosphate is a potent antimalaria agent and a potent gametocytocide in falciparum malaria. Primaquine diphosphate prevents relapse in vivax and ovale malaria .

HY-N15748

Pelorol (-)-Pelorol	Parasite	Infection
Pelorol ((-)-Pelorol) is a sesquiterpene found in the tropical marine sponge Dactylospongia elegans. Pelorol has weak antitrypanosomal activity with an IC₅₀ of 17.4 μg/mL and antiplasmodial activity against Plasmodium falciparum clones K1 and NF54 with IC₅₀ values of 786 ng/mL and 1911 ng/mL, respectively. Pelorol is promising for research of parasitic diseases, such as trypanosomiasis and malaria .

HY-12641

Pyrantel tartrate 1 Publications Verification	Parasite nAChR Antibiotic	Infection
Pyrantel tartrate is an orally active anthelmintic and an agonist of the nicotinic acetylcholine receptor (nAChR). Pyrantel tartrate can cause spasmodic muscle paralysis in parasites. Pyrantel tartrate can be used in the study of parasitic infections such as ascariasis, hookworm infections, intestinal worms (pinworm infections), trichinosis and trichinosis .

HY-P990201

Anti-Mouse L-Selectin/CD62L Antibody (Mel-14)	L-Selectin	Infection Metabolic Disease Inflammation/Immunology
Anti-Mouse L-Selectin/CD62L Antibody (Mel-14) is an anti-mouse L-Selectin/CD62L IgG2a monoclonal antibody. Anti-Mouse L-Selectin/CD62L Antibody (Mel-14) can significantly inhibit the migration of T cells and B cells. Anti-Mouse L-Selectin/CD62L Antibody (Mel-14) can block initial lymphocyte homing. Anti-Mouse L-Selectin/CD62L Antibody (Mel-14) can be used for researches on inflammation, metabolic and infection conditions such as diabetes and parasitic infections .

HY-108387

Morantel citrate	Parasite	Infection
Morantel citrate is a veterinary anthelmintic agent that inhibits parasitic infections in cattle, sheep and goats. Morantel citrate paralyzes the nervous system of the parasite, helping the animal expel the dead parasite from the body .

HY-123305S

5-Hydroxymebendazole-d3	Parasite Isotope-Labeled Compounds	Others
5-Hydroxymebendazole-d₃ is a deuterium labeled 5-Hydroxymebendazole. 5-Hydroxymebendazole is the one metabolite of Benzimidazoles .

HY-W973644

LY-266500	Mitochondrial Metabolism Parasite	Infection
LY-266500 is a succinyl CoA synthetase (SCS) specific inhibitor. LY-266500 has inhibitory effects on various parasites, such as Trypanosoma brucei brucei (IC₅₀ =0.6 μM) and Leishmania donovani (IC₅₀ =2.86 μM). LY-266500 can be used for research on parasitic infections .

HY-B0497B

Niclosamide monohydrate BAY2353 monohydrate	STAT Antibiotic Parasite	Infection Cancer
Niclosamide (BAY2353) monohydrate is an orally active antihelminthic agent used in parasitic infection research . Niclosamide monohydrate is a STAT3 inhibitor with an IC₅₀ of 0.25 μM in HeLa cells . Niclosamide monohydrate has biological activities against cancer, and inhibits DNA replication in Vero E6 cells .

HY-50730R

Asparagusic acid (Standard)	Parasite Endogenous Metabolite Reference Standards	Infection
Asparagusic acid (Standard) is the analytical standard of Asparagusic acid. This product is intended for research and analytical applications. Asparagusic acid is a sulfur-containing flavor component produced by Asparagus officinalis Linn., with anti-parasitic effect. Asparagusic acid is a plant growth inhibitor .

HY-12641A

Pyrantel	nAChR Parasite Antibiotic	Infection
Pyrantel is an orally active anthelmintic and an agonist of the nicotinic acetylcholine receptor (nAChR). Pyrantel can cause spasmodic muscle paralysis in parasites. Pyrantel can be used in the study of parasitic infections such as ascariasis, hookworm infections, intestinal worms (pinworm infections), trichinosis and trichinosis .

HY-B0489R

Arecoline hydrobromide (Standard) methyl 1,2,5,6-tetrahydro-1-methyl-3-pyridinecarboxylate hydrobromide (Standard)	Reference Standards mAChR nAChR	Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Arecoline hydrobromide (Standard) is the analytical standard of Arecoline hydrobromide. This product is intended for research and analytical applications. Arecoline hydrobromide, a naturally brain-penetrant and orally active occurring psychoactive alkaloid, is a partial agonist of nicotinic and muscarinic acetylcholine receptor. Arecoline hydrobromide exhibits stimulation, alertness, anxiolysis and anti-parasitic effects. Arecoline hydrobromide also can induce oxidative stress .

HY-N16123

Chloranthalactone C	Parasite	Infection
Chloranthalactone C (Compound 43), a lindenane-type sesquiterpenoid, is an antimalarial agent. Chloranthalactone C can be isolated from plant Chloranthus japonicas Sieb. Chloranthalactone C inhibits Chloroquine (HY-17589A)-resistant Plasmodium falciparum strain Dd2 growth. Chloranthalactone C can be used for parasitic infections research .

HY-B0217R

Nitazoxanide (Standard) NTZ (Standard); NSC 697855 (Standard)	Reference Standards Parasite Influenza Virus Autophagy	Infection Cancer
Nitazoxanide (Standard) is the analytical standard of Nitazoxanide. This product is intended for research and analytical applications. Nitazoxanide (NTZ), an anthelmintic agent, exhibits a broad spectrum of activities against a wide variety of helminths, protozoa, and enteric bacteria infecting animals and humans. Nitazoxanide inhibits Giardia lamblia trophozoite proliferation in axenic culture with an IC₅₀ of 2.4 μM . Nitazoxanide can be used for the research of *parasitic* gastroenteritis. Nitazoxanide shows anti-Japanese encephalitis virus (JEV) activity in a mouse model .

