CDK7-IN-7
CDK7-IN-7 is a potent and selective CDK7 kinase inhibitor with an IC50 of <50 nM (Patent CN112661745A, compound T-01).
For research use only. We do not sell to patients.
- CAS No.: 2640208-01-9
- Formula: C20H20BrF3N6O2
- Molecular Weight:513.31
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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CDK7 <50 nM (IC50) |
CDK7-IN-7 shows inhibitory against MDA‑MB 231, MDA-MB453, OVCAR3, A2780, HCT-116, WiDr and Calu-6 cells (IC50 ranging from 12.21 to 144.9 nM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2640208-01-9
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Molecular Weight 513.31
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Formula C20H20BrF3N6O2
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SMILES
FC(F)(C1=CN=C(N[C@H]2CCCNC2)N=C1C(C3=CC=C4NC(OC)=O)=CNC3=C4Br)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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