CDK2-IN-48
CDK2-IN-48 (Compound 109) is a CDK2 inhibitor with IC50 values for CDK2 and CDK1 of respectively < 0.05 and > 1 μM. CDK2-IN-48 can be used for the study of CDK2-dependent cancers.
For research use only. We do not sell to patients.
- Formula: C17H26N6O3S
- Molecular Weight:394.49
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
CDK2 < 0.05 μM (IC50) |
CDK1 > 1 μM (IC50) |
Chemical Information
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Molecular Weight 394.49
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Formula C17H26N6O3S
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SMILES
CN1C(N(C2=C1C=NC(NC3CCN(CC3)S(C)(=O)=O)=N2)C4CCCC4)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CDK2-IN-48 Related Classifications
HY-178756 Related Classifications
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