HY-115550

Chalcone 4 hydrate	Parasite	Infection
Chalcone 4 hydrate is an anti-parasitic agent. Chalcone 4 hydrate inhibits the growth and proliferation of Babesia and Theileria in vitro. Chalcone 4 hydrate reduces the viability of mammalian fibroblasts and kidney cells in vitro. Chalcone 4 hydrate can be used for the research of parasitic infections .

Cat. No.	Product Name

HY-L082

Antiparasitic Compound library

637 compounds

A parasite is an organism that lives on or in a host organism and gets its food from or at the expense of its host. Parasites of humans include protozoans, helminths, and ecto-parasites (organisms that live on the external surface of a host). They are responsible for many diseases and are transmitted to their hosts most often through the ingestion of contaminated food, water or through the bite of an arthropod (e.g., a fly or tick), which can act as an intermediate host and as a vector. Parasitic diseases of humans are a major global health problem causing significant morbidity and mortality, especially in developing countries. Each year there are hundreds of millions of people infected with disease-causing parasites, particularly in tropical and subtropical regions of the world, resulting in an estimated one million deaths. Therefore, there is a dire need of novel anti-parasitic drugs.

MCE has a unique collection of 637 compounds with validated anti-parasitic activity which offer researchers an opportunity to screen novel anti-parasitic targets.

HY-L007

Immunology/Inflammation Compound Library

7,742 compounds

The immune system is a host defense system comprising many biological structures and processes within an organism that protects against disease. To function properly, an immune system must detect a wide variety of agents, known as pathogens, from viruses to parasitic worms, and distinguish them from the organism's own healthy tissue. Inflammation is also the body's attempt at self-protection to remove harmful stimuli and begin the healing process. It’s part of the body's immune response. The immune system recognizes damaged cells, irritants, and pathogens, and inflammation begins the healing process. Inflammatory abnormalities are a large group of disorders that underlie a vast variety of human diseases. The immune system is often involved with inflammatory disorders, demonstrated in both allergic reactions and some myopathies, with many immune system disorders resulting in abnormal inflammation.

MCE designs a unique collection of 7,742 compounds that are useful tool for Immunology/Inflammation research or autoimmune inflammatory diseases drug discovery.

Cat. No.	Product Name	Type

HY-B0497G

Niclosamide

BAY2353

Fluorescent Dye

Niclosamide (GMP) is Niclosamide (HY-B0497) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Niclosamide (BAY2353) is an orally active antihelminthic agent used in parasitic infection research . Niclosamide is a STAT3 inhibitor with an IC₅₀ of 0.25 μM in HeLa cells . Niclosamide has biological activities against cancer, inhibits DNA replication in Vero E6 cells .

Cat. No.	Product Name	Type

HY-129038

GR24 1 Publications Verification Strigolactone GR24	Biochemical Assay Reagents
(Rac)-GR24 (Strigolactone GR24) is a plant hormone analog. (Rac)-GR24 can mimic the natural germination stimulus of parasitic plant seeds, promoting seed germination in the absence of host plants, thereby reducing the number of parasitic seeds in the soil. (Rac)-GR24 can be used in agricultural research .

HY-W011517

2-Fluoroadenosine 2FA	Biochemical Assay Reagents
2-Fluoroadenosine (2FA) is a nucleoside analogue. 2-Fluoroadenosine has antiparasite activity with EC₅₀ value of 0.842 mM for Cryptosporidium parvum. 2-Fluoroadenosine has a highly specific structural basis for MtADK. 2-Fluoroadenosine is commonly used in the study of parasitic conditions .

HY-W011517R

2-Fluoroadenosine (Standard) 2FA (Standard)	Biochemical Assay Reagents
2-Fluoroadenosine (2FA) is a nucleoside analogue. 2-Fluoroadenosine has antiparasite activity with EC₅₀ value of 0.842 mM for Cryptosporidium parvum. 2-Fluoroadenosine has a highly specific structural basis for MtADK. 2-Fluoroadenosine is commonly used in the study of parasitic conditions .

HY-B0497G

Niclosamide

BAY2353

Biochemical Assay Reagents

Cat. No.	Product Name	Target	Research Area

HY-P11155

Halictine 2	Parasite	Infection
Halictine 2 is an antimicrobial peptide. Halictine 2 exhibits promising anti-parasitic activity against Leishmania spp., targeting both the extracellular infective metacyclic promastigotes and intracellular amastigotes. Halictine 2 can be used for the study of leishmaniases .

Cat. No.	Product Name	Target	Research Area	Image

HY-P990208

Anti-Mouse IL-9 Antibody (9C1)	Interleukin Related NF-κB Parasite	Infection Inflammation/Immunology Cancer
Anti-Mouse IL-9 Antibody (9C1) is an anti-mouse IL-9 IgG2a monoclonal antibody. Anti-Mouse IL-9 Antibody (9C1) can reduce the activation of NF-κB signaling pathway and decrease the infiltration of inflammatory cells. Anti-Mouse IL-9 Antibody (9C1) effectively reduces Th9 cell-mediated allergic reactions and anti-tumor effects. Anti-Mouse IL-9 Antibody (9C1) can be used for researches on inflammation, infection conditions and cancer such as parasitic infections, allergic reactions, breast cancer and osteosarcoma .

