AChE-IN-51
AChE-IN-51 (compound 8C) is an orally active, non-competitive inhibitor of AChE and BChE (IC50: 84 nM, 97 nM). It also inhibits MMP-2 and amyloid Aβ1-42 aggregates (IC50: 724 nM, 302 nM). AChE-IN-51 has low cytotoxicity and in silico predicted blood-brain barrier permeability. Can be used for research on diseases such as Alzheimer's disease (AD).
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C23H21OP
- Molecular Weight:344.39
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
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AChE 84 nM (IC50) |
BChE 97 nM (IC50) |
MMP-2 724 nM (IC50) |
Chemical Information
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Molecular Weight 344.39
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Formel C23H21OP
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SMILES
CC(C(C=C)=P(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)