AMC-3-030
AMC-3-030 is a selective and potent dual inhibitor targeting HDAC6 and chymotrypsin-like proteasome with IC50 values of 884 and 4.17 nM. AMC-3-030 has a proliferation inhibitory effect. AMC-3-030 can reduce α-tubulin and β-actin levels. AMC-3-030 can be used for research of multiple myeloma.
For research use only. We do not sell to patients.
- CAS No.: 2926656-07-5
- Formula: C32H41BN4O7
- Molecular Weight:604.50
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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HDAC6 884 nM (IC50) |
HDAC1 >30 μM (IC50) |
α-tubulin |
AMC-3-030 has a proliferation inhibitory effect on RPMI-8226 cells (IC50 = 4.54 μM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2926656-07-5
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Molecular Weight 604.50
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Formula C32H41BN4O7
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SMILES
O=C(C1=CC=C(C(NOC(NC2=CC=CC=C2)=O)=O)C=C1)NCC(N[C@@H](CC(C)C)B3O[C@@]([C@H]4C(C)(C)[C@H](C4)C5)(C)C5O3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AMC-3-030 Related Classifications
HY-180934 Related Classifications
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