HY-P990201

Anti-Mouse L-Selectin/CD62L Antibody (Mel-14)	L-Selectin	Infection Metabolic Disease Inflammation/Immunology
Anti-Mouse L-Selectin/CD62L Antibody (Mel-14) is an anti-mouse L-Selectin/CD62L IgG2a monoclonal antibody. Anti-Mouse L-Selectin/CD62L Antibody (Mel-14) can significantly inhibit the migration of T cells and B cells. Anti-Mouse L-Selectin/CD62L Antibody (Mel-14) can block initial lymphocyte homing. Anti-Mouse L-Selectin/CD62L Antibody (Mel-14) can be used for researches on inflammation, metabolic and infection conditions such as diabetes and parasitic infections .

HY-P990214

Anti-Mouse IL-3 Antibody (MP2-8F8)	Interleukin Related Parasite	Infection Inflammation/Immunology
Anti-Mouse IL-3 Antibody (MP2-8F8) is an anti-mouse IL-3 IgG1 monoclonal antibody. Anti-Mouse IL-3 Antibody (MP2-8F8) relieves joint inflammation by reducing synovial leukocyte infiltration and cytokine levels. Anti-Mouse IL-3 Antibody (MP2-8F8) can reduce the accumulation of basophils. Anti-Mouse IL-3 Antibody (MP2-8F8) can be used for researches on inflammation or infection conditions such as arthritis and parasitic infections .

HY-P990801

Anti-Mouse CD11a/LFA-1α Antibody (M17/4)	Integrin Parasite Bacterial	Infection Neurological Disease Inflammation/Immunology Cancer
Anti-Mouse CD11a/LFA-1α Antibody (M17/4) is an anti-mouse CD11a/LFA-1α IgG2a monoclonal antibody. Anti-Mouse CD11a/LFA-1α Antibody (M17/4) can reduce the recruitment of effector memory CD8 T cells. Anti-Mouse CD11a/LFA-1α Antibody (M17/4) promotes the formation of xenograft tumors by reducing immune rejection reactions. Anti-Mouse CD11a/LFA-1α Antibody (M17/4) can be used for researches on cancer, infection conditions and immunology such as glioblastoma, parasitic and bacterial infections. The recommend isotype control of Anti-Mouse CD11a/LFA-1α Antibody (M17/4): Rat IgG2a kappa, Isotype Control (HY-P990679) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0150

Monensin sodium Maximum Cited Publications 38 Publications Verification Monensin A sodium	Structural Classification Microorganisms Classification of Application Fields Antibiotics Antibacterial Disease Research Disease Research Fields Other Antibiotics Plant agriculture research Source Classification Cancer	Exosomes Bacterial Antibiotic Na+/H+ Exchanger (NHE) Parasite Apoptosis Fungal Wnt
Monensin (Monensin A) sodium, an orally active antibiotic, is an ionophore that mediates Na ⁺/H ⁺ exchange. Monensin sodium is a potent Wnt signaling inhibitor. Monensin sodium causes a marked enlargement of the multivesicular bodies (MVBs) and regulates exosome secretion. Monensin sodium can be used for bacterial, fungal, and parasitic infections research, and shows anticancer effects .

HY-B0956

Paromomycin sulfate 4 Publications Verification Aminosidine sulfate	Classification of Application Fields Anti-parasitic Antibacterial Disease Research Other Antibiotics Infection Plant Cell Culture Microorganisms Antibiotics Resistance Selection Mammalian Cell Culture Disease Research Fields Source Classification	Antibiotic Parasite Bacterial
Paromomycin (Aminosidine) sulfate, a neomycin (HY-B0470) derivative, is a broad spectrum aminoglycoside antibiotic with amebicidal and bactericidal effects. Paromomycin sulfate prematures termination of translation of mRNA and inhibits protein synthesis by specifically binds to the RNA oligonucleotide at the A site of bacterial 30S ribosomes. Paromomycin sulfate can be used for the research of bacterial and parasitic infections .

HY-N2364

Arecoline 5 Publications Verification	Structural Classification Neurological Disease Classification of Application Fields Areca catechu L. Metabolic Disease Plants Infection Alkaloids Piperidine Alkaloids Palmae Inflammation/Immunology Disease Research Fields Source Classification	mAChR nAChR
Arecoline, a naturally brain-penetrant and orally active occurring psychoactive alkaloid, is a partial agonist of nicotinic and muscarinic acetylcholine receptor. Arecoline exhibits stimulation, alertness, anxiolysis and anti-parasitic effects. Arecoline also can induce oxidative stress .

HY-50730

Asparagusic acid 4 Publications Verification	Infection Liliaceae Classification of Application Fields Ketones, Aldehydes, Acids Plants Disease Research Fields Source Classification Asparagus officinalis L.	Parasite Endogenous Metabolite
Asparagusic acid is a sulfur-containing flavor component produced by Asparagus officinalis Linn., with anti-parasitic effect. Asparagusic acid is a plant growth inhibitor .

HY-B0489

Arecoline hydrobromide 5 Publications Verification methyl 1,2,5,6-tetrahydro-1-methyl-3-pyridinecarboxylate hydrobromide	Structural Classification Neurological Disease Classification of Application Fields Areca catechu L. Metabolic Disease Plants Infection Alkaloids Other Alkaloids Palmae Inflammation/Immunology Disease Research Fields Source Classification	mAChR nAChR
Arecoline hydrobromide, a naturally brain-penetrant and orally active occurring psychoactive alkaloid, is a partial agonist of nicotinic and muscarinic acetylcholine receptor. Arecoline hydrobromide exhibits stimulation, alertness, anxiolysis and anti-parasitic effects. Arecoline hydrobromide also can induce oxidative stress .

HY-W071746

Linolelaidic acid 1 Publications Verification Linoelaidic acid	Cardiovascular Disease Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite Parasite Apoptosis
Linolelaidic acid (Linoelaidic acid) is an omega-6 trans fatty acid (TFA) that is an essential nutrient with oral activity. Linolelaidic acid can be added to enteral nutrition (oral), parenteral nutrition (intravenous), and infant formula. Linolelaidic acid has anti-inflammatory and anti-parasitic ((Parasite)) activities, and can induce Apoptosis. Linolelaidic acid is useful for research in infections .

