XIE18-6
Based on 1 Customer Validation
XIE18-6 is a potent INK4C (p18) inhibitor. XIE18-6 shows potent bioactivity in hematopoietic stem cells (HSCs) expansion with an ED50 of 105.5 nM.
For research use only. We do not sell to patients.
- Purity: 98.98%
- CAS No.: 1286862-52-9
- Formula: C18H15NO6S
- Molecular Weight:373.38
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Chemical Information
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CAS No. 1286862-52-9
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Appearance Solid
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Molecular Weight 373.38
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Formula C18H15NO6S
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Color White to off-white
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SMILES
O=S(C1=CC=C(NC(C)=O)C=C1)(OC2=CC=C(C(O3)=C2)C(C)=CC3=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (133.91 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6782 mL | 13.3912 mL | 26.7824 mL | 66.9559 mL |
| 5 mM | 0.5356 mL | 2.6782 mL | 5.3565 mL | 13.3912 mL | |
| 10 mM | 0.2678 mL | 1.3391 mL | 2.6782 mL | 6.6956 mL | |
| 15 mM | 0.1785 mL | 0.8927 mL | 1.7855 mL | 4.4637 mL | |
| 20 mM | 0.1339 mL | 0.6696 mL | 1.3391 mL | 3.3478 mL | |
| 25 mM | 0.1071 mL | 0.5356 mL | 1.0713 mL | 2.6782 mL | |
| 30 mM | 0.0893 mL | 0.4464 mL | 0.8927 mL | 2.2319 mL | |
| 40 mM | 0.0670 mL | 0.3348 mL | 0.6696 mL | 1.6739 mL | |
| 50 mM | 0.0536 mL | 0.2678 mL | 0.5356 mL | 1.3391 mL | |
| 60 mM | 0.0446 mL | 0.2232 mL | 0.4464 mL | 1.1159 mL | |
| 80 mM | 0.0335 mL | 0.1674 mL | 0.3348 mL | 0.8369 mL | |
| 100 mM | 0.0268 mL | 0.1339 mL | 0.2678 mL | 0.6696 mL |