CDK7-IN-7
CDK7-IN-7 is a potent and selective CDK7 kinase inhibitor with an IC50 of <50 nM (Patent CN112661745A, compound T-01).
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 2640208-01-9
- Fòrmula: C20H20BrF3N6O2
- Peso molecular:513.31
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Descripciòn
IC50 & Target
[1]|
CDK7 <50 nM (IC50) |
In Vitro
CDK7-IN-7 shows inhibitory against MDA‑MB 231, MDA-MB453, OVCAR3, A2780, HCT-116, WiDr and Calu-6 cells (IC50 ranging from 12.21 to 144.9 nM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 2640208-01-9
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Peso molecular 513.31
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Fòrmula C20H20BrF3N6O2
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SMILES
FC(F)(C1=CN=C(N[C@H]2CCCNC2)N=C1C(C3=CC=C4NC(OC)=O)=CNC3=C4Br)F
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)