HY-15311

Avermectin B1 5 Publications Verification Abamectin; Avermectin B1a-Avermectin B1b mixt.	Structural Classification Classification of Application Fields Anti-parasitic Antibacterial Disease Research Biological Pesticide Research Agricultural Research Infection Microorganisms Macrolide Antibiotics Antibiotics Animal Husbandry Inflammation/Immunology Disease Research Fields Source Classification	Environmental Pollutants Antibiotic Autophagy Parasite Apoptosis Reactive Oxygen Species (ROS)
Avermectin B1 (Abamectin) is a mixture of two similar segments of avermectin. Avermectin B1 is an orally anti-infection agent, which can be used in the research of parasitic worms, insect pests, agriculture and animal husbandry. Avermectin B1 can also induce the production of ROS and induces cytotoxicity, apoptosis and autophagy .

HY-121054

Chalcone 1 Publications Verification (E/Z)-Benzylideneacetophenone	Structural Classification Chalcones Flavonoids Classification of Application Fields Leguminosae Plants Endogenous metabolite Glycyrrhiza uralensis Fisch. Inflammation/Immunology Disease Research Fields Source Classification	Bacterial Parasite
Chalcone is isolated from Glycyrrhiza uralensis and used to synthesize chalcone derivatives. Chalcone derivatives possess varied biological and pharmacological activity, including anti-inflammatory, antioxidative, antibacterial, anticancer, and anti-parasitic activities .

HY-W016586

Acivicin 2 Publications Verification AT-125; U-42126	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Disease Research Fields Source Classification	Parasite γ-Glutamyl Transferase (GGT)
Acivicin (AT-125), a natural product produced by Streptomyces sviceus is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin can across the blood-brain barrier and has anti-cancer, anti-parasitic properties .

HY-W016586A

Acivicin hydrochloride 2 Publications Verification AT-125 hydrochloride; U-42126 hydrochloride	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Disease Research Fields Source Classification	Parasite
Acivicin hydrochloride (AT-125 hydrochloride), a natural product produced by Streptomyces sviceus, is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin hydrochloride can across the blood-brain barrier and has anti-cancer, anti-parasitic properties .

HY-N4302

Monensin Maximum Cited Publications 38 Publications Verification Monensin A	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Disease Research Fields Source Classification	Exosomes Bacterial Apoptosis Antibiotic Parasite Na+/H+ Exchanger (NHE) Fungal Wnt
Monensin (Monensin A), an orally active antibiotic, is an ionophore that mediates Na ⁺/H ⁺ exchange. Monensin is a potent Wnt signaling inhibitor. Monensin causes a marked enlargement of the multivesicular bodies (MVBs) and regulates exosome secretion. Monensin can be used for bacterial, fungal, and parasitic infections research, and shows anticancer effects .

HY-N1944

Nerolidol,98%(isomers mixture) 2 Publications Verification	Infection Structural Classification other families Classification of Application Fields Terpenoids Sesquiterpenes Plants Endogenous metabolite Disease Research Fields Source Classification	Environmental Pollutants Bacterial Endogenous Metabolite Fungal Parasite
Nerolidol has multiple natural membrane activities, possesses anti-cancer, anti-inflammatory, antibacterial and anti-insect activity. Nerolidol Suppresses parasitic activity, suppresses bloodsucking diseases, bloodworm diseases, and other diseases. Nerolidol can protect the cells from lipid and protein properties, damage to DNA, and protect the cells from damage .

HY-N0078

Ginkgolic Acid (C13:0) Ginkgolic acid (13:0); Ginkgoneolic Acid; 6-Tridecylsalicylic acid	Infection Monophenols Ginkgoaceae Classification of Application Fields Ketones, Aldehydes, Acids Phenols Plants Ginkgo biloba Disease Research Fields Source Classification	Bacterial PI3K Parasite
Ginkgolic Acid (C13:0) (Ginkgoneolic Acid) is an anti-cariogenic agent and a PI3Kδ inhibitor (IC₅₀: 2.49 μM). Ginkgolic Acid (C13:0) exhibits antibacterial and anti-parasitic activities. Ginkgolic Acid (C13:0) can also inhibit mast cell degranulation (IC₅₀: 2.40 μM) .

HY-W012657

4-Ethylbenzaldehyde	Structural Classification Classification of Application Fields Leguminosae Glycine max (L.) merr Ketones, Aldehydes, Acids Metabolic Disease Plants Endogenous metabolite Disease Research Fields Source Classification	Environmental Pollutants Parasite
4-Ethylbenzaldehyde is an aldehyde type organic compound with an almond-like odor. 4-Ethylbenzaldehyde is naturally present in various foods such as grilled meat, black tea, peanuts, etc. 4-Ethylbenzaldehyde has significant effects in controlling plant parasitic nematodes. 4-Ethylbenzaldehyde has genotoxicity and potential for liver damage in zebrafish models .

HY-N10534

Lewis X trisaccharide Lewis X	Infection Structural Classification Polysaccharides Animals Classification of Application Fields Inflammation/Immunology Disease Research Fields Saccharides Cancer	Parasite
Lewis X trisaccharide (Lewis X, Le ^x) is a potent T_H2 regulator, antagonizes LPS-induced IL-12 immune expression. Lewis X trisaccharide is a human histo-blood group antigen, plays an key role in cell-cell adhesion, and servers as a tumor marker. Lewis X trisaccharide is highly expressed in the outer membrane of the parasite, can be used for the immunology research of schistosomiasis .

HY-N15133

Solanacol (-)-Solanacol	Structural Classification Natural Products Solanum lycopersicum L. Solanaceae Plants Source Classification	Drug Derivative
Solanacol ((-)-Solanacol) is a strigolactone germination stimulant that can be isolated from tobacco (Nicotiana tabacum L.). Solanacol stimulates the germination of root parasitic weed seeds .

