Anticancer agent 235
Anticancer agent 235 (Compound 49) is a modulator for PI3K/AKT/mTOR pathway, that promotes the generation of ROS, reduces the mitochondrial membrane potential, and thereby inhibits the proliferation of cancer cells HCT116, Caco-2, AGS and SMMC-772 with IC50 of 0.35-26.9 μM. Anticancer agent 235 arrests the cell cycle at G2/M phase, and induces apoptosis in HCT116.
For research use only. We do not sell to patients.
- CAS No.: 2411108-21-7
- Formula: C17H13ClN2O
- Molecular Weight:296.75
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 2411108-21-7
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Molecular Weight 296.75
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Formula C17H13ClN2O
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SMILES
CN1C2=NC3=CC(OC)=CC=C3C2=CC4=C1C=CC(Cl)=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)