AChE-IN-51
AChE-IN-51 (compound 8C) is an orally active, non-competitive inhibitor of AChE and BChE (IC50: 84 nM, 97 nM). It also inhibits MMP-2 and amyloid Aβ1-42 aggregates (IC50: 724 nM, 302 nM). AChE-IN-51 has low cytotoxicity and in silico predicted blood-brain barrier permeability. Can be used for research on diseases such as Alzheimer's disease (AD).
For research use only. We do not sell to patients.
- Formula: C23H21OP
- Molecular Weight:344.39
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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AChE 84 nM (IC50) |
BChE 97 nM (IC50) |
MMP-2 724 nM (IC50) |
Chemical Information
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Molecular Weight 344.39
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Formula C23H21OP
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SMILES
CC(C(C=C)=P(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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