HY-N0150R

Monensin sodium (Standard) Monensin A sodium (Standard)	Structural Classification Microorganisms Antibiotics Antibacterial Disease Research Other Antibiotics Plant agriculture research Source Classification	Reference Standards Exosomes Bacterial Antibiotic Na+/H+ Exchanger (NHE) Parasite Apoptosis Fungal Wnt
Monensin (sodium) (Standard) is the analytical standard of Monensin (sodium). This product is intended for research and analytical applications. Monensin (Monensin A) sodium, an orally active antibiotic, is an ionophore that mediates Na+/H+ exchange. Monensin sodium is a potent Wnt signaling inhibitor. Monensin sodium causes a marked enlargement of the multivesicular bodies (MVBs) and regulates exosome secretion. Monensin sodium can be used for bacterial, fungal, and parasitic infections research, and shows anticancer effects .

HY-N1944R

Nerolidol (Standard)	Structural Classification Microorganisms other families Terpenoids Sesquiterpenes Plants Endogenous metabolite Source Classification	Reference Standards Bacterial Fungal Parasite Endogenous Metabolite
Nerolidol (Standard) is the analytical standard of Nerolidol. This product is intended for research and analytical applications. Nerolidol has multiple natural membrane activities, possesses anti-cancer, anti-inflammatory, antibacterial and anti-insect activity. Nerolidol Suppresses parasitic activity, suppresses bloodsucking diseases, bloodworm diseases, and other diseases. Nerolidol can protect the cells from lipid and protein properties, damage to DNA, and protect the cells from damage .

HY-N0924A

(±)-Stylopine hydrochloride 1 Publications Verification Tetrahydrocoptisine hydrochloride	Alkaloids Classification of Application Fields Flacourtia indica Flacourtiaceae Plants Isoquinoline Alkaloids Inflammation/Immunology Disease Research Fields Source Classification	Parasite
(±)-Stylopine (Tetrahydrocoptisine) hydrochloride is an alkaloid compound originally isolated from Corydalis tubers that exhibits anti-inflammatory and anti-parasitic activities .

HY-N7448

5-Deoxystrigol	Structural Classification Natural Products Orobanche crenata Forssk. Classification of Application Fields Other Diseases Orobanchaceae Plants Phytohormone Disease Research Fields Source Classification Agricultural Research	Others
5-Deoxystrigol is a strigolactone found in Fabaceae plants. 5-Deoxystrigol can stimulate seed germination .

HY-N15748

Pelorol (-)-Pelorol	Terpenoids Sesquiterpenes Marine natural products Sponge Source Classification	Parasite
Pelorol ((-)-Pelorol) is a sesquiterpene found in the tropical marine sponge Dactylospongia elegans. Pelorol has weak antitrypanosomal activity with an IC₅₀ of 17.4 μg/mL and antiplasmodial activity against Plasmodium falciparum clones K1 and NF54 with IC₅₀ values of 786 ng/mL and 1911 ng/mL, respectively. Pelorol is promising for research of parasitic diseases, such as trypanosomiasis and malaria .

HY-N12177

Cryptosporioptide A	Flavonoids Microorganisms Other Flavonoids Source Classification	Phosphatase SHP1
Cryptosporioptide A (Compound 3) is a pigment protein tyrosine phosphatase inhibitor derived from the insect-parasitic fungus Cordyceps gracilioides. Cryptosporioptide A inhibits PTP1B, SHP2, CDC25B, LAR and SHP1 enzymes with IC₅₀ of 7.3, 5.7, 7.6, >50, 4.9 μg/mL, respectively .

HY-W071746R

Linolelaidic acid (Standard) Linoelaidic acid (Standard)	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite Parasite Apoptosis
Linolelaidic acid (Standard) is the analytical standard of Linolelaidic acid. This product is intended for research and analytical applications. Linolelaidic acid (Linoelaidic acid) is an omega-6 trans fatty acid (TFA) that is an essential nutrient with oral activity. Linolelaidic acid can be added to enteral nutrition (oral), parenteral nutrition (intravenous), and infant formula. Linolelaidic acid has anti-inflammatory and anti-parasitic ((Parasite)) activities, and can induce Apoptosis. Linolelaidic acid is useful for research in infections[1][2][3].

HY-50730R

Asparagusic acid (Standard)	Structural Classification Liliaceae Ketones, Aldehydes, Acids Plants Source Classification Asparagus officinalis L.	Parasite Endogenous Metabolite Reference Standards
Asparagusic acid (Standard) is the analytical standard of Asparagusic acid. This product is intended for research and analytical applications. Asparagusic acid is a sulfur-containing flavor component produced by Asparagus officinalis Linn., with anti-parasitic effect. Asparagusic acid is a plant growth inhibitor .

HY-B0489R

Arecoline hydrobromide (Standard) methyl 1,2,5,6-tetrahydro-1-methyl-3-pyridinecarboxylate hydrobromide (Standard)	Alkaloids Structural Classification Areca catechu L. Other Alkaloids Palmae Plants Source Classification	Reference Standards mAChR nAChR
Arecoline hydrobromide (Standard) is the analytical standard of Arecoline hydrobromide. This product is intended for research and analytical applications. Arecoline hydrobromide, a naturally brain-penetrant and orally active occurring psychoactive alkaloid, is a partial agonist of nicotinic and muscarinic acetylcholine receptor. Arecoline hydrobromide exhibits stimulation, alertness, anxiolysis and anti-parasitic effects. Arecoline hydrobromide also can induce oxidative stress .

