CDK2-IN-27
CDK2-IN-27 (compound 1) is a potent CDK2 inhibitor with IC50 values of <10, >10-20 nM for CDK2/cyclin E1, CDK2/cyclin B1, respectively.
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- CAS. Nr.: 2927473-94-5
- Formel: C18H21N7O2
- Molecular Weight:367.41
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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- Reinheit & Dokumentation
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Help & FAQs
Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
CDK2/cyclin E1 <10 nM (IC50) |
CDK1/cyclinB1 >10-20 nM nM (IC50) |
Chemical Information
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CAS. Nr. 2927473-94-5
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Molecular Weight 367.41
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Formel C18H21N7O2
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SMILES
CC1(CC1)NC(O[C@H](CC2)C[C@H]2C3=CC(NC4=NC=C(C#N)N=C4)=NN3)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
CDK2-IN-27 Related Classifications
HY-160643 Related Classifications
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