CDK2-IN-45
CDK2-IN-45 (Compound 8f) is a CDK2 inhibitor (IC50: 0.64 μM). CDK2-IN-45 inhibits the proliferation of DU-145 and PC-3 cell lines with IC50 of 2.20 μM and 4.17 μM, respectively. CDK2-IN-45 induces G0/G1 cell cycle arrest and apoptosis. CDK2-IN-45 can be used in prostate cancer research.
For research use only. We do not sell to patients.
- Formula: C25H16ClN5S
- Molecular Weight:453.95
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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CDK2 0.64 μM (IC50) |
Chemical Information
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Molecular Weight 453.95
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Formula C25H16ClN5S
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SMILES
ClC(C=C1)=CC=C1C2=CC=NC3=C(C(NC4=CC=CC=C4)=NN32)C5=NC6=C(S5)C=CC=C6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)