HY-N16123

Chloranthalactone C	Terpenoids Sesquiterpenes Chloranthaceae Plants Chloranthus fortunei (A. Gray) Solms-Laub Source Classification	Parasite
Chloranthalactone C (Compound 43), a lindenane-type sesquiterpenoid, is an antimalarial agent. Chloranthalactone C can be isolated from plant Chloranthus japonicas Sieb. Chloranthalactone C inhibits Chloroquine (HY-17589A)-resistant Plasmodium falciparum strain Dd2 growth. Chloranthalactone C can be used for parasitic infections research .

HY-15311R

Avermectin B1 (Standard) Abamectin (Standard); Avermectin B1a-Avermectin B1b mixt. (Standard)	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Animal Husbandry Anti-parasitic Antibacterial Disease Research Source Classification	Reference Standards Parasite Autophagy Apoptosis Reactive Oxygen Species (ROS) Antibiotic
Avermectin B1 (Standard) is the analytical standard of Avermectin B1. This product is intended for research and analytical applications. Avermectin B1 (Abamectin) is a mixture of two similar segments of avermectin. Avermectin B1 is an orally anti-infection agent, which can be used in the research of parasitic worms, insect pests, agriculture and animal husbandry. Avermectin B1 can also induce the production of ROS and induces cytotoxicity, apoptosis and autophagy .

HY-B0489A

Arecoline hydrochloride	Structural Classification Neurological Disease Classification of Application Fields Areca catechu L. Metabolic Disease Plants Infection Alkaloids Other Alkaloids Palmae Inflammation/Immunology Disease Research Fields Source Classification	mAChR nAChR
Arecoline hydrochloride, a naturally brain-penetrant and orally active occurring psychoactive alkaloid, is a partial agonist of nicotinic and muscarinic acetylcholine receptor. Arecoline hydrochloride exhibits stimulation, alertness, anxiolysis and anti-parasitic effects. Arecoline hydrochloride also can induce oxidative stress .

HY-B0956R

Paromomycin sulfate (Standard) Aminosidine sulfate (Standard)	Structural Classification Plant Cell Culture Microorganisms Antibiotics Resistance Selection Mammalian Cell Culture Anti-parasitic Antibacterial Disease Research Other Antibiotics Source Classification	Reference Standards Antibiotic Parasite Bacterial
Paromomycin (sulfate) (Standard) is the analytical standard of Paromomycin (sulfate). This product is intended for research and analytical applications. Paromomycin (Aminosidine) sulfate, a neomycin (HY-B0470) derivative, is a broad spectrum aminoglycoside antibiotic with amebicidal and bactericidal effects. Paromomycin sulfate prematures termination of translation of mRNA and inhibits protein synthesis?by specifically binds to the RNA oligonucleotide at the A site of bacterial 30S ribosomes. Paromomycin sulfate can be used for the research of bacterial and parasitic infections .

HY-N15872

Fluoro azasterol	Lipid	Fluorescent Dye
Fluoro azasterol is a class of azasterols. Azasterols are a group of compounds that have uses as anti-parasitic, antifungal, and anti-toxoplasma agents.

HY-N0924R

(±)-Stylopine (Standard) Tetrahydrocoptisine (Standard)	Alkaloids Structural Classification Chelidonium majus Plants Isoquinoline Alkaloids Papaveraceae Source Classification	Parasite Reference Standards
(±)-Stylopine (Tetrahydrocoptisine) is an alkaloid compound originally isolated from Corydalis tubers that exhibits anti-inflammatory and anti-parasitic activities .

HY-N2708

6-epi-8-O-Acetylharpagide	Strobocalyx arborea (Buch.-Ham.) Sch. Bip. Iridoids Terpenoids Labiatae Plants Source Classification	Others
6-Epi-8-O-acetylharpagide is a derivative of the anti-parasitic and anti-inflammatory compound Harpagide (HY-N0397) .

HY-N8846

dl-Aloesol	Flavonoids Microorganisms Other Flavonoids Source Classification	Fungal
dl-Aloesol is a natural product that can be isolated from fungus Aspergillus sp. Aspergillus sp metabolites has cytotoxic, antibacterial, free radical scavenging, anti-parasitic, antiviral and antiproliferative activities, etc .

HY-121054R

Chalcone (Standard) (E/Z)-Benzylideneacetophenone (Standard)	Structural Classification Chalcones Flavonoids Leguminosae Plants Endogenous metabolite Glycyrrhiza uralensis Fisch. Source Classification	Bacterial Parasite Reference Standards
Chalcone (Standard) is the analytical standard of Chalcone. This product is intended for research and analytical applications. Chalcone is isolated from Glycyrrhiza uralensis and used to synthesize chalcone derivatives. Chalcone derivatives possess varied biological and pharmacological activity, including anti-inflammatory, antioxidative, antibacterial, anticancer, and anti-parasitic activities .

HY-N16426

Mycoleptone A	Natural Products Microorganisms Source Classification	Parasite
Mycoleptone A is an azafluorenone compound. Mycoleptone A exhibits certain anti-leishmanial activity, with an LD₅₀ of 28.5 μM against L. major. Mycoleptone A shows cytotoxicity against human prostate cancer cell line PC3, with an IC₅₀ of 10.0 μM. Mycoleptone A can be used in research on anti-parasitic and anti-tumor aspects .

HY-W016586AR

Acivicin hydrochloride (Standard) AT-125 hydrochloride (Standard); U-42126 hydrochloride (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source Classification	Reference Standards Parasite γ-Glutamyl Transferase (GGT)
Acivicin (hydrochloride) (Standard) is the analytical standard of Acivicin (hydrochloride). This product is intended for research and analytical applications. Acivicin hydrochloride (AT-125 hydrochloride), a natural product produced by Streptomyces sviceus, is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin hydrochloride can across the blood-brain barrier and has anti-cancer, anti-parasitic properties[1][2].

