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radical

" in MedChemExpress (MCE) Product Catalog:

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Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

373

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Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W015913

Pyruvic acid sodium 15+ Cited Publications Sodium 2-oxopropanoate; Acetylformic acid sodium	Reactive Oxygen Species (ROS) Endogenous Metabolite	Metabolic Disease
Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS .

HY-N0499

Cyanidin Chloride 4 Publications Verification IdB 1027	Prostaglandin Receptor	Inflammation/Immunology
Cyanidin Chloride (IdB 1027) is an orally active antioxidant and enzyme inhibitor. Cyanidin Chloride has IC₅₀ values of 90 μM and 60 μM against PGHS-1 and PGHS-2, respectively. Cyanidin Chloride exhibits excellent antioxidant and anti-inflammatory activities, scavenges free radicals, inhibits lipid peroxidation, and protects DNA from cleavage. Cyanidin Chloride can be used in the research of inflammatory diseases .

HY-141898

Biotin-4-aminophenol	Fluorescent Dye	Others
Biotin-4-aminophenol is a biotin-phenol analog. Biotin-4-aminophenol generates free radicals and conjugates to tyrosine residues in proteins more efficiently and selectively than the previously reported BP1 .

HY-Y0525

AAPH 2 Publications Verification 2,2'-Azodiisobutyramidine dihydrochloride	Reactive Oxygen Species (ROS)	Inflammation/Immunology
AAPH (2,2'-Azodiisobutyramidine dihydrochloride) has an effect of radical generation. AAPH induces oxidative stress and erythrocyte hemolysis . AAPH decomposes at 37°C to generate an alkyl radical, is used as an initiator. In the presence of oxygen, these alkyl radicals will be converted to peroxyl radicals that can cause lipid peroxidation and loss of erythrocyte membrane integrity, which could ultimately lead to hemolysis .

HY-121137

BMPO 1 Publications Verification BocMPO	Reactive Oxygen Species (ROS)	Others
BMPO (BocMPO) is a cell-permeable superior spin trap with favorable chemical and spectroscopic features. BMPO (BocMPO) can be used for detecting thiyl radicals, hydroxyl radicals, superoxide anions and glutathiyl radicals .

HY-W020183

γ-Terpinene	Environmental Pollutants Fungal Bacterial	Neurological Disease
γ-Terpinene, a monoterpene, is an orally active antioxidant compound which can scavenge radicals directly. γ-Terpinene has potent antinociception activity. γ-Terpinene exhibits antimicrobial efficacy against various bacteria and fungi .

HY-164008

DTUN	Ferroptosis	Others
DTUN is a lipophilic hyponitrite radical initiator and can initiates lipid peroxidation. DTUN is a tool for research of ferroptosis .

HY-129109

NBD-Pen	Fluorescent Dye	Inflammation/Immunology Cancer
NBD-Pen is the first fluorescence probe for lipid radicals with high selectivity and sensitivity (λ_ex: 470 nm, λ_em: 530 nm). NBD-Pen specifically detects lipid derived radicals over other reactive species present in biological systems, including H₂O₂, ClO ^-, O₂ ^-?, and ?OH. NBD-Pen directly detects lipid radicals in living cells by turn-on fluorescence. NBD-Pen decreases inflammation, apoptosis, and oxidative stress markers. NBD-Pen can be studied in various disease models such as hepatic carcinoma .

HY-135152

CYPMPO	Reactive Oxygen Species (ROS)	Cancer
CYPMPO is a spin-trapping reagent. CYPMPO, a cyclic DEPMPO-type nitrone, is evaluated for spin-trapping capabilities toward hydroxyl and superoxide radicals. anti-oxidant and anti-tumor?activity .

HY-N3220

Myricetin 3-O-galactoside 1 Publications Verification	Xanthine Oxidase	Metabolic Disease
Myricetin 3-O-galactoside inhibits xanthine oxidase (XO) activity, lipid peroxidation and scavenges the free radical. Myricetin 3-O-galactoside inhibits lipid peroxidation with an IC₅₀ of 160 μg/mL. Antioxidant activity .

HY-D1459

BODIPY 665/676	Fluorescent Dye	Metabolic Disease
BODIPY 665/676 is a lipophilic radical-sensitive fluorescent probe that can be used to study radical-driven lipid autoxidation (Ex/Em=665/676 nm) .

HY-23033

Tempone-H 1 Publications Verification	Biochemical Assay Reagents	Neurological Disease
Tempone-H may be used as a spin trap in chemical and biological systems to quantify peroxynitrite and superoxide radical formation. Ferric and cupric ions are effective oxidants of Tempone-H .

HY-W250971

*16-Doxylstearic acid (Free radical)* 16-DSA (Free radical)	Biochemical Assay Reagents	Others
16-Doxylstearic acid (16-DSA) (Free radical) is a form of stearic acid containing a 4,4-dimethyl-3-oxazolidinyloxy (DOXYL) group that forms a hydrophobic spin label. 16-Doxylstearic acid is often used to study on membrane fluidity .

HY-130015

HKSOX-1 (5/6-mixture) 2 Publications Verification	Reactive Oxygen Species (ROS)	Others
HKSOX-1 (5/6-mixture) is a fluorescent probe which is used for imaging and detection of endogenous superoxide in live cells and in vivo. HKSOX-1 (5/6-mixture) exhibits excellent selectivity and sensitivity towards superoxide anion radical (Ex/Em = 509/534 nm) .

HY-130017

HKSOX-1r (5/6-mixture)	Reactive Oxygen Species (ROS)	Others
HKSOX-1r (5/6-mixture) is a fluorescent probe which is used for imaging and detection of endogenous superoxide in live cells and in vivo. HKSOX-1r (5/6-mixture) exhibits excellent selectivity and sensitivity towards superoxide anion radical .

HY-N4177

Rubrofusarin gentiobioside	Others	Metabolic Disease
Rubrofusarin gentiobioside is isolated from the seeds of Cassia tora L. Rubrofusarin gentiobioside has a radical scavenging effect .

HY-W098021

2,2-Dimethoxy-2-phenylacetophenone Photoinitiator-651	Biochemical Assay Reagents	Others
2,2-Dimethoxy-2-phenylacetophenone is a hydrophobic benzoin ether-based free radical photoinitiator. 2,2-Dimethoxy-2-phenylacetophenone undergoes α-cleavage upon UV irradiation to generate benzoyl and substituted benzyl free radicals, thereby initiating photopolymerization reactions. 2,2-Dimethoxy-2-phenylacetophenone serves as a hydrophobic free radical photoinitiator for the photopolymerization of acrylamide and trimethylolpropane triacrylate in specific systems .

HY-129242

Tempone 4-Oxo-Tempo	SOD	Others
Tempone (4-Oxo-Tempo) is a stable water-soluble nitro radical. Tempone is widely used as a contrast agent for metabolic activity and hypoxic sensitivity in electron spin resonance spectroscopy, magnetic resonance imaging and dynamic nuclear polarization. Tempone reduces superoxide radicals by mimicking the activity of superoxide dismutase (SOD), thereby reducing the formation of hydroxyl radicals and peroxynitrites. Tempone can be used in the study of ischemia-reperfusion injury and acute renal failure .

HY-114713

POBN 4-POBN	Biochemical Assay Reagents	Others
POBN (4-POBN) is a cell permeable, hydrophilic spin trap that can be used to detect free radical adducts .

HY-W087905

2,3-Dimethyl-2,3-diphenylbutane	Biochemical Assay Reagents	Others
2,3-Dimethyl-2,3-diphenylbutane is a minor product formed during the thermal decomposition of dicumyl peroxide (DCP) in cumene, generated through radical coupling reactions. As an initiator capable of producing free radicals, 2,3-dimethyl-2,3-diphenylbutane promotes cross-linking or decomposition processes via initiating free radical reactions in fields such as polymer polymerization (e.g., modification of polyphenylene oxide processing), organic synthesis (e.g., DCP decomposition reactions), and coal processing (e.g., oxidation stabilization of coal tar pitch), thereby enhancing material properties or reaction efficiency .

HY-N0499A

Cyanidin	Prostaglandin Receptor	Inflammation/Immunology
Cyanidin is an orally active antioxidant and enzyme inhibitor. Cyanidin has IC₅₀ values of 90 μM and 60 μM against PGHS-1 and PGHS-2, respectively. Cyanidin exhibits excellent antioxidant and anti-inflammatory activities, scavenges free radicals, inhibits lipid peroxidation, and protects DNA from cleavage. Cyanidin can be used in the research of inflammatory diseases .

HY-N7692

Polyporusterone A	Others	Others
Polyporusterone A is a triterpene carboxylic acid isolated from Polyporus umbellatus Fries. Polyporusterone A has inhibitory effect on free radical-induced lysis of red blood cells (hemolysis) .

HY-N2307A

Lirinidine (+)-Lirinidine	Others	Cancer
Lirinidine ((+)-Lirinidine) is an alkaloid isolated from the leaves of L. tulipifera and has antioxidant and anticancer activities. Lirinidine exhibits medium ferric reducing power activity and minor radical scavenging activity in vitro. Lirinidine can be used for cosmetic research .

HY-120976

DEPMPO	Biochemical Assay Reagents	Cancer
cDEPMPO is a potent anticancer proagent. High concentrations of DEPMPO spin-trap the ·OH radical together with aryl radicals arising from one-electron reduced BTO (benzotriazine 1,4-di-N-oxide) compounds .

HY-N4168B

Methyl chlorogenate	Others	Cancer
Methyl chlorogenate is an antioxidant, and has radical scavenging activity. Methyl chlorogenate is an anti-inflammatory agent. Methyl chlorogenate also inhibits hepatocellular carcinoma (HCC) cell proliferation and metastasis .

HY-W011875

2-Isopropylthioxanthone	Biochemical Assay Reagents	Others
2-Isopropylthioxanthone is a photoinitiator that is widely used in printing ink of packaging materials. 2-Isopropylthioxanthone triggers the radical polymerization of the acrylic component of inks, thus causing the liquid ink film to dry .

HY-N8194

Syringetin-3-O-glucoside Syringetin 3-O-β-D-glucoside	Others	Neurological Disease
Syringetin-3-O-glucosid (Syringetin 3-O-β-D-glucoside), a flavonol glycoside, shows relatively weak DPPH and ABTS radical scavenging activity .

HY-N3985

Gyrophoric acid	Others	Cancer
Gyrophoric acid is a good ultraviolet filter in lichen populations. Gyrophoric acid shows *DPPH radical* scavenging** activity with an IC₅₀ value of 105.75 μg/ml .

HY-N7693

Polyporusterone B 1 Publications Verification	Others	Others
Polyporusterone B is a triterpene carboxylic acid isolated from Polyporus umbellatus Fries. Polyporusterone B has inhibitory effect on free radical-induced lysis of red blood cells (hemolysis) .

HY-106408

Nelonemdaz Salfaprodil free base; Neu2000	iGluR	Neurological Disease
Nelonemdaz (Salfaprodil free base) is an NR2B-selective and uncompetitive antagonist of N-methyl-D-aspartate (NMDA). Nelonemdaz is also a free radical scavenger. Nelonemdaz has excellent neuroprotection against NMDA- and free radical-induced cell death .

HY-N9447

Norbergenin 1 Publications Verification	Reactive Oxygen Species (ROS)	Neurological Disease
Norbergenin, the O-demethyl derivative of bergenin, shows moderate antioxidant activity (IC₅₀ 13 μM in DPPH radical scavenging; 32 μM in superoxide anion scavenging) .

HY-W129155

9,10-Dihydroacridine	Drug Intermediate	Others
9,10-Dihydroacridine is a chain-terminating antioxidant that can inhibit lipid peroxidation by capturing peroxide free radicals (LOO•) .

HY-N9895

3,5-Dicaffeoyl-epi-quinic acid	Others	Infection Inflammation/Immunology
3,5-Dicaffeoyl-epi-quinic acid can be extracted from Chrysanthemum morifolium. 3,5-Dicaffeoyl-epi-quinic acid has antioxidant activities. 3,5-Dicaffeoyl-epi-quinic acid can scavenge DPPH radical and superoxide anion radical, with IC₅₀s of 5.6 and 2.9 μg/mL respectively .

HY-N8219

Isoarundinin II	Reactive Oxygen Species (ROS)	Inflammation/Immunology
Isoarundinin II is a bibenzyl compound found in the pseudobulbs of Pleione grandiflora (Rolfe) Rolfe. Isoarundinin II scavenges DPPH free radicals .

HY-111523

Isomahanine	p38 MAPK Apoptosis Autophagy Caspase	Metabolic Disease
Isomahanine, carbazole alkaloid, is an antioxidative agent. Isomahanine has DPPH radical scavenging activity with an IC₅₀ value of 24 μM .

HY-N3596

Cleomiscosin C Aquillochin	Others	Inflammation/Immunology
Cleomiscosin C (Aquillochin) can be isolated from Aquilaria agallocha. Cleomiscosin C has antioxidant activity. Cleomiscosin C inhibits LDL oxidation and free radicals generation .

HY-N8042

Erigeside I	Others	Others
Erigeside I is a free radical scavenger isolated from Erigeron breviscapus .

HY-N10176

D-Isofloridoside	Reactive Oxygen Species (ROS) MMP	Cardiovascular Disease
D-Isofloridoside, one of the polysaccharide precursors, has the activity of scavenging free radicals, inhibiting ROS expression, and inhibiting MMP-2 and MMP-9 .

HY-W274194

Antioxidant agent-7	Reactive Oxygen Species (ROS)	Others
Antioxidant agent-7 (SD-7) is a benzodiazepine derivative with antioxidant activity with an IC₅₀ value of 470 nM to scavenge DPPH (2,2-diphenyl-1-picrylhydrazyl) free radical .

