Clopidol (Synonyms: WR-61112)

Cat. No.: HY-B1088 Purity: 99.90%: FAQs
Data Sheet SDS COA Handling Instructions

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Clopidol (WR-61112) is an anticoccidial agent which is used as feed additive to control coccidiosis in chickens. Clopidol inhibits the sporulation of Eimeria tenella oocysts.

For research use only. We do not sell to patients.

Clopidol Chemical Structure

CAS No. : 2971-90-6

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100 mg	USD 72	In-stock	Estimated Time of Arrival: December 31
500 mg	USD 96	In-stock	Estimated Time of Arrival: December 31
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Biological Activity
Purity & Documentation
References
Customer Review

Description

Clopidol (WR-61112) is an anticoccidial agent which is used as feed additive to control coccidiosis in chickens. Clopidol inhibits the sporulation of Eimeria tenella oocysts^[1]^[2].

IC₅₀ & Target

Plasmodium

Coccidia

In Vitro

Clopidol is active against Plasmodium falciparum W2 (chloroquine-resistant) and FCR3 (atovaquone-resistant) strains in the low micromolar range^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Clopidol (31.25-93.75 mg/kg feed; p.o. for 10 d) decreases rate of oocyst sporulation of Eimeria tenella^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

192.04

Formula

C₇H₇Cl₂NO

CAS No.

2971-90-6

Appearance

Solid

Color

White to off-white

SMILES

OC1=C(Cl)C(C)=NC(C)=C1Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	2 years
	-20°C	1 year

Solvent & Solubility

In Vitro:

0.1 M NaOH : 26 mg/mL (135.39 mM; ultrasonic and adjust pH to 3 with NaOH)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.2072 mL	26.0362 mL	52.0725 mL
5 mM	1.0414 mL	5.2072 mL	10.4145 mL
10 mM	0.5207 mL	2.6036 mL	5.2072 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.90%

Select Batch:

Data Sheet (274 KB) SDS (0 KB)

COA (251 KB) RP-HPLC (248 KB)

Handling Instructions (2659 KB)

References

[1]. Pang GF, et, al. Determination of clopidol residues in chicken tissues by high-performance liquid chromatography-mass spectrometry. J Chromatogr A. 2000 Jun 16;882(1-2):85-8. [Content Brief]

[2]. Arakawa A, et, al. Effects of clopidol on sporulation and infectivity of Eimeria tenella oocysts. Vet Parasitol. 1991 Jan;38(1):55-60. [Content Brief]

[3]. Rodrigues T, et, al. Design, synthesis and structure-activity relationships of (1H-pyridin-4-ylidene)amines as potential antimalarials. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3476-80. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

0.1 M NaOH	1 mM	5.2072 mL	26.0362 mL	52.0725 mL	130.1812 mL
	5 mM	1.0414 mL	5.2072 mL	10.4145 mL	26.0362 mL
	10 mM	0.5207 mL	2.6036 mL	5.2072 mL	13.0181 mL
	15 mM	0.3471 mL	1.7357 mL	3.4715 mL	8.6787 mL
	20 mM	0.2604 mL	1.3018 mL	2.6036 mL	6.5091 mL
	25 mM	0.2083 mL	1.0414 mL	2.0829 mL	5.2072 mL
	30 mM	0.1736 mL	0.8679 mL	1.7357 mL	4.3394 mL
	40 mM	0.1302 mL	0.6509 mL	1.3018 mL	3.2545 mL
	50 mM	0.1041 mL	0.5207 mL	1.0414 mL	2.6036 mL
	60 mM	0.0868 mL	0.4339 mL	0.8679 mL	2.1697 mL
	80 mM	0.0651 mL	0.3255 mL	0.6509 mL	1.6273 mL
	100 mM	0.0521 mL	0.2604 mL	0.5207 mL	1.3018 mL

Clopidol Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Clopidol2971-90-6WR-61112WR61112WR 61112ParasiteAntibioticanticoccidialcoccidiosisInhibitorinhibitorinhibit

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