M1-20
M1-20 is a CDK1 inhibitor. M1-20 promotes CDK1 ubiquitination by CUL4-DDB1-DCAF1 complexes and degradation through the proteasome pathway. M1-20 abolishes the formation of CDK1/CCNB1 complexes. M1-20 has significant anticancer activity of spontaneous breast cancer in FVB/N MMTV-PyVT mice model.
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- Formel: C153H269N53O43S
- Molecular Weight:3571.17
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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CDK1 |
Chemical Information
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Molecular Weight 3571.17
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Formel C153H269N53O43S
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Sequence
d{Gly-Arg-Arg-Arg-Gln-Arg-Arg-Lys-Lys-Arg-Leu-Gly-Pro-Phe-Ser-Ile-Asp-Leu-Leu-Ile-Lys-Ser-Leu-Ser-Asp-Asn-Met-Thr-Asp-Leu}
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Sequence Shortening
d{GRRRQRRKKRLGPFSIDLLIKSLSDNMTDL}
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
M1-20 Related Classifications
HY-P11028 Related Classifications
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