HY-W002773

Methyl isovanillate	Endogenous Metabolite	Others
Methyl isovanillate is a secondary metabolite isolated from Vitex agnus-castus. Methyl isovanillate does not exhibit significant activity in the DPPH free radical* scavenging experiment* .

HY-N15684

Rhodoxanthin	Others	Metabolic Disease
Rhodoxanthin is a carotenoid. Rhodoxanthin exerts antioxidant activity via free radical scavenging and lipid peroxidation inhibition. Rhodoxanthin is promising for research of oxidative stress-related diseases (e.g., UV-induced skin damage) .

HY-N8955

Maritimein	Reactive Oxygen Species (ROS)	Inflammation/Immunology
Maritimein is an aurone glucoside and antioxidant with free radical scavenger activity, found in Coreopsis tinctoria Nutt.Maritimein scavenges ABTS•+ radical cations .

HY-N15703

Norisocorydine (+)-Norisocorydine	Others	Neurological Disease
Norisocorydine ((+)-Norisocorydine) is an aporphine alkaloid with antinociceptive and radical scavenging effects. Norisocorydine shows a SC₅₀ of 14.1 μg/mL in DPPH radical scavenging test. Norisocorydine exhibits antinociceptive ability in mice .

HY-106408A

Nelonemdaz potassium Salfaprodil; Neu2000 potassium	iGluR	Neurological Disease
Nelonemdaz (Salfaprodil) potassium is an NR2B-selective and uncompetitive antagonist of N-methyl-D-aspartate (NMDA). Nelonemdaz potassium is also a free radical scavenger. Nelonemdaz potassium has excellent neuroprotection against NMDA- and free radical-induced cell death .

HY-N16406

Auroglaucin	SOD	Metabolic Disease
Auroglaucin is a potent antioxidant. Auroglaucin shows 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging capacity and superoxide radical scavenging activity with EC₅₀ value of 74.6, 12.3 µM, respectively. Auroglaucin shows low activity for inhibiting the autoxidation of docosahexaenoic acid (DHA) .

HY-N10020

Patulitrin	Lipoxygenase	Inflammation/Immunology
Patulitrin has scavenging effect in the DPPH radical. Patulitrin inhibits soybean lipoxygenase. Patulitrin also has antihypertensive effect. Patulitrin is an antioxidant flavonoid that can be isolated from Anthemis tinctoria .

HY-N15440

Mutatochrome Citroxanthin	Reactive Oxygen Species (ROS) Endogenous Metabolite	Inflammation/Immunology Cancer
Mutatochrome (Citroxanthin) is a naturally occurring carotenoid pigment found in certain plants. Mutatochrome has antioxidant property to help protect cells from damage caused by free radicals. Mutatochrome can be used for anti-inflammatory and anticancer study .

HY-W015913R

Pyruvic acid sodium (Standard) 5+ Cited Publications Sodium 2-oxopropanoate (Standard); Acetylformic acid sodium (Standard)	Reference Standards Reactive Oxygen Species (ROS) Endogenous Metabolite	Metabolic Disease
Sodium 2-oxopropanoate (Standard) is the analytical standard of Sodium 2-oxopropanoate. This product is intended for research and analytical applications. Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS .

HY-N3554

Catechin-7-O-β-D-xylopyranoside (+)-Catechol 7-β-D-xylopyranoside	Others	Others
Catechin-7-O-β-D-xylopyranoside is an antioxidant compound with strong DPPH free radical scavenging ability. Catechin-7-O-β-D-xylopyranoside can be extracted from birch inner bark and nepeta stem bark .

HY-W250973

Galvinoxyl free radical	Biochemical Assay Reagents	Others
Galvinoxyl free radical is a stable organism with free radicals .

Cat. No.	Product Name

HY-L037

Antioxidant Compound Library

2,332 compounds

Oxidative stress is an imbalance of free radicals and antioxidants in the body, which can lead to cell and tissue damage. Oxidative stress can be responsible for the induction of several diseases, both chronic and degenerative, as well as speeding up body aging process and cause acute pathologies. Antioxidants are a class of compounds able to counteract oxidative stress and mitigate its effects on individuals’ health, gained enormous attention from the biomedical research community. Antioxidants have long been substantial and amenable therapeutic arsenals for multifarious diseases such as AD and cancer.

MCE Antioxidant Compound Library contains 2,332 compounds that act as antioxidants for high throughput screening (HTS) and high content screening (HCS). This library is a useful tool for discovery new antioxidants and oxidative stress research.

HY-L144

Mitochondrial Protection Compound Library

1,014 compounds

Normal mitochondrial function is critical for maintaining cellular homeostasis because mitochondria produce ATP and are the major intracellular source of free radicals. Cellular dysfunctions induced by intracellular or extracellular insults converge on mitochondria and induce a sudden increase in permeability on the inner mitochondrial membrane, the so-called mitochondrial membrane permeability transition (MMPT). MMPT is caused by the opening of pores in the inner mitochondrial membrane, matrix swelling, and outer membrane rupture. The MMPT is an endpoint to initiate cell death because the pore opening together with the release of mitochondrial cytochrome c activates the apoptotic pathway of caspases.

The normal operation of mitochondrial function is important for maintaining normal cell death and treatment of mitochondrial diseases. MCE offers a unique collection of 1,014 compounds with identified and potential mitochondrial protective activity. MCE Mitochondrial Protection Compound Library is critical for drug discovery and development.

HY-L178

Radioprotector Library

2,846 compounds

Radiation sickness is a general term for various types and degrees of damage (or disease) occurring in the human body after exposure to ionizing radiation. Although small amounts of ionizing radiation can also cause the body to produce free radicals and ROS, causing oxidative stress, resulting in DNA damage and chromosomal aberration. Radioprotector are compounds with radiation protection that can be used to prevent/protect non-tumor cells from the harmful effects of radiation. Radioprotective compounds can prevent the damage of radioactive substances to the human body and reduce the clinical symptoms of various radioactive diseases. In addition, radioprotectors can protect normal cells from damage during radiation therapy. The ideal anti-radiation drug should not affect the sensitivity of tumor cells to radiation therapy while protecting normal cells.

MCE designs a unique collection of 2,846 radioprotectors. Radioprotector Library is an effective tool for acute Radiation Syndrome, drug combination research with radiation drugs.

Cat. No.	Product Name	Type

HY-D1301

BODIPY 581/591 C11

Maximum Cited Publications

135 Publications Verification

Fluorescent Dye

BODIPY 581/591 C11 is a BODIPY borofluoroprene derivative with good light stability and low fluorescence artifacts. BODIPY 581/591 C11 can be used for study lipid peroxidation and antioxidant properties in living cells, or detect ferroptosis by reaction with hydroxyl radicals. BODIPY 581/591 C11 is emitted at 591 nm (reduced prototype), or redshifted to 510 nm (oxidized type). The excitation wavelengths were 581 nm (reduced prototype) and 500 nm (oxidized type) .

HY-D1168

Oil Red O 10+ Cited Publications	Fluorescent Dye
Oil Red O is a fat-soluble diazol dye, with a maximum absorption at 518 nm. Oil Red O stains neutral lipids and cholesteryl esters but not biological membranes. Oil Red O can be used for detecting and quantifying hepatic steatosis in mouse liver biopsies. Oil Red O staining efficiently helps to visualize the radical changes that occur in tissues as metabolic disease occurs and progresses .

HY-111330

Hydroxyphenyl Fluorescein

10+ Cited Publications

HPF; 3'-p-(Hydroxyphenyl) fluorescein

Fluorescent Dye

Hydroxyphenyl Fluorescein (HPF) is a stable ROS fluorescent probe dye. Hydroxyphenyl Fluorescein has stronger specificity and stability than H2DCFDA (HY-D0940). Hydroxyphenyl Fluorescein can produce strong green fluorescence through hydroxyl radical reaction with intracellular peroxynitroso. Hydroxyphenyl Fluorescein can be applied for fluorescence microscopy, high-throughput imager, luciferase microplate reader or flow cytometry. Ex/Em=490/515 nm .

HY-W011664

1,3-Diphenylisobenzofuran

25+ Cited Publications

DPBF

Fluorescent Dye

1,3-Diphenylisobenzofuran (DPBF) has been developed as a selective probe for the detection and quantitative determination of hydrogen peroxide in samples containing different reactive nitrogen and oxygen species (RNOS). DPBF is a fluorescent probe which, for almost 20 years, was believed to react in a highly specific manner toward some reactive oxygen species such as singlet oxygen and hydroxy, alkyloxy or alkylperoxy radicals .

HY-D0367

Fluorescent Brightener 28

1 Publications Verification

Calcofluor White M2R

Fluorescent Dye

Fluorescent brightener 28 is a fluorescent whitening agent commonly used in the padding process of the textile industry. Fluorescent brightener 28 is capable of staining polysaccharides such as cellulose, and when the plasma membrane ruptures, it also weakly stains the cytoplasm and strongly stains the cell nucleus. Additionally, Fluorescent brightener 28 can be utilized to detect intracellular chitin in living cells. Fluorescent Brightener 28 also is a visible light emitting diode (LED)-light sensitive photoinitiator for free radical photopolymerizations .

HY-D0720

Lucigenin 5+ Cited Publications NSC-151912; L-6868	Fluorescent Dye
Lucigenin is a chemiluminescence probe. Lucigenin can be used to detect the production of endogenous superoxide anion radical (O ^2-). Lucigenin is extremely sensitive to chloride ions, while it combined with chloride ions, the fluorescence will be quenched. Lucigenin also can be used as a chloride indicator. Ex/Em=455/505 nm .

HY-DY1022

BODIPY 581/591 C11 (solution)

Fluorescent Dye

BODIPY 581/591 C11 (solution) is a BODIPY borofluoroprene derivative with good light stability and low fluorescence artifacts. BODIPY 581/591 C11 can be used for study lipid peroxidation and antioxidant properties in living cells, or detect ferroptosis by reaction with hydroxyl radicals. BODIPY 581/591 C11 is emitted at 591 nm (reduced prototype) , or redshifted to 510 nm (oxidized type). The excitation wavelengths were 581 nm (reduced prototype) and 500 nm (oxidized type) .
Solvent and concentration: DMSO: 2 mM

HY-123645

Rhodamine B hydrazide

1 Publications Verification

Fluorescent Dye

Rhodamine B hydrazide is a fluorescent derivative based on rhodamine B, containing the spirocyclic structure of Rhodamine B (HY-Y0016), which can be used to detect copper ions (Cu ²⁺), mercury ions, peroxynitrite, hydroxyl radicals and nitric oxide (NO) .
Excitation/emission wavelength:
Conventional detection: 510/578 nm.
Sulfite detection: 554 nm absorption, 574 nm emission (due to the formation of Rhodamine B fluorescent product).

HY-D0168

Orcinol

3,5-Dihydroxytoluene

Fluorescent Dye

Orcinol (3,5-Dihydroxytoluene) is an organic compound used in biological dyeing and proteomics research. Orcinol inhibits melanogenesis in B16F10 cells by upregulating the MAPK/ERK signaling pathway, and suppresses the expression of MITF, tyrosinase (TYR), TRP1, and DCT. Orcinol exhibits certain DPPH radical scavenging activity. In addition, Orcinol can alter nitrogen balance in animals. Orcinol holds promise for research in cancer and metabolic diseases .

HY-129109

NBD-Pen

Fluorescent Dye

NBD-Pen is the first fluorescence probe for lipid radicals with high selectivity and sensitivity (λ_ex: 470 nm, λ_em: 530 nm). NBD-Pen specifically detects lipid derived radicals over other reactive species present in biological systems, including H₂O₂, ClO ^-, O₂ ^-?, and ?OH. NBD-Pen directly detects lipid radicals in living cells by turn-on fluorescence. NBD-Pen decreases inflammation, apoptosis, and oxidative stress markers. NBD-Pen can be studied in various disease models such as hepatic carcinoma .

HY-D1459

BODIPY 665/676	Fluorescent Dye
BODIPY 665/676 is a lipophilic radical-sensitive fluorescent probe that can be used to study radical-driven lipid autoxidation (Ex/Em=665/676 nm) .

HY-117401

5-Dodecanoylaminofluorescein

Fluorescent Dye

5-Dodecanoylaminofluorescein is an amphipathic (amphoteric) fluorescent probe (Ex/Em = 485 nm/515-535 nm), which consists of a hydrophilic fluorescein core and a hydrophobic dodecanoyl group (C12 fatty acid chain) linked by an amide bond. 5-Dodecanoylaminofluorescein is mainly used as an interface-localized radical trapping/indicator probe. Dodecanoylaminofluorescein can be used for the determination of the antioxidant properties of emulsions, or can serve as a lipophilic drug model for the study of passive skin penetration when encapsulated in tyrosine-derived nanospheres .

HY-115691

STY-BODIPY Styrene-BODIPY; Styrene-Conjugated BODIPY	Fluorescent Dye
STY-BODIPY (Styrene-BODIPY; Styrene-Conjugated BODIPY) is a styrene-conjugated fluorescent probe used to measure the activity of radical-trapping antioxidants (RTAs)> .

HY-130015

HKSOX-1 (5/6-mixture) 2 Publications Verification	Fluorescent Dye
HKSOX-1 (5/6-mixture) is a fluorescent probe which is used for imaging and detection of endogenous superoxide in live cells and in vivo. HKSOX-1 (5/6-mixture) exhibits excellent selectivity and sensitivity towards superoxide anion radical (Ex/Em = 509/534 nm) .

HY-130017

HKSOX-1r (5/6-mixture)	Fluorescent Dye
HKSOX-1r (5/6-mixture) is a fluorescent probe which is used for imaging and detection of endogenous superoxide in live cells and in vivo. HKSOX-1r (5/6-mixture) exhibits excellent selectivity and sensitivity towards superoxide anion radical .

HY-130025

HKOCl-3 2 Publications Verification	Fluorescent Dye
HKOCl-3 is a highly sensitive and selective fluorescent probe for detecting hypochlorous acid.E_x: 490 nm; E_m 527 nm .

