Deacetyltanghinin
Deacetyltanghinin is a selective inhibitor targeting Na+/K+ ATPase, acting through non-covalent binding but is highly cardiotoxic. Deacetyltanghinin inhibits Na+/K+ ATPase activity, induces cancer cell apoptosis (involving caspase pathway activation), and at the same time affect the TXA2-PGI2 balance in the rabbit heart. Deacetyltanghinin has significant anti-cancer activity and is mainly used in the research field of targeted therapy of malignant tumors such as breast cancer and lung cancer. At the same time, attention should be paid to the regulation of its cardiotoxicity.
For research use only. We do not sell to patients.
- CAS No.: 4589-95-1
- Formula: C30H44O9
- Molecular Weight:548.66
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Caspase Isoforms
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Biological Activity
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TXA2 |
Chemical Information
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CAS No. 4589-95-1
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Molecular Weight 548.66
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Formula C30H44O9
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SMILES
O[C@@]12[C@@]34[C@@](C[C@@]5([H])[C@@]([C@@]4([H])CC[C@@]1([C@@H](C(CO6)=CC6=O)CC2)C)(CC[C@@H](C5)O[C@H]7[C@H]([C@@H]([C@H]([C@@H](O7)C)O)OC)O)C)([H])O3
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)