NEP108
NEP108 is a GID4 E3 ligase-based BRD4 PROTAC degrader, with its DC50 value approximately 3.8 μM. NEP108 has a strong affinity for GID4, with a KD value of 0.22 μM, and the KD value of its trimeric complex is 2.85 μM. NEP108 can be used for cancer research.
(Pink: BRD4 ligand (HY-78695); Blue: Ligands for E3 Ligase ligand (HY-D2259); Black: linker).
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 3031840-31-7
- Formel: C47H51ClN10O4S
- Molecular Weight:887.49
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Alle PROTACs Isoform-spezifische Produkte anzeigen
More
Biologische Aktivität
|
BRD4 3.8 μM (DC50) |
Chemical Information
-
CAS. Nr. 3031840-31-7
-
Molecular Weight 887.49
-
Formel C47H51ClN10O4S
-
SMILES
CC1=NN=C2[C@H](CC(NCCOCCOC3=CC4=C(C=C3)N=C([C@H]5CC[C@@H](NC(CNCC6=CC7=C(C=CC=C7)N6)=O)CC5)N4)=O)N=C(C8=CC=C(Cl)C=C8)C9=C(SC(C)=C9C)N12
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
NEP108 Related Classifications
HY-180957 Related Classifications
Powered by Bioz