HY-W103047

1-Pyrenebutyric acid

Fluorescent Dye

1-Pyrenebutyric acid is a fluorescence probe whose fluorescence lifetime depends on local oxygen and free radical concentrations. 1-Pyrenebutyric acid is used in fluorescence determination of DNA. 1-Pyrenebutyric acid can be used as a linker for biomolecules to form a self-assembled monolayer on grapheme. 1-Pyrenebutyric acid can also be used for the measurement of free radicals in solution and in living cells .

HY-D1159

HKOH-1r 5+ Cited Publications	Fluorescent Dye
HKOH-1r is a highly sensitive green fluorescent probe for the specific detection of ·OH in living cells with a maximum excitation wavelength and emission wavelength of 500 nm and 520 nm, respectively .

HY-D1151

HKOH-1 3 Publications Verification	Fluorescent Dye
HKOH-1 is a highly sensitive green fluorescent probe for the specific detection of ·OH in living cells with a maximum excitation wavelength and emission wavelength of 500 nm and 520 nm, respectively .

HY-100512

Benzenepentacarboxylic Acid Pentacarboxybenzene	Fluorescent Dye
Benzenepentacarboxylic acid is a fluorescent dye that detects and scavenge HO radicals.

HY-DY1035

Hydroxyphenyl Fluorescein (solution)

Fluorescent Dye

Hydroxyphenyl Fluorescein (HPF) (solution) is a stable ROS fluorescent probe dye. Hydroxyphenyl Fluorescein has stronger specificity and stability than H2DCFDA (HY-D0940). Hydroxyphenyl Fluorescein can produce strong green fluorescence through hydroxyl radical reaction with intracellular peroxynitroso. Hydroxyphenyl Fluorescein can be applied for fluorescence microscopy, high-throughput imager, luciferase microplate reader or flow cytometry. Ex/Em=490/515 nm .
Solvent and concentration: DMSO: 10 mM

HY-DY1053

1,3-Diphenylisobenzofuran (solution)

Fluorescent Dye

1,3-Diphenylisobenzofuran (DPBF) (solution) has been developed as a selective probe for the detection and quantitative determination of hydrogen peroxide in samples containing different reactive nitrogen and oxygen species (RNOS). DPBF is a fluorescent probe which, for almost 20 years, was believed to react in a highly specific manner toward some reactive oxygen species such as singlet oxygen and hydroxy, alkyloxy or alkylperoxy radicals .
Solvent and concentration: DMSO: 10 mM
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

HY-D0113

7-Hydroxy-4-methyl-2(1H)-quinolone	Fluorescent Dye
7-Hydroxy-4-methyl-2(1H)-quinolone (compound 2b) is a fluorescent hydroxylated product. 7-Hydroxy-4-methyl-2(1H)-quinolone can be used for detecting hydroxyl radicals of DNA damage .

HY-119987

Sudan orange G SOG	Fluorescent Dye
Sudan orange G is an azo dye. Sudan orange G, after enzymatic oxidation, generates oligomers and even polymers through free radical coupling reactions .

HY-119987R

Sudan orange G (Standard) SOG (Standard)	Fluorescent Dye
Sudan orange G (Standard) is the analytical standard of Sudan orange G. This product is intended for research and analytical applications. Sudan orange G is an azo dye. Sudan orange G, after enzymatic oxidation, generates oligomers and even polymers through free radical coupling reactions .

HY-W127725

Thymolphthalexon tetrasodium

Fluorescent Dye

Thymolphthalexon (tetrasodium) is an organic compound commonly used as a reagent in biochemical assays. It belongs to the family of thioxanthone derivatives and has strong antioxidant properties. Thymolphthalexon has several applications in the study of free radical response, oxidative stress, and aging. In addition, it can be used as a photosensitizer in photodynamic therapy for the improvement of cancer and other diseases.

HY-D3449

8-(9-Bromoanthracene)-BODIPY 505/515	Fluorescent Dye
8-(9-Bromoanthracene)-BODIPY 505/515 is a fluorescence turn-on probe with selective fluorescence turn-on response towards hydroxyl radical. 8-(9-Bromoanthracene)-BODIPY 505/515 can be used to detect reactive oxygen/nitrogen species (ROS/RNS) . (Ex/Em = 505/515 nm)

HY-D3225

MD-B

Fluorescent Dye

MD-B is a •OH Fluorescent probe with blood-brain barrier permeability. MD-B undergoes single-electron oxidation by hydroxyl radicals (•OH), which triggers fluorescence enhancement and enables in-situ imaging of •OH. MD-B allows imaging analysis of hydroxyl radicals (•OH) in the mouse brain, revealing a positive correlation between elevated •OH levels and the severity of depressive phenotypes. MD-B can be used in depression-related research .

HY-100512R

Benzenepentacarboxylic Acid (Standard) Pentacarboxybenzene (Standard)	Fluorescent Dye
Benzenepentacarboxylic Acid (Standard) is the analytical standard of Benzenepentacarboxylic Acid (HY-100512). This product is intended for research and analytical applications. Benzenepentacarboxylic acid is a fluorescent dye that detects and scavenge HO radicals.

HY-D3315

Rhodamine B carbohydrazide	Fluorescent Dye
Rhodamine B carbohydrazide is a fluorescent derivative based on Rhodamine B (HY-Y0016) that contains the spirocyclic structure of Rhodamine B; it can be used for the detection of copper ions (Cu ²⁺), mercury ions, peroxynitrite, hydroxyl radicals, and nitric oxide (NO).

HY-D3303

8-iso Prostaglandin A2-biotin 8-iso PGA2-biotin	Fluorescent Dye
8-iso Prostaglandin A2-biotin (8-iso PGA2-biotin) is an affinity probe conjugated with biotin, consisting of 8-iso Prostaglandin A2 (8-iso PGA2). 8-iso PGA2 is an isoprostaglandane produced by the radical-catalyzed peroxidation of arachidonic acid. 8-iso Prostaglandin A2-biotin can be detected by its interaction with a biotin ligand .

Cat. No.	Product Name	Type

HY-Y0320C

Dimethyl sulfoxide

30+ Cited Publications

DMSO

Biochemical Assay Reagents

Dimethyl sulfoxide (DMSO) is an aprotic solvent that can dissolve water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and has the ability to rapidly penetrate or enhance the penetration of other substances through biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity .
Low endotoxin, can be used in various biochemical experiments such as drug dissolution.

HY-Y0320

Dimethyl sulfoxide, meets analytical specification of Ch.P.

Maximum Cited Publications

346 Publications Verification

DMSO, meets analytical specification of Ch.P.

Biochemical Assay Reagents

Dimethyl sulfoxide (DMSO), meets analytical specification of Ch.P. is an aprotic solvent that dissolves polar and non-polar compounds, including water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and can rapidly penetrate or enhance the penetration of other substances into biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity. Dimethyl sulfoxide also exhibits antifreeze and antibacterial properties .
MCE provides Dimethyl sulfoxide that complies with the inspection standards (Ch.P) of Part 4 of the Chinese Pharmacopoeia (2020 Edition). Amicrobic, low endotoxin, can be used in various biochemical experiments such as drug dissolution.

HY-D0187

L-Glutathione reduced Maximum Cited Publications 54 Publications Verification GSH; γ-L-Glutamyl-L-cysteinyl-glycine	Biochemical Assay Reagents
L-Glutathione reduced (GSH; γ-L-Glutamyl-L-cysteinyl-glycine) is an endogenous antioxidant and is capable of scavenging oxygen-derived free radicals.

HY-44076

LAP

4 Publications Verification

Lithium phenyl-2,4,6-trimethylbenzoylphosphinate

Biochemical Assay Reagents

LAP (Lithium phenyl-2,4,6-trimethylbenzoylphosphinate) is a free radical initiator. The free radicals produced by LAP under bioprinting conditions are potentially cytotoxic and mutagenic. In addition, the concentration of LAP affects the mechanical strength of 3D printed scaffolds. Generally, the concentration range of LAP used for curing is 0.05%-1%. The elastic modulus produced at a concentration of 0.1% is the highest, with enhanced mechanical properties and excellent biocompatibility .

HY-W015913

Pyruvic acid sodium 15+ Cited Publications Sodium 2-oxopropanoate; Acetylformic acid sodium	Biochemical Assay Reagents
Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS .

HY-108749

Olive oil

5+ Cited Publications

Cropure OL

Biochemical Assay Reagents

Olive oil (Cropure OL) is an oleaginous compound found in the fruit of the Olea europaea tree . Olive oil contains many phenolic components and exerts antioxidant activity. Olive oil exhibits hydroxyl radical scavenging, platelet aggregation inhibition and xanthine oxidase inhibitory activity. Olive oil can promote wound healing and relieve inflammation. Olive oil can be used for the research of inflammation, cancer, metabolic and cardiovascular disease, such as diabetic foot ulcers and inflammatory bowel disease .

HY-B2196

Gastric mucin 3 Publications Verification	Biochemical Assay Reagents
Gastric mucin is a glycoprotein with natural antibiotic function. Gastric mucin against Helicobacter pylori infection. Gastric mucin effectively scavenges hydroxyl radical. Gastric mucin play a major role in the protection of the gastrointestinal tract from acid, proteases, pathogenic microorganisms, and mechanical trauma .

HY-134816

D-Glucan

Biochemical Assay Reagents

D-Glucan is an orally effective Dectin-1 receptor immune activator with antioxidant properties (reducing TNF-α). D-Glucan activates macrophages and neutrophils to scavenge free radicals, inhibit oxidative stress and inflammatory responses, and improve insulin sensitivity. D-Glucan promotes glycolysis by enhancing the activity of the antioxidant enzyme glutathione, inhibiting gluconeogenesis and activating GK. D-Glucan can be used in the research of liver damage protection (antagonizing Acetaminophen (HY-66005) toxicity), radiation protection (synergistic with vitamin E) and diabetes (improving glucose metabolism) .

HY-W013508

I2959 2 Publications Verification	Biochemical Assay Reagents
I2959 is widely used as a photoinitiator for photochemical cross-linking of hydrogels, and the combination of I2959 and CMA hydrogel has been used as a bio-ink for biological 3D printing applications. In addition, I2959 has a high free radical generation efficiency and is cytotoxic to rapidly dividing cell lines .

HY-D0187R

L-Glutathione reduced (Standard) GSH (Standard); γ-L-Glutamyl-L-cysteinyl-glycine (Standard)	Biochemical Assay Reagents
L-Glutathione reduced (Standard) is the analytical standard of L-Glutathione reduced. This product is intended for research and analytical applications. L-Glutathione reduced (GSH; γ-L-Glutamyl-L-cysteinyl-glycine) is an endogenous antioxidant and is capable of scavenging oxygen-derived free radicals.

HY-W002004

4-Amino-TEMPO

4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl

Biochemical Assay Reagents

4-Amino-TEMPO (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl) is a stable nitroxide radical and N-nucleophile based on TEMPO. 4-Amino-TEMPO has superoxide dismutase-mimetic activity, can protect cells from oxidative damage, and has radioprotective effects. 4-Amino-TEMPO is widely used in fields such as biomedicine, materials science, and industrial production. 4-Amino-TEMPO can be used as a spin label to detect free radicals, an oxidation catalyst in industrial production, and an antioxidant stabilizer for polymers, among others .

HY-15932

TOOS

TOOS sodium salt

Biochemical Assay Reagents

TOOS (TOOS sodium salt) is a highly water-soluble aniline derivative widely used in diagnostics and biological experiments. TOOS can be combined with 3-methyl-2-benzothiazolinone hydrazone hydrochloride (MBTH) to form a chromogenic system to measure oxidase activity. In the MBTH-TOOS chromogenic system, MBTH is catalytically oxidized to produce (-NH) free radicals, which react with TOOS to form colorless compounds. Furthermore, the colorless compound undergoes a disproportionation reaction to produce a blue-violet quinoid compound .

HY-Y0320GL

Dimethyl sulfoxide (GMP Like)

DMSO (GMP Like)

Biochemical Assay Reagents

Dimethyl sulfoxide (DMSO) (GMP Like) is the GMP Like class Dimethyl sulfoxide (HY-Y0320C). Dimethyl sulfoxide is an aprotic solvent that can dissolve water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide has a strong affinity for water and has the ability to rapidly penetrate or enhance the penetration of other substances through biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity .

HY-N9497

Galactinol

Biochemical Assay Reagents

Galactinol is a disaccharide carbohydrate serving as a galactosyl donor, which belongs to the raffinose family oligosaccharide pathway and acts as an important osmoprotectant. Galactinol not only induces disease resistance in plants against fungal and bacterial pathogens, but also significantly enhances plant tolerance to abiotic stresses such as drought, high salinity, low temperature and oxidative damage. In addition, Galactinol has the ability to scavenge hydroxyl radicals, can act as a signaling component for root colonization-induced systemic resistance, and is positively correlated with seed longevity in various crops, making it a potential biomarker for evaluating seed vigor. Therefore, Galactinol can be used in the research of various plant diseases including fungal leaf spot, bacterial angular leaf spot, gray mold and soft rot .

HY-W004761

Tetrahydroxydiboron

Hypodiboric acid

Biochemical Assay Reagents

Tetrahydroxydiboron acts as a hydrogel initiator and bioadhesion promoter, with broad-spectrum antibacterial activity, ROS scavenging capacity and osteogenic induction properties. Tetrahydroxydiboron initiates rapid gelation by generating free radicals through reactions with vinyl monomers and dissolved oxygen, and overcomes oxygen inhibition without deoxygenation or external triggers. Tetrahydroxydiboron achieves strong bioadhesion through interaction with carboxymethyl chitosan. Tetrahydroxydiboron can be used in the research of periodontitis and related inflammatory diseases .

