CYP17A1/HDAC6-IN-1
CYP17A1/HDAC6-IN-1 (compound 12) is a potent inhibitor of CYP17A1/HDAC6, with IC50 of 0.284μM and 0.6015 μM,respectively. CYP17A1/HDAC6-IN-1 has anti-tumor activity.
For research use only. We do not sell to patients.
- CAS No.: 3047489-22-2
- Formula: C31H42N2O4
- Molecular Weight:506.68
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
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CYP17A1 0.284 μM (IC50) |
HDAC6 0.6015 μM (IC50) |
Chemical Information
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CAS No. 3047489-22-2
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Molecular Weight 506.68
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Formula C31H42N2O4
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SMILES
C[C@@]12[C@](CC=C2C3=CN=CC=C3)([H])[C@@]4([H])[C@@](CC1)([H])[C@@]5(C(C[C@H](CC5)OC(CCCCCC(NO)=O)=O)=CC4)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CYP17A1/HDAC6-IN-1 Related Classifications
HY-163359 Related Classifications
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