HY-N7236

Pervicoside B	Triterpenes Animals Terpenoids Source Classification	Parasite Fungal
Pervicoside B is a glycoside C isolated from Neothyone gibbosa sea cucumber. In vitro studies have shown that Pervicoside B has a potent antiparasitic effect against Leishmania mexicana, inhibiting 100% of promastigotes at 5-10 μg/mL. Pervicoside B also exhibits strong antifungal activity against Aspergillus niger, with MIC values ranging from 4.65 to 16.7 μg/mL. Pervicoside B has potential applications in the inhibition of parasitic infections and fungal diseases .

HY-N0677AR

Kalii Dehydrographolidi Succinas (Standard) Potassium dehydroandrographolide succinate (Standard)	Structural Classification Acanthaceae Simsia foetida (Cav.) S.F.Blake Terpenoids Diterpenoids Plants Source Classification	Antibiotic Reference Standards
Paromomycin (sulfate) (Standard) is the analytical standard of Paromomycin (sulfate). This product is intended for research and analytical applications. Paromomycin (Aminosidine) sulfate, a neomycin (HY-B0470) derivative, is a broad spectrum aminoglycoside antibiotic with amebicidal and bactericidal effects. Paromomycin sulfate prematures termination of translation of mRNA and inhibits protein synthesis?by specifically binds to the RNA oligonucleotide at the A site of bacterial 30S ribosomes. Paromomycin sulfate can be used for the research of bacterial and parasitic infections .

HY-W012657R

4-Ethylbenzaldehyde (Standard)	Structural Classification Leguminosae Glycine max (L.) merr Ketones, Aldehydes, Acids Plants Endogenous metabolite Source Classification	Reference Standards Parasite
4-Ethylbenzaldehyde (Standard) is the analytical standard of 4-Ethylbenzaldehyde (HY-W012657). This product is intended for research and analytical applications. 4-Ethylbenzaldehyde is an aldehyde type organic compound with an almond-like odor. 4-Ethylbenzaldehyde is naturally present in various foods such as grilled meat, black tea, peanuts, etc. 4-Ethylbenzaldehyde has significant effects in controlling plant parasitic nematodes. 4-Ethylbenzaldehyde has genotoxicity and potential for liver damage in zebrafish models.

HY-N0078R

Ginkgolic Acid (C13:0) (Standard) Ginkgolic acid (13:0) (Standard); Ginkgoneolic Acid (Standard); 6-Tridecylsalicylic acid (Standard)	Structural Classification Monophenols Ginkgoaceae Ketones, Aldehydes, Acids Phenols Plants Ginkgo biloba Source Classification	Reference Standards Bacterial PI3K Parasite
Ginkgolic Acid (C13:0) (Standard) is the analytical standard of Ginkgolic Acid (C13:0) (HY-N0078). This product is intended for research and analytical applications. Ginkgolic Acid (C13:0) (Ginkgoneolic Acid) is an anti-cariogenic agent and a PI3Kδ inhibitor (IC₅₀: 2.49 μM). Ginkgolic Acid (C13:0) exhibits antibacterial and anti-parasitic activities. Ginkgolic Acid (C13:0) can also inhibit mast cell degranulation (IC₅₀: 2.40 μM) .

HY-126638

Marcfortine A NSC 324645	Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Source Classification	Parasite
Marcfortine A is an indole alkaloid originally isolated from P. roqueforti. It has nematocidal activity against the parasitic nematode H. contortus (LD99=0.06 μg/mL) and inhibits motility of adult worms (EC₅₀=2 μM). Marcfortine A eliminates H. contortus, T. colubriformis, and O. ostertagi from experimentally infected jirds (ED95s=0.33, 0.11, and 2.5 mg/animal, respectively). It dose-dependently inhibits nicotine-induced calcium mobilization in SH-SY5Y and TE-671 cells expressing α3 subunit-containing human nicotinic acetylcholine receptors (nAChRs) and muscle-type nAChRs, respectively.

HY-W142497

3-Methyl-2(5H)-furanone	Structural Classification Natural Products Nicotiana tabacum L. Solanaceae Plants Source Classification	Drug Intermediate
3-Methyl-2(5H)-furanone is the common structural unit in natural and several synthetic strigolactones, which are germination stimulants for seeds of the parasitic weeds Striga and Orobanche spp. .

HY-N18822

Wormseed oil	Structural Classification Extract	Others
Wormseed oil is derived from the wormseed plant and is widely recognized for its anthelmintic properties, making it highly effective in studying various parasitic infections.

HY-136897

Avermectin A2b	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Source Classification	Endogenous Metabolite Insecticide Parasite
Avermectin A2b (Compound A2b) is an avermectin. Avermectins are produced during the fermentation of the actinomycete Streptomyces avermitilis. Avermectins possess anthelmintic and insecticidal properties, and are commonly used as insecticides for the control of pests and parasitic worms .

HY-W783593

Avermectin A1a	Structural Classification Microorganisms Antibiotics Source Classification	Parasite
Avermectin A1a is a potent and broad-spectrum antiparasitic agent. Avermectin A1a targets nematodes and arthropods by binding to their glutamate-gated chloride channels to block nerve signal transmission and induce paralysis. Avermectin A1a can be used for the study of parasitic infection .

HY-W707148

4-Methyltridecane	Structural Classification Natural Products Rutaceae Plants Skimmia reevesiana Fort. Source Classification	Endogenous Metabolite
4-Methyltridecane is a volatile substance specifically released by cabbage root flies (Delia radicum) after feeding. 4-Methyltridecane might be a key signal for the parasitoid bee Trybliographa rapae (Delia radicum’s specific parasitic predator) to locate the host. 4-Methyltridecane can serve as a specific marker for root damage in turnips (Brassica rapa subsp. Rapa) .