HY-W011426

Isopropyl palmitate

Propan-2-yl hexadecanoate

Biochemical Assay Reagents

Isopropyl palmitate is an fatty acid ester. Isopropyl palmitate can be used for design and characterization of bioactive bilayer films. The bilayer membrane not only has the ability to scavenge free radicals and inhibit lipid peroxidation, but also can inhibit the growth of known foodborne pathogens. Isopropyl palmitate can be used as an excipient, such as lubricant, oily carrier, solvent, controlled-release transdermal film. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .

HY-W115721

Rhodizonic acid disodium

Sodium rhodizonate dibasic

Biochemical Assay Reagents

Rhodizonic acid disodium (Sodium rhodizonate dibasic) is a transition metal-dependent pro-oxidant and lead detection agent that induces reactive oxygen species generation, DNA damage, and inhibits Aconitase activity. Rhodizonic acid disodium generates superoxide anion radicals in an iron (II)-dependent manner, leading to aconitase inactivation. Rhodizonic acid disodium also triggers hydroxyl radical-mediated DNA strand breaks and 8-OHdG formation via copper ion reduction. Rhodizonic acid disodium reacts with lead to form a scarlet precipitate, with the color intensity proportional to lead content, enabling qualitative or quantitative analysis of lead. Rhodizonic acid disodium can also be used for real-time visualization of the dynamic process of lead sequestration in the plant rhizosphere and evaluation of the effects of environmental factors such as soil type on the stability of lead-sequestering structures .

HY-W034344

Sodium methanesulfonate

Biochemical Assay Reagents

Sodium methanesulfonate is a hygroscopic atmospheric aerosol, which typically forms from the reaction of methanesulfonic acid with sodium chloride or sea salt particles. Sodium methanesulfonate can serve as a substrate for oxidation reactions, undergoing heterogeneous oxidation by hydroxyl radicals at the air-aerosol interface, thereby initiating subsequent aerosol-phase chain reactions. Sodium methanesulfonate exhibits significant temperature-dependent deliquescence and efflorescence properties; particularly at lower temperatures relevant to the troposphere, its deliquescence and efflorescence relative humidity increase accordingly .

HY-W019885A

Sodium tripolyphosphate (STPP), 98% Sodium triphosphate pentabasic, 98%	Biochemical Assay Reagents
Sodium tripolyphosphate (STPP), 98% is an inorganic, non-toxic polyphosphate crosslinker, inducer and enhancer. Sodium tripolyphosphate (STPP), 98% induces the formation of unique needle-like microcrystals in sodium alginate-chitosan composite films. Sodium tripolyphosphate (STPP), 98% enhances the DPPH free radical scavenging activity of sodium alginate-chitosan composite films .

HY-B2162B

Chondroitin sulfate sodium (from bovine)

Chondroitin polysulfate sodium (from bovine)

Biochemical Assay Reagents

Chondroitin sulfate (Chondroitin polysulfate) sodium (from bovine)) is a sulfated linear polysaccharide extracted from bovine sources, belonging to glycosaminoglycans. Chondroitin sulfate sodium (from bovine) inhibits osteoclast-mediated bone resorption and exhibits antioxidant activity, which is negatively correlated with molecular weight. Chondroitin sulfate sodium (from bovine) can be used in studies related to osteoarthritis .

HY-172380A

PCL-PEG-PCL diacrylate (PCL average Mn800, PEG average Mn4000)	Biochemical Assay Reagents
PCL-PEG-PCL diacrylate (MW 800) is an amphiphilic triblock copolymer composed of PEG and two polycaprolactones (PCL). PCL-PEG-PCL diacrylate (MW 800) can be cross-linked by free radical polymerization and/or photopolymerization to form a cross-linked hydrogel network .

HY-W099538

Dilauryl thiodipropionate

Dilauryl 3,3'-Thiodipropionate

Biochemical Assay Reagents

Dilauryl thiodipropionate (DLTDP), which is a sulfur-containing antioxidant commonly used to stabilize polymers and plastics against degradation caused by heat, oxygen, and UV light, acts to scavenge free radicals and others that may cause polymer chain scission and cross-linked active substances, in addition, DLTDP has been used as an additive to lubricants, oils and other industrial fluids to improve their oxidation stability, the long hydrocarbon chain in DLTDP makes it low volatility and compatible with many materials and Good compatibility with substrates.

HY-W002805

2-Bromoisonicotinic acid 1 Publications Verification	Biochemical Assay Reagents
2-Bromoisonicotinic acid is a (hetero)aryl bromide building block and DNA-conjugated headpiece for photochemical C-H heteroarylation in DNA-encoded library synthesis. 2-Bromoisonicotinic acid generates a nucleophilic pyridyl radical intermediate. 2-Bromoisonicotinic acid, when conjugated to DNA, leaves electrophilic handles intact for subsequent library diversification .

HY-W002438

6-Hydroxyindole

Biochemical Assay Reagents

6-Hydroxyindole is an orally active, endogenous long-acting OATP1B1 inhibitor. 6-Hydroxyindole does not alter the cell surface expression or subcellular localization of OATP1B1. 6-Hydroxyindole protects cells against Ferroptosis. 6-Hydroxyindole possesses intrinsic radical-trapping antioxidant activity. 6-Hydroxyindole serves as a component of oxidative hair dyes. 6-Hydroxyindole can be used in research related to renal failure and neurodegenerative diseases .

HY-Y0320E

Dimethyl sulfoxide (suitable for HPLC)

Biochemical Assay Reagents

Dimethyl sulfoxide (suitable for HPLC) is an aprotic solvent that can dissolve water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and has the ability to rapidly penetrate or enhance the penetration of other substances through biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity. Dimethyl sulfoxide (suitable for HPLC) is suitable for HPLC .

HY-W145481A

D-Galacto-D-mannan

Carob galactomannan

Biochemical Assay Reagents

D-Galacto-D-mannan (Carob galactomannan) is an orally active Dectin-2 agonist. D-Galacto-D-mannan exerts antioxidant activity against hydroxyl radical generation. D-Galacto-D-mannan activates Dectin-2 to trigger downstream signaling pathways, promote the expression of immunoregulatory molecules, coordinate innate and adaptive immune responses, and inhibit excessive inflammatory responses by upregulating the expression of Sirtuin 1. When used as a vaccine adjuvant, D-Galacto-D-mannan induces cellular and humoral immune responses, promotes IFNγ secretion, increases antibody levels and virus neutralization titers, and elevates the levels of immunoglobulin G and A. D-Galacto-D-mannan can serve as an adjuvant for foot-and-mouth disease vaccines, enhance the vaccine-mediated ability of hosts to defend against viral infection in mice, and reduce local side effects at the inoculation site in pigs. D-Galacto-D-mannan can be used in the research of inflammatory and immune diseases, such as foot-and-mouth disease .

HY-W013677

4-Fluorobenzoic acid	Biochemical Assay Reagents
4-Fluorobenzoic acid is a drug intermediate that can be used to synthesize a series of hydrazone derivatives with antituberculosis activity and Schiff bases with DPPH radical scavenging activity .

HY-172380

PCL-PEG-PCL diacrylate (PCL Average Mn 200, PEG Average Mn 1000)	Biochemical Assay Reagents
PCL-PEG-PCL diacrylate (MW 800) is an amphiphilic triblock copolymer composed of PEG and two polycaprolactones (PCL). PCL-PEG-PCL diacrylate (MW 800) can be cross-linked by free radical polymerization and/or photopolymerization to form a cross-linked hydrogel network .

HY-42045

Pyrimidine-5-boronic acid pinacol ester

Biochemical Assay Reagents

Pyrimidine-5-boronic acid pinacol ester is a derivative of Boronic acid. Boronic acid is an intermediate commonly used in organic synthesis reactions and can be used as a key reagent in the Suzuki-Miyaura reaction. It generates organic free radicals through oxygen-mediated oxidation and exhibits potential mutagenic activity. Boronic acid is mainly used in research in the fields of drug synthesis and catalytic reactions. Pyrimidine-5-boronic acid pinacol ester serves as a building block in DNA-compatible one-pot click chemistry for synthesis of DNA-encoded libraries .

HY-Y0396

N-Hydroxyphthalimide

Biochemical Assay Reagents

N-Hydroxyphthalimide is a blocking agent and catalyst. N-Hydroxyphthalimide promotes oxidation reactions by generating PINO free radicals and activating hydrogen atom transfer processes. N-Hydroxyphthalimide reduces the expression of anti-apoptotic proteins Survivin and Bcl-xL and activates caspase 9 and caspase 3. N-Hydroxyphthalimide induces Apoptosis. N-Hydroxyphthalimide inhibits the phosphorylation of mTOR (Ser2448, Ser2481) and Akt (Ser473). N-Hydroxyphthalimide has anticancer effects against breast and colon cancer .

HY-W007743

Boc-Pip-OH Boc-L-pipecolic acid	Biochemical Assay Reagents
Boc-Pip-OH (Boc-L-pipecolic acid) is a t-butyloxycarbonylamino acid. Boc-Pip-OH can serve as a radical precursor .

HY-W130177

Iodocholine iodide	Biochemical Assay Reagents
Iodocholine iodide is a non-toxic, metabolizable "green" catalyst that can catalyze the free radical polymerization of functional polymers. Iodocholine iodide is also the non-radioactive iodide of Carbon-11 choline. C-11 Choline can be used in PET imaging and non-informative bone scintigraphy, CT or MRI to monitor various types of cancer .

HY-W015913R

Pyruvic acid sodium (Standard) 5+ Cited Publications Sodium 2-oxopropanoate (Standard); Acetylformic acid sodium (Standard)	Biochemical Assay Reagents
Sodium 2-oxopropanoate (Standard) is the analytical standard of Sodium 2-oxopropanoate. This product is intended for research and analytical applications. Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS .

HY-W790758

Tripropylammonium hexafluorophosphate	Biochemical Assay Reagents
Tripropylammonium hexafluorophosphate is a potent, cell-permeable free radical scavenger suitable for the detection of superoxide radicals and peroxynitrite in vitro.

HY-W616806

Sodium 6-oxo-3,6-dihydropurin-7-ide	Biochemical Assay Reagents
Sodium 6-oxo-3,6-dihydropurin-7-ide, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia.

HY-W776847

3-(2-Iodoacetamido)-proxyl	Biochemical Assay Reagents
3-(2-Iodoacetamido)-proxyl serves as a free radical spin probe employed in spin labeling techniques, which facilitate the exploration of the dynamic interactions among molecules, proteins, lipids, and cell membranes.

HY-W099538R

Dilauryl thiodipropionate (Standard)

Dilauryl 3,3'-Thiodipropionate (Standard)

Biochemical Assay Reagents

Dilauryl thiodipropionate (Standard) is the analytical standard of Dilauryl thiodipropionate. This product is intended for research and analytical applications. Dilauryl thiodipropionate (DLTDP), which is a sulfur-containing antioxidant commonly used to stabilize polymers and plastics against degradation caused by heat, oxygen, and UV light, acts to scavenge free radicals and others that may cause polymer chain scission and cross-linked active substances, in addition, DLTDP has been used as an additive to lubricants, oils and other industrial fluids to improve their oxidation stability, the long hydrocarbon chain in DLTDP makes it low volatility and compatible with many materials and Good compatibility with substrates.

HY-Y0396R

N-Hydroxyphthalimide (Standard)

Biochemical Assay Reagents

N-Hydroxyphthalimide (Standard) is the analytical standard of N-Hydroxyphthalimide (HY-Y0396). This product is intended for research and analytical applications. N-Hydroxyphthalimide is a blocking agent and catalyst. N-Hydroxyphthalimide promotes oxidation reactions by generating PINO free radicals and activating hydrogen atom transfer processes. N-Hydroxyphthalimide reduces the expression of anti-apoptotic proteins Survivin and Bcl-xL and activates caspase 9 and caspase 3. N-Hydroxyphthalimide induces Apoptosis. N-Hydroxyphthalimide inhibits the phosphorylation of mTOR (Ser2448, Ser2481) and Akt (Ser473). N-Hydroxyphthalimide has anticancer effects against breast and colon cancer .

HY-W011426R

Isopropyl palmitate (Standard)

Propan-2-yl hexadecanoate (Standard)

Biochemical Assay Reagents

Isopropyl palmitate (Standard) is the analytical standard of Isopropyl palmitate. This product is intended for research and analytical applications. Isopropyl palmitate is an fatty acid ester. Isopropyl palmitate can be used for design and characterization of bioactive bilayer films. The bilayer membrane not only has the ability to scavenge free radicals and inhibit lipid peroxidation, but also can inhibit the growth of known foodborne pathogens. Isopropyl palmitate can be used as an excipient, such as lubricant, oily carrier, solvent, controlled-release transdermal film. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .

Cat. No.	Product Name	Target	Research Area

HY-D0187

L-Glutathione reduced Maximum Cited Publications 54 Publications Verification GSH; γ-L-Glutamyl-L-cysteinyl-glycine	Endogenous Metabolite Reactive Oxygen Species (ROS) Ferroptosis	Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
L-Glutathione reduced (GSH; γ-L-Glutamyl-L-cysteinyl-glycine) is an endogenous antioxidant and is capable of scavenging oxygen-derived free radicals.

HY-W013494

L-Carnosine 2 Publications Verification	Endogenous Metabolite	Metabolic Disease Inflammation/Immunology
L-Carnosine is a dipeptide composed of beta-alanine and histidine. L-Carnosine is an endogenous metabolite found in human brain, muscle and gastrointestinal tissues and is present in all vertebrates. L-Carnosine is a non-enzymatic free radical scavenger and natural antioxidant with anti-inflammatory and neuroprotective properties that can inhibit biochemical changes associated with aging .

HY-P1934A

Cyclo(L-Phe-L-Pro)	Fungal Bacterial IFNAR Reactive Oxygen Species (ROS)	Infection Inflammation/Immunology Cancer
Cyclo(L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide . Cyclo(L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation . Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC₅₀ of 24 µM in the DPPH assay .

