Antitumor agent-173
Antitumor agent-173 (Compound 4b) is a prodrug of Cycloicaritin (HY-N1940). Antitumor agent-173 is a substrate for OATP2B1. Antitumor agent-173 selectively inhibits the growth of tumor Antitumor agent-173 significantly increases the oral bioavailability of Cycloicaritin and exerts good antitumor activity and safety.
For research use only. We do not sell to patients.
- Formula: C28H31NO9
- Molecular Weight:525.55
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| NIH3T3 | IC50 |
>100 μM
Compound: 4b
|
Cytotoxicity against mouse 3T3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Cytotoxicity against mouse 3T3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 38972080] |
Chemical Information
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Molecular Weight 525.55
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Formula C28H31NO9
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SMILES
COC(C=C1)=CC=C1C2=C(OC(N[C@@H](CC(C)C)C(O)=O)=O)C(C3=C(O)C=C4C(CCC(C)(C)O4)=C3O2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)