HY-W102349

S-Methyl thioacetate	Structural Classification Natural Products Morinda citrifolia Linn. Rubiaceae Plants Source Classification	Parasite
S-Methyl thioacetate is a toxicant with fumigant activity, can be found in emissions from Bacillus oshimensis, Burkholderia gladioli, Burkholderia cepacia, and Pseudomonas oryzihabitans. S-Methyl thioacetate exerts fumigant toxicity against Caenorhabditis elegans and root-knot nematode Meloidogyne incognita. S-Methyl thioacetate functions as a bacterial volatile organic compound. S-Methyl thioacetate can be used for the research of plant-parasitic nematode infection .

Cat. No.	Product Name	Chemical Structure

HY-B0357S

Diclazuril-d4
Diclazuril-d₄ is deuterium labeled Diclazuril. Diclazuril (R-64433), a benzeneacetonitrile derivative, is a potent and orally active anticoccidial agent. Diclazuril can be used for the research of certain infectious and parasitic diseases, including coccidiosis, acute toxoplasmosis, equine protozoal pyoencephalitis (EPM) et.al .

HY-123305S

5-Hydroxymebendazole-d3
5-Hydroxymebendazole-d₃ is a deuterium labeled 5-Hydroxymebendazole. 5-Hydroxymebendazole is the one metabolite of Benzimidazoles .

HY-17596S

Closantel-13C6
Closantel- ¹³C₆ is the ¹³C₆ labeled Closantel. Closantel is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC50 of 1.6 μM and a Ki of 468 nM. Closantel inhibits the O. volvulus L3 to L4 molt of developing.

HY-B0497S2

Niclosamide-d3
Niclosamide-d₃ (BAY2353-d₃) is deuterium labeled Niclosamide. Niclosamide (BAY2353) is an orally active antihelminthic agent used in parasitic infection research . Niclosamide is a STAT3 inhibitor with an IC₅₀ of 0.25 μM in HeLa cells . Niclosamide has biological activities against cancer, inhibits DNA replication in Vero E6 cells .

HY-B0945S

Nitromide-13C6
Nitromide- ¹³C₆ (3,5-Dinitrobenzamide- ¹³C₆) is the ¹³C-labeled Nitromide (HY-B0945). Nitromide is an anti-parasitic agent .

HY-12651S

Primaquine-d3 diphosphate
Primaquine-d₃ (diphosphate) is the deuterium labeled Primaquine diphosphate. Primaquine Diphosphate (Primaquine phosphate), an 8-aminoquinoline, exerts a broad spectrum of activities against various stages of parasitic malaria. Primaquine Diphosphate remains as the only agent that destroys late hepatic stages and latent tissue forms of Plasmodium vivax and Plasmodium ovale .

HY-W654156

Diclazuril-13C3,15N2
Diclazuril- ¹³C₃, ¹⁵N ² is ¹³C and ¹⁵N labeled Diclazuril. Diclazuril (R-64433), a benzeneacetonitrile derivative, is a potent and orally active anticoccidial agent. Diclazuril can be used for the research of certain infectious and parasitic diseases, including coccidiosis, acute toxoplasmosis, equine protozoal pyoencephalitis (EPM) et.al .

HY-B0497BS

Niclosamide-13C6 monohydrate

Niclosamide- ¹³C₆ (monohydrate) is the ¹³C labeled Niclosamide monohydrate . Niclosamide (BAY2353) monohydrate is an orally active antihelminthic agent used in parasitic infection research . Niclosamide monohydrate is a STAT3 inhibitor with an IC₅₀ of 0.25 μM in HeLa cells . Niclosamide monohydrate has biological activities against cancer, and inhibits DNA replication in Vero E6 cells .

HY-N1944S

Nerolidol-d4

Nerolidol-d₄ is deuterated labeled Nerolidol (HY-N1944). Nerolidol has multiple natural membrane activities, possesses anti-cancer, anti-inflammatory, antibacterial and anti-insect activity. Nerolidol Suppresses parasitic activity, suppresses bloodsucking diseases, bloodworm diseases, and other diseases. Nerolidol can protect the cells from lipid and protein properties, damage to DNA, and protect the cells from damage .

HY-W739837

Arecoline-d5 hydrobromide
Arecoline-d₅ hydrobromide is the deuterium labeled Arecoline hydrobromide (HY-B0489). Arecoline hydrobromide, a naturally occurring psychoactive alkaloid, is a partial agonist of nicotinic and muscarinic acetylcholine receptor. Arecoline hydrobromide exhibits stimulation, alertness, anxiolysis and anti-parasitic effects. Arecoline hydrobromide also can induce oxidative stress .

Cat. No.	Product Name		Classification

HY-174604

Human IL4 mRNA		mRNA Interleukin & Receptors
Human IL4 mRNA encodes the human interleukin 4 (IL4) protein, a pleiotropic cytokine produced by activated T cells. IL4 is considered an important cytokine for tissue repair, counterbalancing the effects of proinflammatory type 1 cytokines, however, it also promotes allergic airway inflammation. Moreover, IL-4 mediates and regulates a variety of human host responses such as allergic, anti-parasitic, wound healing, and acute inflammation.

HY-174771

Human CCL11 mRNA		mRNA Chemokine & Receptors
Human CCL11 mRNA encodes the human C-C motif chemokine ligand 11 (CCL11) protein, a member of the CC subfamily. CCL11 is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections.

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0497G

Niclosamide BAY2353	Antibiotic Parasite STAT	Cancer
Niclosamide (GMP) is Niclosamide (HY-B0497) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Niclosamide (BAY2353) is an orally active antihelminthic agent used in parasitic infection research . Niclosamide is a STAT3 inhibitor with an IC₅₀ of 0.25 μM in HeLa cells . Niclosamide has biological activities against cancer, inhibits DNA replication in Vero E6 cells .

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MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
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parasitic

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Screening Libraries

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