HY-D0187R

L-Glutathione reduced (Standard) GSH (Standard); γ-L-Glutamyl-L-cysteinyl-glycine (Standard)	Reference Standards Endogenous Metabolite Reactive Oxygen Species (ROS) Ferroptosis	Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
L-Glutathione reduced (Standard) is the analytical standard of L-Glutathione reduced. This product is intended for research and analytical applications. L-Glutathione reduced (GSH; γ-L-Glutamyl-L-cysteinyl-glycine) is an endogenous antioxidant and is capable of scavenging oxygen-derived free radicals.

HY-132828

Odatroltide LT3001; DHDMIQK(KAP)	P-selectin	Cardiovascular Disease Metabolic Disease Inflammation/Immunology
Odatroltide (LT3001; DHDMIQK(KAP)) is a P-selectin inhibitor. Odatroltide is a peptide molecule comprising a tripeptide Pro-Ala-Lys (PAK) and an (S)-6,7-dihydroxy-1,1-dimethyl-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid domain. Odatroltide can restore cerebral blood flow, scavenge free radicals, and inhibit leukocyte migration. Odatroltide possesses thrombolytic and anti-thrombotic activities .

HY-P4280

Arg-Tyr H-Arg-Tyr-OH	Reactive Oxygen Species (ROS)	Others
Arg-Tyr is a dipeptide which has strong hydroxyl-radical and hydrogen-peroxide scavenging activity .

HY-N9413

γ-Glutamyl-S-allylcysteine L-γ-Glutamyl-(S)-Allyl-Cysteine	Peptides	Metabolic Disease
γ-Glutamyl-S-allylcysteine (L-γ-Glutamyl-(S)-Allyl-Cysteine) is a naturally occurring organosulfur compound found in garlic. γ-Glutamyl-S-allylcysteine has antiglycative effect and shows radical-scavenging and metal-chelating capacities .

HY-W001158

N,N-Dimethylglycine hydrochloride 1 Publications Verification Dimethylglycine hydrochloride; DMG hydrochloride; N-Methylsarcosine hydrochloride	Endogenous Metabolite iGluR Amino Acid Derivatives	Neurological Disease Metabolic Disease
N,N-Dimethylglycine (Dimethylglycine) hydrochloride, a natural N-methylated glycine, is a nutrient supplement and acts as an NMDAR glycine site partial agonist. N,N-Dimethylglycine hydrochloride is a methyl donor that can improve immunity, act as an antioxidant to prevent oxidative stress, and scavenge excess free radicals. N,N-Dimethylglycine hydrochloride has antidepressant-like and surfactant effects .

HY-W013494R

L-Carnosine (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease Cancer
L-Carnosine (Standard) is the analytical standard of L-Carnosine. This product is intended for research and analytical applications. L-Carnosine is a dipeptide of the amino acids beta-alanine and histidine and has the potential to suppress many of the biochemical changes that accompany aging. In Vitro: L-Carnosine is a dipeptide of the amino acids beta-alanine and histidine and has the potential to suppress many of the biochemical changes that accompany aging . L-Carnosine also exhibits some antioxidant effects. The antioxidant mechanism of L-Carnosine is attributed to its chelating effect against metal ions, superoxide dismutase (SOD)-like activity, and ROS and free radicals scavenging ability .

HY-145779A

H-Glu(Met-OH)-OH TFA H-γ-Glu-Met-OH TFA; γ-Glu-Met TFA	Peptides	Metabolic Disease
H-Glu(Met-OH)-OH TFA (γ-Glu-Met TFA) could induce oxidation of hydroxyl radical .

HY-P5641

Pleurocidin 1 Publications Verification	Bacterial p38 MAPK NF-κB NADH Dehydrogenase Antibiotic	Infection Inflammation/Immunology
Pleurocidin is an Antimicrobial peptide. Pleurocidin is derived from the skin mucosa or intestinal secretions of Pseudopleuronectes americanus. Pleurocidin inhibits the expression of key proteins in the MAPK and NF-κB inflammatory signaling pathways. Pleurocidin alters serum inflammatory and immune cytokine levels, regulates the down-regulation of tight junction proteins, and modulates the intestinal flora. Pleurocidin exerts antibacterial activity by inducing bacterial membrane damage, hydroxyl radical formation, and NADH depletion, and also produces a synergistic effect with Antibiotics. Pleurocidin alleviates DSS-induced ulcerative colitis. Pleurocidin can be used for research on ulcerative colitis, bacterial infections, and bacterial biofilm-related infections .

HY-145779

H-Glu(Met-OH)-OH H-γ-Glu-Met-OH; γ-Glu-Met	Dipeptidyl Peptidase	Metabolic Disease
H-Glu(Met-OH)-OH (H-γ-Glu-Met-OH; γ-Glu-Met) is a DPP-IV inhibitor with an IC₅₀ of 2.11 mM. H-Glu(Met-OH)-OH binds to DPP-IV’s active site to block substrate binding. H-Glu(Met-OH)-OH can be used for the research of type 2 diabetes .

HY-P1512A

Antioxidant peptide A TFA	Peptides	Cancer
Antioxidant peptide A TFA is a short peptide, which contains alternative aromatic or sulfur-containing amino acid. The side chains of Antioxidant peptide A are believed to contribute to strong radical scavenging activities of peptides in the cancer cell .

HY-P1512

Antioxidant peptide A	SOD	Cancer
Antioxidant peptide A is a short peptide, which contains alternative aromatic or sulfur-containing amino acid. The side chains of Antioxidant peptide A are believed to contribute to strong radical scavenging activities of peptides in the cancer cell.

HY-P5318

MDYYFEER	Reactive Oxygen Species (ROS)	Inflammation/Immunology
MDYYFEER is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MDYYFEER has high DPPH and ABTS radical scavenging ability. MDYYFEER protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-P5317

MAQAAEYYR	Reactive Oxygen Species (ROS)	Inflammation/Immunology
MAQAAEYYR is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MAQAAEYYR has high DPPH, ABTS radical and ROS-scavenging ability. MAQAAEYYR protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-P5316A

MHLWAAK TFA	Peptides	Inflammation/Immunology
MHLWAAK TFA is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MHLWAAK TFA has high DPPH and ABTS radical scavenging ability. MHLWAAK TFA protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-P5318A

MDYYFEER TFA	Peptides	Inflammation/Immunology
MDYYFEER TFA is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MDYYFEER TFA has high DPPH and ABTS radical scavenging ability. MDYYFEER TFA protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-P5317A

MAQAAEYYR TFA	Reactive Oxygen Species (ROS)	Inflammation/Immunology
MAQAAEYYR TFA is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MAQAAEYYR TFA has high DPPH, ABTS radical and ROS-scavenging ability. MAQAAEYYR TFA protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-P1934AR

Cyclo(L-Phe-L-Pro) (Standard)	Reference Standards Fungal Bacterial IFNAR Reactive Oxygen Species (ROS)	Infection Inflammation/Immunology Cancer
Gallic acid (hydrate) (Standard) is the analytical standard of Gallic acid (hydrate). This product is intended for research and analytical applications. Cyclo(L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide . Cyclo(L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation . Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC₅₀ of 24 µM in the DPPH assay .

HY-P5316

MHLWAAK	Peptides	Inflammation/Immunology
MHLWAAK is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MHLWAAK has high DPPH and ABTS radical scavenging ability. MHLWAAK protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-P11646

Brazzein	COX	Metabolic Disease Inflammation/Immunology
Brazzein is a functional sweetener with antioxidant, anti-inflammatory, and anti-allergic activities. Brazzein inhibits COX-2 with an IC₅₀ of 12.62 μM. Brazzein exhibits strong antioxidant effects, showing ABTS radical scavenging activity (IC₅₀ = 12.55 μM) . Brazzein shows no antibacterial or antifungal activity. Brazzein can be used for the research of obesity, metabolic disorder, inflammation .

Cat. No.	Product Name	Target	Research Area	Image

HY-P99731

Milatuzumab 4 Publications Verification hLL1; MEDI-115	CD74	Cancer
Milatuzumab (hLL1; MEDI-115) is a humanized anti-CD74 monoclonal antibody. CD74, a integral membrane protein, is associated with the promotion of B-cell growth and survival. Milatuzumab causes free radical oxygen generation, and loss of mitochondrial membrane potential. Milatuzumaba also decreases CD20/CD74 aggregates and cell adhesion, to lead to cell death .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W015913

Pyruvic acid sodium 15+ Cited Publications Sodium 2-oxopropanoate; Acetylformic acid sodium	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Reactive Oxygen Species (ROS) Endogenous Metabolite
Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS .

HY-N0499

Cyanidin Chloride 4 Publications Verification IdB 1027	Structural Classification Anthocyans Flavonoids other families Classification of Application Fields Anti-aging Phenols Polyphenols Plants Disease Research Fields Source Classification Cancer	Prostaglandin Receptor
Cyanidin Chloride (IdB 1027) is an orally active antioxidant and enzyme inhibitor. Cyanidin Chloride has IC₅₀ values of 90 μM and 60 μM against PGHS-1 and PGHS-2, respectively. Cyanidin Chloride exhibits excellent antioxidant and anti-inflammatory activities, scavenges free radicals, inhibits lipid peroxidation, and protects DNA from cleavage. Cyanidin Chloride can be used in the research of inflammatory diseases .

HY-116807

Dihydrolipoic Acid 2 Publications Verification DHLA	Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Source Classification	Reactive Oxygen Species (ROS)
Dihydrolipoic Acid (DHLA) is an excellent antioxidant capable of scavenging almost any oxygen-centered radical . Dihydrolipoic acid exhibits anti-inflammatory properties in various diseases. Dihydrolipoic Acid exerts a preventive effect via ERK/Nrf2/HO-1/ROS/NLRP3 pathway in LPS-induced sickness behavior rats. Dihydrolipoic Acid can be used for the reaserch of depression .

HY-W020183

γ-Terpinene	Structural Classification Other Monoterpenes other families Terpenoids Plants Source Classification	Environmental Pollutants Fungal Bacterial
γ-Terpinene, a monoterpene, is an orally active antioxidant compound which can scavenge radicals directly. γ-Terpinene has potent antinociception activity. γ-Terpinene exhibits antimicrobial efficacy against various bacteria and fungi .

HY-N3220

Myricetin 3-O-galactoside 1 Publications Verification	Flavonols Flavonoids Rhododendron dauricum Linn. Classification of Application Fields Phenols Polyphenols Metabolic Disease Ericaceae Plants Disease Research Fields Source Classification	Xanthine Oxidase
Myricetin 3-O-galactoside inhibits xanthine oxidase (XO) activity, lipid peroxidation and scavenges the free radical. Myricetin 3-O-galactoside inhibits lipid peroxidation with an IC₅₀ of 160 μg/mL. Antioxidant activity .

HY-N0627

Kaempferol-7-O-β-D-glucopyranoside	Flavonols Structural Classification Flavonoids other families Classification of Application Fields Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields Source Classification	LDLR
Kaempferol-7-O-β-D-glucopyranoside is a flavonoid glycoside. Kaempferol-7-O-β-D-glucopyranoside exists in the root bark of Cudrania tricuspidata. Kaempferol-7-O-β-D-glucopyranoside inhibits Cu ²⁺-induced lipid peroxidation of low-density lipoprotein. Kaempferol-7-O-β-D-glucopyranoside possesses antioxidant activity and scavenges DPPH free radicals .

HY-N8220

2-(2-Phenylethyl)chromone Flidersiachromone	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Thymelaeaceae Other Diseases Plants Aquilaria sinensis (Lour.) Spreng. Disease Research Fields Source Classification	Glycosidase
2-(2-Phenylethyl) chromone (Flidersiachromone) is a chromone derivative and antioxidant. 2-(2-Phenylethyl) chromone scavenges ABTS· ⁺ free radicals, and its derivatives exhibit diverse activities including anti-inflammatory, neuroprotective, anti-tumor, and α-glucosidase inhibitory effects. 2-(2-Phenylethyl) chromone is applicable to experimental research in fields such as inflammation-related diseases, tumors, and neurodegenerative diseases .

HY-N1750

3-(2,4-Dihydroxyphenyl)propanoic acid	Structural Classification Natural Products Classification of Application Fields Plants Moraceae Endogenous metabolite Human Gut Microbiota Metabolites Ficus carica L. Other Diseases Phenols Polyphenols Disease Research Fields Source Classification	Tyrosinase
3-(2,4-Dihydroxyphenyl) propanoic acid (DPPacid) is a competitive Tyrosinase inhibitor. It exhibits an IC₅₀ value of 3.02 μM against mushroom tyrosinase with L-tyrosine as the substrate, an IC₅₀ value of 62 μM with DL-DOPA as the substrate, and a K_i value of 11.5 μM. 3-(2,4-Dihydroxyphenyl) propanoic acid shows no DPPH radical scavenging activity. It can be used in studies related to ultraviolet B (UVB)-induced hyperpigmentation .

HY-34350

2-(Aminomethyl)phenol 2-Hydroxybenzylamine; o-Hydroxybenzylamine; 2-HOBA	Cardiovascular Disease Monophenols Reseda odorata L. Oleaceae Classification of Application Fields Phenols Plants Inflammation/Immunology Disease Research Fields	Reactive Oxygen Species (ROS)
2-(Aminomethyl)phenol (2-Hydroxybenzylamine) is a selective dicarbonyl scavenger. 2-(Aminomethyl)phenol is an antioxidant and scavanger of free radicals and isolevuglandins (IsoLGs). 2-(Aminomethyl)phenol can prevent early recurrence of atrial fibrillation. 2-(Aminomethyl)phenol can reduce inflammation and plaque apoptotic cells and promote efferocytosis and features of stable plaques. 2-(Aminomethyl)phenol can reduce malondialdehyde (MDA)-LDL and MDA-HDL levels in Ldlr ^-/- mouse model. 2-(Aminomethyl)phenol can be studied in the research of inflammation and cardiovascular disease, such as atherosclerosis, early recurrence of atrial fibrillation (AF) and arrhythmias .

