PRT3645
PRT3645 (Example 20) is a CDK Inhibitor. CDK-IN-12 Inhibits CDK4/6 with IC50 values less than 20 nM.
For research use only. We do not sell to patients.
- CAS No.: 2789680-97-1
- Formula: C26H29FN6OS
- Molecular Weight:492.61
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
CDK4 <20 nM (IC50) |
CDK6 <20 nM (IC50) |
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 2789680-97-1
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Molecular Weight 492.61
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Formula C26H29FN6OS
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SMILES
O=C1C2=C(C3(CCCC3)N1C)SC(C4=C(F)C=NC(NC5=NC=C(C6CCN(CC6)C)C=C5)=N4)=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)