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Cat. No.: HY-172597

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YL-1-9

YL-1-9 is an inhibitor of the degradation of p53 by MDM2 through strong binding to the key hydrophobic pockets of MDM2. YL-1-9 induces cell cycle arrest and apoptosis in breast cancer cells.

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CAS No.: 3064304-12-4
Formule: C₂₂H₂₃F₃N₂O₃
Masse moléculaire:420.42

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

YL-1-9 Chemical Structure

CAS No.: 3064304-12-4

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

YL-1-9 is an inhibitor of the degradation of p53 by MDM2 through strong binding to the key hydrophobic pockets of MDM2. YL-1-9 induces cell cycle arrest and apoptosis in breast cancer cells^[1].

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Chemical Information

CAS No. 3064304-12-4
Masse moléculaire 420.42
Formule C₂₂H₂₃F₃N₂O₃
SMILES

O=C(NC1=CC(C(F)(F)F)=C(CN2CCC(C)CC2)C=C1)C3=CC(OCO4)=C4C=C3
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Chongyun Zhou, et al. The novel Piperine derivative YL-1-9 exhibits anti-breast Cancer effects by inducing apoptosis via the p53/p21 pathway. Bioorg Med Chem Lett. 2025 Aug 1:123:130231. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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YL-1-9

Voir tous les produits spécifiques à Isoform CDK

Activité biologique

Description

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

YL-1-9 Related Classifications

HY-172597 Related Classifications

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