HY-W001542

5-Hydroxyoxindole	Alkaloids Monophenols Neurological Disease Classification of Application Fields Rubiaceae Phenols Haldina cordifolia (Roxb.) Ridsd. Metabolic Disease Plants Disease Research Fields Indole Alkaloids Source Classification	Reactive Oxygen Species (ROS)
5-Hydroxyoxindole is a structural analog of uric acid for its antioxidant. 5-Hydroxyoxindole has DPPH radical scavenging activities and lipid peroxidation-inhibitory activities. 5-Hydroxyoxindole is a product of partial metabolism of tryptophan involving conversion in the gut lumen of tryptophan to indole through the action of bacterial tryptophanase and tryptophan synthase. 5-Hydroxyoxindole is one of the main molecules responsible for the neurological symptoms of hepatic encephalopathy in rats. 5-Hydroxyoxindole can be used for the research of oxidative stress-mediated disorders .

HY-N4177

Rubrofusarin gentiobioside	Seeds of Cassia tora Linn. Monophenols other families Classification of Application Fields Leguminosae Phenols Metabolic Disease Plants Disease Research Fields Source Classification	Others
Rubrofusarin gentiobioside is isolated from the seeds of Cassia tora L. Rubrofusarin gentiobioside has a radical scavenging effect .

HY-N0499A

Cyanidin	Structural Classification Caprifoliaceae Phenols Polyphenols Sambucus williamsii Hance Plants Source Classification	Prostaglandin Receptor
Cyanidin is an orally active antioxidant and enzyme inhibitor. Cyanidin has IC₅₀ values of 90 μM and 60 μM against PGHS-1 and PGHS-2, respectively. Cyanidin exhibits excellent antioxidant and anti-inflammatory activities, scavenges free radicals, inhibits lipid peroxidation, and protects DNA from cleavage. Cyanidin can be used in the research of inflammatory diseases .

HY-N7692

Polyporusterone A	Classification of Application Fields Polyporaceae Other Diseases Poria cocos Plants Disease Research Fields Steroids Source Classification	Others
Polyporusterone A is a triterpene carboxylic acid isolated from Polyporus umbellatus Fries. Polyporusterone A has inhibitory effect on free radical-induced lysis of red blood cells (hemolysis) .

HY-N2307A

Lirinidine (+)-Lirinidine	Alkaloids Monophenols Classification of Application Fields Phenols Nelumbo nucifera Gaertn. Plants Isoquinoline Alkaloids Disease Research Fields Nymphaeaceae Cancer Source Classification	Others
Lirinidine ((+)-Lirinidine) is an alkaloid isolated from the leaves of L. tulipifera and has antioxidant and anticancer activities. Lirinidine exhibits medium ferric reducing power activity and minor radical scavenging activity in vitro. Lirinidine can be used for cosmetic research .

HY-W021267

3-Demethylcolchicine	Alkaloids Structural Classification Monophenols other families Classification of Application Fields Other Alkaloids Phenols Plants Inflammation/Immunology Disease Research Fields Source Classification	Reactive Oxygen Species (ROS)
3-Demethylcolchicine, a colchicine metabolite and anti-inflammatory agent, exhibits potent tubulin-binding activity. 3-Demethylcolchicine inhibits carrageenan-induced rat paw edema. 3-Demethylcolchicine bears a hydroxyl group on its carbocyclic ring; this group participates in free radical scavenging processes, allowing it to act as a free radical scavenger. 3-Demethylcolchicine is applicable to studies related to carrageenan-induced paw edema .

HY-N4168B

Methyl chlorogenate	Crataegus monogyna Jacq. Rosaceae Phenols Polyphenols Plants Source Classification	Others
Methyl chlorogenate is an antioxidant, and has radical scavenging activity. Methyl chlorogenate is an anti-inflammatory agent. Methyl chlorogenate also inhibits hepatocellular carcinoma (HCC) cell proliferation and metastasis .

HY-N8194

Syringetin-3-O-glucoside Syringetin 3-O-β-D-glucoside	Flavonols Flavonoids Vitis vinifera cv. Zalema Phenols Polyphenols Plants Vitaceae Source Classification	Others
Syringetin-3-O-glucosid (Syringetin 3-O-β-D-glucoside), a flavonol glycoside, shows relatively weak DPPH and ABTS radical scavenging activity .

HY-N3985

Gyrophoric acid	Microorganisms Classification of Application Fields Phenols Polyphenols Disease Research Fields Source Classification Cancer	Others
Gyrophoric acid is a good ultraviolet filter in lichen populations. Gyrophoric acid shows *DPPH radical* scavenging** activity with an IC₅₀ value of 105.75 μg/ml .

HY-N7693

Polyporusterone B 1 Publications Verification	Classification of Application Fields Polyporaceae Other Diseases Poria cocos Plants Disease Research Fields Steroids Source Classification	Others
Polyporusterone B is a triterpene carboxylic acid isolated from Polyporus umbellatus Fries. Polyporusterone B has inhibitory effect on free radical-induced lysis of red blood cells (hemolysis) .

HY-N9447

Norbergenin 1 Publications Verification	Natural Products other families Phenols Polyphenols Plants Source Classification	Reactive Oxygen Species (ROS)
Norbergenin, the O-demethyl derivative of bergenin, shows moderate antioxidant activity (IC₅₀ 13 μM in DPPH radical scavenging; 32 μM in superoxide anion scavenging) .

HY-N10917

Xanthohumol I	Structural Classification Humulus lupulus L. Phenols Polyphenols Plants Moraceae Source Classification	Drug Derivative
Xanthohumol I is a derivative of Chalcone (HY-121054) that can be isolated from Humulus lupulus L. (hops). Xanthohumol I exhibits free radical scavenging activity .

HY-N9895

3,5-Dicaffeoyl-epi-quinic acid	Dendranthema morifolium (Ramat.) Tzvel. Phenols Polyphenols Plants Compositae Source Classification	Others
3,5-Dicaffeoyl-epi-quinic acid can be extracted from Chrysanthemum morifolium. 3,5-Dicaffeoyl-epi-quinic acid has antioxidant activities. 3,5-Dicaffeoyl-epi-quinic acid can scavenge DPPH radical and superoxide anion radical, with IC₅₀s of 5.6 and 2.9 μg/mL respectively .

HY-N8219

Isoarundinin II	Bletilla striata (Thunb. ex Murray) Rchb. f. Structural Classification Classification of Application Fields Orchidaceae Other Diseases Phenols Polyphenols Plants Disease Research Fields Source Classification	Reactive Oxygen Species (ROS)
Isoarundinin II is a bibenzyl compound found in the pseudobulbs of Pleione grandiflora (Rolfe) Rolfe. Isoarundinin II scavenges DPPH free radicals .

HY-111523

Isomahanine	Alkaloids Rutaceae Murraya koenigii (L.) Spreng Plants Indole Alkaloids	p38 MAPK Apoptosis Autophagy Caspase
Isomahanine, carbazole alkaloid, is an antioxidative agent. Isomahanine has DPPH radical scavenging activity with an IC₅₀ value of 24 μM .

HY-N3596

Cleomiscosin C Aquillochin	Thymelaeaceae Phenols Polyphenols Plants Aquilaria sinensis (Lour.) Spreng. Source Classification	Others
Cleomiscosin C (Aquillochin) can be isolated from Aquilaria agallocha. Cleomiscosin C has antioxidant activity. Cleomiscosin C inhibits LDL oxidation and free radicals generation .

HY-N8042

Erigeside I	Ulex europaeus L. Phenols Polyphenols Plants Compositae Saccharides Monosaccharides Source Classification	Others
Erigeside I is a free radical scavenger isolated from Erigeron breviscapus .

HY-N10176

D-Isofloridoside	Cardiovascular Disease other families Classification of Application Fields Plants Disease Research Fields Saccharides Source Classification	Reactive Oxygen Species (ROS) MMP
D-Isofloridoside, one of the polysaccharide precursors, has the activity of scavenging free radicals, inhibiting ROS expression, and inhibiting MMP-2 and MMP-9 .

HY-W002773

Methyl isovanillate	Monophenols other families Classification of Application Fields Other Diseases Phenols Plants Disease Research Fields Source Classification	Endogenous Metabolite
Methyl isovanillate is a secondary metabolite isolated from Vitex agnus-castus. Methyl isovanillate does not exhibit significant activity in the DPPH free radical* scavenging experiment* .

HY-N15684

Rhodoxanthin	Natural Products Animals Source Classification	Others
Rhodoxanthin is a carotenoid. Rhodoxanthin exerts antioxidant activity via free radical scavenging and lipid peroxidation inhibition. Rhodoxanthin is promising for research of oxidative stress-related diseases (e.g., UV-induced skin damage) .

HY-N16658

Asperilin NSC 85238	Structural Classification Terpenoids Sesquiterpenes Plants Compositae Oparanthus teikiteetinii (J.Florence & Stuessy) R.K.Shannon & W.L.Wagner Source Classification	Glutathione Peroxidase
Asperilin (NSC 85238) is an orally active sesquiterpene lactone. Asperilin is an effective hydroxyl radical scavenger. Asperilin significantly enhance the lipid peroxidation levels of liver microsomes in various systems. Asperilin leads to a significant decrease in liver glutathione (GSH) levels and an increase in glutathione peroxidase (GPx) activity. Asperilin can be used for research on inflammatory conditions .

HY-116866

Sclerotiorin	Structural Classification Natural Products Microorganisms Source Classification	Lipoxygenase Fungal
Sclerotiorin is a reversible and uncompetitive inhibitor against soybean lipoxygenase-1 (LOX-1) (IC₅₀: 4.2 μM). Sclerotiorin also shows antioxidant activity by scavenging free radical (ED₅₀: 0.12 μM), and nonenzymatic lipid peroxidation inhibition activity. Sclerotiorin has antifungal activity, and also inhibits platelet aggregation. Sclerotiorin can be purified from the fermented broth of Penicillium frequentans .

HY-W001542R

5-Hydroxyoxindole (Standard)	Alkaloids Structural Classification Monophenols Rubiaceae Phenols Haldina cordifolia (Roxb.) Ridsd. Plants Indole Alkaloids Source Classification	Reference Standards Reactive Oxygen Species (ROS)
5-Hydroxyoxindole is a structural analog of uric acid for its antioxidant. 5-Hydroxyoxindole has DPPH radical scavenging activities and lipid peroxidation-inhibitory activities. 5-Hydroxyoxindole is a product of partial metabolism of tryptophan involving conversion in the gut lumen of tryptophan to indole through the action of bacterial tryptophanase and tryptophan synthase. 5-Hydroxyoxindole is one of the main molecules responsible for the neurological symptoms of hepatic encephalopathy in rats. 5-Hydroxyoxindole can be used for the research of oxidative stress-mediated disorders .

HY-N11845

Sigmoidin B	Flavonoids Flavones Leguminosae Plants Erythrina latissima E. Mey. Source Classification	Lipoxygenase
Sigmoidin B, a prenylated flavanone, is a selective 5-lipoxygenase inhibitor. Sigmoidin B is a potent scavenger of the DPPH radical. Sigmoidin B has antigenotoxic activity that inhibits genotoxicity induced by Aflatoxin B1 (HY-N6615), with an IC₅₀ of 18.7 μg/mL. Sigmoidin B has anti-inflammatory activity and antioxidant properties .

HY-N8955

Maritimein	Structural Classification Amburana cearensis (Allemão) A.C.Sm. Plants Compositae Saccharides Monosaccharides Source Classification	Reactive Oxygen Species (ROS)
Maritimein is an aurone glucoside and antioxidant with free radical scavenger activity, found in Coreopsis tinctoria Nutt.Maritimein scavenges ABTS•+ radical cations .

HY-N15703

Norisocorydine (+)-Norisocorydine	Alkaloids Microorganisms Unonopsis stipitata Diels Plants Annonaceae Isoquinoline Alkaloids Source Classification	Others
Norisocorydine ((+)-Norisocorydine) is an aporphine alkaloid with antinociceptive and radical scavenging effects. Norisocorydine shows a SC₅₀ of 14.1 μg/mL in DPPH radical scavenging test. Norisocorydine exhibits antinociceptive ability in mice .

HY-N16406

Auroglaucin	Microorganisms Phenols Polyphenols Source Classification	SOD
Auroglaucin is a potent antioxidant. Auroglaucin shows 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging capacity and superoxide radical scavenging activity with EC₅₀ value of 74.6, 12.3 µM, respectively. Auroglaucin shows low activity for inhibiting the autoxidation of docosahexaenoic acid (DHA) .

HY-N10020

Patulitrin	Flavonols Flavonoids Ohwia caudata (Thunberg) H. Ohashi Plants Compositae Source Classification	Lipoxygenase
Patulitrin has scavenging effect in the DPPH radical. Patulitrin inhibits soybean lipoxygenase. Patulitrin also has antihypertensive effect. Patulitrin is an antioxidant flavonoid that can be isolated from Anthemis tinctoria .

HY-N15440

Mutatochrome Citroxanthin	Natural Products Rosaceae Plants Rosa foetida Herrm. Source Classification	Reactive Oxygen Species (ROS) Endogenous Metabolite
Mutatochrome (Citroxanthin) is a naturally occurring carotenoid pigment found in certain plants. Mutatochrome has antioxidant property to help protect cells from damage caused by free radicals. Mutatochrome can be used for anti-inflammatory and anticancer study .

HY-W015913R

Pyruvic acid sodium (Standard) 5+ Cited Publications Sodium 2-oxopropanoate (Standard); Acetylformic acid sodium (Standard)	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Reactive Oxygen Species (ROS) Endogenous Metabolite
Sodium 2-oxopropanoate (Standard) is the analytical standard of Sodium 2-oxopropanoate. This product is intended for research and analytical applications. Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS .

HY-N3554

Catechin-7-O-β-D-xylopyranoside (+)-Catechol 7-β-D-xylopyranoside	Betula pendula Roth. Plants Saccharides Betulaceae Monosaccharides Source Classification	Others
Catechin-7-O-β-D-xylopyranoside is an antioxidant compound with strong DPPH free radical scavenging ability. Catechin-7-O-β-D-xylopyranoside can be extracted from birch inner bark and nepeta stem bark .

HY-N9095

Curculigoside C	Curculigo orchioides Gaertn. Phenols Polyphenols Plants Amaryllidaceae Source Classification	Others
Curculigoside C is a phenolic glucoside with potent antioxidative and neuroprotective activities. Curculigoside C shows IC₅₀ values of 0.25 mM and 0.88 mM for hydroxyl radicals and superoxide anion radicals, respectively .

HY-N8579

Eugenyl benzoate	Microorganisms Simple Phenylpropanols Phenylpropanoids Source Classification	Others
Eugenyl benzoate has the potency for scavenging of DPPH radical. Eugenyl Benzoate Derivatives can be used for development of BCL-2 inhibitors .

HY-N9953

Chrysophanol 8-O-β-D-(6′-O-galloyl)glucopyranoside	Quinones Anthraquinones Polygonaceae Rheum rhabarbarum Linnaeus Plants Source Classification	Others
Chrysophanol 8-O-β-D-(6’-O-galloyl)glucopyranoside, an anthraquinone glucoside, can be isolated from Rheum undulatum L. Chrysophanol 8-O-β-D-(6’-O-galloyl)glucopyranoside has potent DPPH radical and ?O₂ ^- scavenging activity .

HY-N9068

Alterlactone	Natural Products Microorganisms Source Classification	Fungal
Alterlactone is an antimicrobial. Alterlactone shows broad antimicrobial activity against bacterial and fungal. Alterlactone has strong radical scavenging activity .

HY-N7518

Eulophiol	Structural Classification Classification of Application Fields Pholidota yunnanensis Rolfe Orchidaceae Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields Source Classification	MMP
Eulophiol shows the 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity with an EC₅₀ of 27.7μM. Antioxidant activity .

HY-N1859

3'-O-Methylorobol	Flavonoids Alhagi maurorum var. sparsifolium (Shap.) Yakovlev/Alhagi sparsifolia Shap. Classification of Application Fields Leguminosae Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields Isoflavones Source Classification	Others
3'-O-Methylorobol, an antioxidant flavonoid, exhibits moderate antioxidant activity in the 2,2-diphenyl-1-picrylhydrazyl free radical scavenging assay .

HY-114651

Phenazoviridin	Microorganisms Saccharides Monosaccharides Source Classification	Others
Phenazoviridin is a free radical scavenger. Phenazoviridin shows strong inhibitory activity against lipid peroxidation in rat brain homogenate and exhibits antihypoxic activity in mice .

HY-N10770

5'-Geranyl-5,7,2',4'-tetrahydroxyflavone	Flavonoids Gramineae Plants Other Flavonoids Saccharum officinarum Source Classification	Others
5'-Geranyl-5,7,2',4'-tetrahydroxyflavone, a phenolic compound, presents strong oxygen radical absorbance capacity (ORAC), DPPH radical-scavenging capacity, ABTS radical-scavenging capacity, ferric reducing antioxidant power (FRAP) and nitrite-scavenging capacity. 5'-Geranyl-5,7,2',4'-tetrahydroxyflavone has the potential for natural antioxidant research .

HY-N9051

6-Prenylquercetin-3-Me ether	Flavonoids Flavones Leguminosae Plants Glycyrrhiza uralensis Fisch. Source Classification	Glycosidase
6-Prenylquercetin-3-Me ether is a natural product that can be extracted from G. uralensis leaves. 6-Prenylquercetin-3-Me ether has radical scavenging activity toward DPPH. 6-Prenylquercetin-3-Me ether also has inhibitory activity against α-glucosidase .

HY-125568

Pyridoxatin	Alkaloids Microorganisms Classification of Application Fields Other Diseases Pyridine Alkaloids Disease Research Fields Source Classification	MMP
Pyridoxatin is a free radical scavenger of microbial origin. Pyridoxatin is isolated from a fungus culture identified as Acremonium sp. BX86. Pyridoxatin inhibits lipid peroxidation induced by free radicals in rat liver microsomes free from vitamin E .

Cat. No.	Product Name	Chemical Structure

HY-D0187S

L-Glutathione reduced-13C2,15N
L-Glutathione reduced- ¹³C₂, ¹⁵N is the ¹³C- and ¹⁵N-labeled L-Glutathione reduced. L-Glutathione reduced (GSH) is an endogenous antioxidant and is capable of scavenging oxygen-derived free radicals.

HY-W015913S

Pyruvic acid-13C3 sodium 1 Publications Verification
Sodium 2-oxopropanoate- ¹³C₃ is the ¹³C-labeled Sodium 2-oxopropanoate. Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS .

HY-W001158S

N,N-Dimethylglycine-d6 hydrochloride

N,N-Dimethylglycine-d₆ (Dimethylglycine-d₆) hydrochloride is the deuterium labeled N,N-Dimethylglycine hydrochloride (HY-W001158). N,N-Dimethylglycine (Dimethylglycine) hydrochloride, a natural N-methylated glycine, is a nutrient supplement and acts as an NMDAR glycine site partial agonist. N,N-Dimethylglycine hydrochloride is a methyl donor that can improve immunity, act as an antioxidant to prevent oxidative stress, and scavenge excess free radicals. N,N-Dimethylglycine hydrochloride has antidepressant-like and surfactant effects .

HY-B2130S1

Uric acid-15N2
Uric acid- ¹⁵N₂ is the ¹⁵N labeled Uric acid . Uric acid, scavenger of oxygen radical, is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uric acid can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation .

HY-W654342

Spermine-d20
Spermine-d₂₀ (NSC 268508-d₂₀) is deuterium labeled Spermine. Spermine (NSC 268508) functions directly as a free radical scabenger to protect DNA from free radical attack. Spermine has antiviral effects .

HY-N0091S5

Hypoxanthine-d4
Hypoxanthine-d₄ is the deuterium labeled Hypoxanthine . Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia .

HY-W015913S3

Pyruvic acid-13C-1 sodium
Sodium 2-oxopropanoate- ¹³C is the ¹³C labeled Sodium 2-oxopropanoate . Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS .

HY-N0523S

Gallic acid-d2
Gallic acid-d₂ is the deuterium labeled Gallic acid . Gallic acid (3,4,5-Trihydroxybenzoic acid) is a natural polyhydroxyphenolic compound and an free radical scavenger to inhibit cyclooxygenase-2 (COX-2) . Gallic acid has various activities, such as antimicrobial, antioxidant, antimicrobial, anti-inflammatory, and anticance activities .

HY-W014423S2

L-Histidine-13C6 hydrochloride hydrate

L-Histidine- ¹³C₆ (hydrochloride hydrate) is the ¹³C-labeled L-Histidine hydrochloride hydrate (HY-W014423). L-Histidine hydrochloride hydrate is an endogenous metabolite. L-Histidine hydrochloride hydrate scavenges hydroxyl radicals and singlet oxygen, regulate the absorption of zinc, copper and iron, exhibits anti-inflammatory and antioxidant activities. L-Histidine hydrochloride hydrate is blood brain barrier penetrable .

HY-B2130S

Uric acid-13C,15N3
Uric acid- ¹³C, ¹⁵N₃ is the ¹³C-labeled and ¹⁵N-labeled Uric acid. Uric acid, scavenger of oxygen radical, is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uric acid can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation .

HY-N0091S6

Hypoxanthine-d2 1 Publications Verification
Hypoxanthine-d₂ is the deuterium labeled Hypoxanthine . Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia .

HY-N0091S7

Hypoxanthine-15N4 2 Publications Verification
Hypoxanthine- ¹⁵N₄ is the ¹⁵N labeled Hypoxanthine . Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia .

HY-W745029A

L-Glutathione reduced-d5 ammonium
L-Glutathione reduced-d₅ (GSH-d₅) ammonium is the deuterium labeled L-Glutathione reduced (HY-D0187). L-Glutathione reduced (GSH) is an endogenous antioxidant and is capable of scavenging oxygen-derived free radicals.

HY-W014423S3

L-Histidine-13C6,15N3 hydrochloride hydrate

L-Histidine- ¹³C₆, ¹⁵N₃ hydrochloride hydrate is the ¹³C- and ¹⁵N-labeled L-Histidine hydrochloride hydrate (HY-W014423). L-Histidine hydrochloride hydrate is an endogenous metabolite. L-Histidine hydrochloride hydrate scavenges hydroxyl radicals and singlet oxygen, regulate the absorption of zinc, copper and iron, exhibits anti-inflammatory and antioxidant activities. L-Histidine hydrochloride hydrate is blood brain barrier penetrable .

HY-N0091S2

Hypoxanthine-13C5
Hypoxanthine- ¹³C₅ is a ¹³C-labeled Hypoxanthine (HY-N0091). Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia.

HY-D0187S4

L-Glutathione reduced-13C
L-Glutathione reduced- ¹³C (GSH- ¹³C; γ-L-Glutamyl-L-cysteinyl-glycine- ¹³C) is ¹³C-labeled L-Glutathione reduced (HY-D0187). L-Glutathione reduced is an endogenous antioxidant and oxygen free radical scavenger.

HY-W014423S4

L-Histidine-d5 hydrochloride hydrate

L-Histidine-d₅ hydrochloride hydrate is the deuterium labeled L-Histidine hydrochloride hydrate (HY-W014423). L-Histidine hydrochloride hydrate is an endogenous metabolite. L-Histidine hydrochloride hydrate scavenges hydroxyl radicals and singlet oxygen, regulate the absorption of zinc, copper and iron, exhibits anti-inflammatory and antioxidant activities. L-Histidine hydrochloride hydrate is blood brain barrier penetrable .

HY-W014423S6

L-Histidine-15N hydrochloride hydrate

L-Histidine- ¹⁵N hydrochloride hydrate is the ¹⁵N-labeled L-Histidine hydrochloride hydrate (HY-W014423). L-Histidine hydrochloride hydrate is an endogenous metabolite. L-Histidine hydrochloride hydrate scavenges hydroxyl radicals and singlet oxygen, regulate the absorption of zinc, copper and iron, exhibits anti-inflammatory and antioxidant activities. L-Histidine hydrochloride hydrate is blood brain barrier penetrable .

HY-W014423S

L-Histidine-13C hydrochloride hydrate

L-Histidine- ¹³C hydrochloride hydrate is the ¹³C-labeled L-Histidine hydrochloride hydrate (HY-W014423). L-Histidine hydrochloride hydrate is an endogenous metabolite. L-Histidine hydrochloride hydrate scavenges hydroxyl radicals and singlet oxygen, regulate the absorption of zinc, copper and iron, exhibits anti-inflammatory and antioxidant activities. L-Histidine hydrochloride hydrate is blood brain barrier penetrable .

HY-B1899S

Taurodeoxycholic acid-d5

Taurodeoxycholic acid-d₅ is the deuterium labeled Taurodeoxycholic acid (HY-B1899) . Taurodeoxycholic acid, a bile acid, stabilizes the mitochondrial membrane, decreases free radical formation. Taurodeoxycholic acid inhibits apoptosis by blocking a calcium-mediated apoptotic pathway as well as caspase-12 activation. Taurodeoxycholic acid exhibits neuroprotective effect in 3-nitropropionic acid induced mouse model or genetic mouse model of Huntington's disease (HD) .

HY-113121S

Vanillylmandelic acid-d3
Vanillylmandelic acid-d₃ is the deuterium labeled Vanillylmandelic acid. Vanillylmandelic acid is the endproduct of epinephrine and norepinephrine metabolism. Vanillylmandelic acid can be used as an indication of the disorder in neurotransmitter metabolism as well. Vanillylmandelic acid has antioxidant activity towards DPPH radical with an IC₅₀ value of 33 μM .

HY-W001187S

Tempo-d18
Tempo-d₁₈ is the deuterium labeled Tempo . Tempo is a classic nitroxide radical and is a selective scavenger of ROS that dismutases superoxide in the catalytic cycle. Tempo induces DNA-strand breakage. Tempo can be used as an organocatalyst for the oxidation of primary alcohols to aldehydes. Tempo has mutagenic and antioxidant effects .

HY-W745029

L-Glutathione reduced-d5
L-Glutathione reduced-d₅ (GSH-d₅; γ-L-Glutamyl-L-cysteinyl-glycine-d₅) is the deuterium labeled L-Glutathione reduced (HY-D0187). L-Glutathione reduced (GSH; γ-L-Glutamyl-L-cysteinyl-glycine) is an endogenous antioxidant and is capable of scavenging oxygen-derived free radicals.

HY-N0683S6

α-Vitamin E-d11
α-Vitamin E-d11 ((+)-α-Tocopherol-d11) is the deuterium labeled α-Vitamin E (HY-N0683). α-Vitamin E ((+)-α-Tocopherol), a naturally occurring vitamin E form, is a potent antioxidant .

HY-42682S1

D(+)-Galactosamine-13C hydrochloride
D(+)-Galactosamine- ¹³C (hydrochloride) is the ¹³C labeled D(+)-Galactosamine hydrochloride. D(+)-Galactosamine (D-Galactosamine) hydrochloride, which is an established experimental toxin, primarily causes liver injury by the generation of free radicals and

HY-B0099S

Edaravone-d5
Edaravone-d₅ is a deuterium labeled Edaravone. Edaravone is a strong novel free radical scavenger, and inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator .

HY-N0136S

Taxifolin-d3
Taxifolin-d₃ is deuterium labeled Taxifolin. Taxifolin ((+)-Dihydroquercetin) exhibits important anti-tyrosinase activity. Taxifolin exhibits significant inhibitory activity against collagenase with an IC₅₀ value of 193.3 μM . Taxifolin is an important natural compound with antifibrotic activity. Taxifolin is a free radical scavenger with antioxidant capacity .

HY-W014423S7

L-Histidine-d3 hydrochloride hydrate

L-Histidine-d₃ hydrochloride hydrate is the deuterium labeled L-Histidine hydrochloride hydrate (HY-W014423). L-Histidine hydrochloride hydrate is an endogenous metabolite. L-Histidine hydrochloride hydrate scavenges hydroxyl radicals and singlet oxygen, regulate the absorption of zinc, copper and iron, exhibits anti-inflammatory and antioxidant activities. L-Histidine hydrochloride hydrate is blood brain barrier penetrable .

HY-W002004S1

4-Amino-TEMPO-d17

4-Amino-TEMPO-d₁₇ (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl-d₁₇) is the deuterium labeled 4-Amino-TEMPO (HY-W002004). 4-Amino-TEMPO (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl) is a stable nitroxide radical and N-nucleophile based on TEMPO. 4-Amino-TEMPO has superoxide dismutase-mimetic activity, can protect cells from oxidative damage, and has radioprotective effects. 4-Amino-TEMPO is widely used in fields such as biomedicine, materials science, and industrial production. 4-Amino-TEMPO can be used as a spin label to detect free radicals, an oxidation catalyst in industrial production, and an antioxidant stabilizer for polymers, among others .

HY-W014423S1

L-Histidine-13C6,15N3,d5 hydrochloride hydrate

L-Histidine- ¹³C₆, ¹⁵N₃,d₅ hydrochloride hydrate is the deuterium, ¹³C-, and 15-labeled L-Histidine hydrochloride hydrate (HY-W014423). L-Histidine hydrochloride hydrate is an endogenous metabolite. L-Histidine hydrochloride hydrate scavenges hydroxyl radicals and singlet oxygen, regulate the absorption of zinc, copper and iron, exhibits anti-inflammatory and antioxidant activities. L-Histidine hydrochloride hydrate is blood brain barrier penetrable .

HY-34439S1

2,5-Dimethylpyrazine-d3
2,5-Dimethylpyrazine-d₃ is deuterated labeled 2,5-Dimethylpyrazine (HY-34439). 2,5-Dimethylpyrazine is an endogenous metabolite.

HY-N0091S3

Hypoxanthine-13C2,15N
Hypoxanthine- ¹³C₂, ¹⁵N is a ¹⁵N-labeled and ¹³C-labled Hypoxanthine (HY-N0091). Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia.

HY-N0091S1

Hypoxanthine-13C,15N2
Hypoxanthine- ¹³C, ¹⁵N₂ is a ¹⁵N-labeled and ¹³C-labled Hypoxanthine (HY-N0091). Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia.

HY-N0091S

Hypoxanthine-13C5,15N4
Hypoxanthine- ¹³C₅, ¹⁵N4 is a ¹⁵N-labeled and ¹³C-labled Hypoxanthine (HY-N0091). Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia.

HY-B1978S

Iprodione-d5
Iprodione-d₅ is the deuterium labeled Iprodione . Iprodione, a dicarboximide fungicide, has a highly specific action, with a capacity to cause oxidative damage through production of free oxygen radicals (ROS). Iprodione does not appear to be species selective .

HY-N0091S4

Hypoxanthine-13C2,15N-1
Hypoxanthine- ¹³C₂, ¹⁵N-1 is a ¹⁵N-labeled and ¹³C-labled Hypoxanthine (HY-N0091). Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia.

HY-W015913S1

Pyruvic acid-d3 sodium
Sodium 2-oxopropanoate-d₃ is the deuterium labeled Sodium 2-oxopropanoate . Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS .

HY-W015913S4

Pyruvic acid-13C2-1 sodium
2-Oxopropanoate- ¹³C₂ (sodium) is the ¹³C labeled Sodium 2-oxopropanoate . Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS .

HY-W013677S

4-Fluorobenzoic acid-13C6
4-Fluorobenzoic acid- ¹³C₆ is the ¹³C₆ labeled 4-Fluorobenzoic acid (HY-W013677). 4-Fluorobenzoic acid is a drug intermediate that can be used to synthesize a series of hydrazone derivatives with antituberculosis activity and Schiff bases with DPPH radical scavenging activity.

HY-D0187S6

L-Glutathione reduced-15N
L-Glutathione reduced- ¹⁵N (GSH- ¹⁵N; γ-L-Glutamyl-L-cysteinyl-glycine- ¹⁵N) is ¹⁵N-labeled L-Glutathione reduced (HY-D0187). L-Glutathione reduced (GSH; γ-L-Glutamyl-L-cysteinyl-glycine) is an endogenous antioxidant that scavenges oxygen free radicals.

HY-W780166

Uric acid-13C
Uric acid- ¹³C is the ¹³C-labeled Uric acid (HY-B2130). Uric acid, scavenger of oxygen radical, is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uric acid can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation .

HY-W003972S1

2,6-Dimethoxyphenol-d6
2,6-Dimethoxyphenol-d₆ (Syringol-d₆) is deuterated labeled 2,6-Dimethoxyphenol (HY-W003972). 2,6-Dimethoxyphenol is a phenolic compound that scavenges free radicals and exhibits antioxidant activity. 2,6-Dimethoxyphenol is the substrate for determining laccase activity .

HY-W003972S

2,6-Dimethoxyphenol-d3
2,6-Dimethoxyphenol-d₃ (Syringol-d₃) is the deuterium labeled 2,6-Dimethoxyphenol (HY-W003972) . 2,6-Dimethoxyphenol is a phenolic compound that scavenges free radicals and exhibits antioxidant activity. 2,6-Dimethoxyphenol is the substrate for determining laccase activity .

HY-W014423S5

L-Histidine-15N3 hydrochloride hydrate

L-Histidine- ¹⁵N₃ hydrochloride hydrate is the ¹⁵N-labeled L-Histidine hydrochloride hydrate (HY-W014423). L-Histidine hydrochloride hydrate is an endogenous metabolite. L-Histidine hydrochloride hydrate scavenges hydroxyl radicals and singlet oxygen, regulate the absorption of zinc, copper and iron, exhibits anti-inflammatory and antioxidant activities. L-Histidine hydrochloride hydrate is blood brain barrier penetrable .

HY-W020183S

γ-Terpinene-d3
γ-Terpinene-d₃ is deuterated labeled γ-Terpinene (HY-W020183). γ-Terpinene, a monoterpene, is an orally active antioxidant compound which can scavenge radicals directly. γ-Terpinene has potent antinociception activity. γ-Terpinene exhibits antimicrobial efficacy against various bacteria and fungi .

HY-B0817S

Pyridaben-d13

Pyridaben-d₁₃ is the deuterium labeled Pyridaben . Pyridaben is a mitochondrial electron transport inhibitor (METI) acaricide that promotes the formation of damaging oxygen and nitrogen radicals. Pyridaben selectively inhibits complex I (NADH dehydrogenase) with an IC₅₀ value of 2.4 nM (assay sites: rat liver and bovine heart mitochondria). Pyridaben also significantly inhibits rat mitochondrial mtNOS function .

HY-W014423S8

L-Histidine-15N3,d5 hydrochloride hydrate

L-Histidine- ¹⁵N₃,d₅ hydrochloride hydrate is the deuterium and ¹⁵N labeled L-Histidine hydrochloride hydrate (HY-W014423). L-Histidine hydrochloride hydrate is an endogenous metabolite. L-Histidine hydrochloride hydrate scavenges hydroxyl radicals and singlet oxygen, regulate the absorption of zinc, copper and iron, exhibits anti-inflammatory and antioxidant activities. L-Histidine hydrochloride hydrate is blood brain barrier penetrable .

HY-W002004S

4-Amino-TEMPO-d17,15N

4-Amino-TEMPO-d₁₇, ¹⁵N (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl-d₁₇, ¹⁵N) is the deuterium labeled 4-Amino-TEMPO-d₁₇ (HY-W002004S1). 4-Amino-TEMPO (4-Amino-2,2,6,6-tetramethylpiperidine-1-oxyl) is a stable nitroxide radical and N-nucleophile based on TEMPO. 4-Amino-TEMPO has superoxide dismutase-mimetic activity, can protect cells from oxidative damage, and has radioprotective effects. 4-Amino-TEMPO is widely used in fields such as biomedicine, materials science, and industrial production. 4-Amino-TEMPO can be used as a spin label to detect free radicals, an oxidation catalyst in industrial production, and an antioxidant stabilizer for polymers, among others .

HY-N0136S1

(±)-Taxifolin-13C3

(±)-Taxifolin-13C3 ((±)-Dihydroquercetin-13C3) is a derivative of (±)-Taxifolin, labeled with 13C3. (±)-Taxifolin is the racemate of Taxifolin. Taxifolin exhibits important anti-tyrosinase activity. Taxifolin exhibits significant inhibitory activity against collagenase with an IC₅₀ value of 193.3 μM . Taxifolin is an important natural compound with antifibrotic activity. Taxifolin is a free radical scavenger with antioxidant capacity .

HY-W758421

Diquat-d8 dibromide

Diquat-d₈ dibromide is a deuterium labeled Diquat dibromide (HY-122984). Diquat dibromide is a comprehensive herbicide. Diquat dibromide increases the production of ROS and triggers mitochondrial Autophagy. Diquat dibromide generates free radicals such as superoxide anions through redox cycles, which induce oxidative stress. Diquat dibromide is cytotoxic, reproductive, and neurotoxic. Diquat dibromide is used in cotton, soybean, and other crops to combat noxious weeds .

Cat. No.	Product Name		Classification

HY-131036

MAO-IN-M30 dihydrochloride		Alkynes
MAO-IN-M30 dihydrochloride is an orally active, brain-permeable, and brain selective irreversible MAO-A (IC₅₀=37 nM) and MAO-B (IC₅₀=57 nM) inhibitor. MAO-IN-M30 dihydrochloride is a potent iron chelator and radical scavenger. MAO-IN-M30 dihydrochloride has a neuroprotective effect against Dexamethasone-induced brain cell apoptosis. MAO-IN-M30 dihydrochloride also exhibits neurorestorative activity in post MPTP and lactacystin models of Parkinson's disease . MAO-IN-M30 (dihydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-131803

3'-Azido-3'-deoxyguanosine		Azide
Urolignoside is an antioxidant with free radical scavenging activity. Urolignoside potently scavenges DPPH radical, and exhibits antioxidant to β-carotene-lineoleate model . 3'-Azido-3'-deoxyguanosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-175524

BChE/MAO-B-IN-2		Alkynes
BChE/MAO-B-IN-2 is a dual inhibitor of BChE (IC₅₀ = 0.05 μM, K_i = 0.01 μM) and MAO-B (IC₅₀ = 0.45 μM, K_i = 0.08 μM) with good blood-brain barrier permeability. BChE/MAO-B-IN-2 exhibits antioxidant activity, including DPPH radical scavenging, CUPRAC copper ion reduction, and superoxide anion scavenging. BChE/MAO-B-IN-2 can be used for the study of Alzheimer's disease (AD) .

Cat. No.	Product Name		Classification

HY-Y0320

Dimethyl sulfoxide, meets analytical specification of Ch.P. Maximum Cited Publications 346 Publications Verification DMSO, meets analytical specification of Ch.P.		Solvents
Dimethyl sulfoxide (DMSO), meets analytical specification of Ch.P. is an aprotic solvent that dissolves polar and non-polar compounds, including water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and can rapidly penetrate or enhance the penetration of other substances into biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity. Dimethyl sulfoxide also exhibits antifreeze and antibacterial properties . MCE provides Dimethyl sulfoxide that complies with the inspection standards (Ch.P) of Part 4 of the Chinese Pharmacopoeia (2020 Edition). Amicrobic, low endotoxin, can be used in various biochemical experiments such as drug dissolution.

HY-108749

Olive oil 5+ Cited Publications Cropure OL		Solvents
Olive oil (Cropure OL) is an oleaginous compound found in the fruit of the Olea europaea tree . Olive oil contains many phenolic components and exerts antioxidant activity. Olive oil exhibits hydroxyl radical scavenging, platelet aggregation inhibition and xanthine oxidase inhibitory activity. Olive oil can promote wound healing and relieve inflammation. Olive oil can be used for the research of inflammation, cancer, metabolic and cardiovascular disease, such as diabetic foot ulcers and inflammatory bowel disease .

HY-W011426

Isopropyl palmitate Propan-2-yl hexadecanoate		Solvents
Isopropyl palmitate is an fatty acid ester. Isopropyl palmitate can be used for design and characterization of bioactive bilayer films. The bilayer membrane not only has the ability to scavenge free radicals and inhibit lipid peroxidation, but also can inhibit the growth of known foodborne pathogens. Isopropyl palmitate can be used as an excipient, such as lubricant, oily carrier, solvent, controlled-release transdermal film. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .

HY-N0523A

Gallic acid hydrate 15+ Cited Publications 3,4,5-Trihydroxybenzoic acid hydrate		Antioxidants Chelating Agents Preservatives
Gallic acid (3,4,5-Trihydroxybenzoic acid) hydrate is a natural polyhydroxyphenolic compound and an free radical scavenger to inhibit cyclooxygenase-2 (COX-2) . Gallic acid hydrate has various activities, such as antimicrobial, antioxidant, antimicrobial, anti-inflammatory, and anticance activities .

HY-174569

Human NFKB1 mRNA		mRNA
Human NFKB1 mRNA encodes the human nuclear factor kappa B subunit 1 (NFKB1) protein, a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. NFKB is a critical regulator of the immediate-early response to viral infection.

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