DB0662
Based on 1 Customer Validation
DB0662 is a multi-target kinase-directed PROTAC degrader, targeting kinases including PTK2B, MAPK9, BLK, CSK, LIMK1, etc.
(Pink: Ligands for Target Protein for PROTAC ligand (HY-176367); Blue: Cereblon ligand (HY-14658); Black: linker).
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 99.66%
- No. CAS: 2769753-51-5
- Fòrmula: C47H44F3N11O7
- Peso molecular:931.92
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
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Actividad biológica
Chemical Information
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No. CAS 2769753-51-5
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Appearance Solid
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Peso molecular 931.92
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Fòrmula C47H44F3N11O7
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Color Light yellow to yellow
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SMILES
O=C(C1=CC=CC(C(F)(F)F)=C1)NC2=CC=C(C)C(N3C(N(C)C4=NC(NC5=CN=C(N6CCN(CCCOC7=CC=CC(C(N8C9C(NC(CC9)=O)=O)=O)=C7C8=O)CC6)C=C5)=NC=C4C3)=O)=C2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
DMSO : 50 mg/mL (53.65 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (267 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.0731 mL | 5.3653 mL | 10.7305 mL | 26.8263 mL |
| 5 mM | 0.2146 mL | 1.0731 mL | 2.1461 mL | 5.3653 mL | |
| 10 mM | 0.1073 mL | 0.5365 mL | 1.0731 mL | 2.6826 mL | |
| 15 mM | 0.0715 mL | 0.3577 mL | 0.7154 mL | 1.7884 mL | |
| 20 mM | 0.0537 mL | 0.2683 mL | 0.5365 mL | 1.3413 mL | |
| 25 mM | 0.0429 mL | 0.2146 mL | 0.4292 mL | 1.0731 mL | |
| 30 mM | 0.0358 mL | 0.1788 mL | 0.3577 mL | 0.8942 mL | |
| 40 mM | 0.0268 mL | 0.1341 mL | 0.2683 mL | 0.6707 mL | |
| 50 mM | 0.0215 mL | 0.1073 mL | 0.2146 mL | 0.5365 mL |
DB0662 Related Classifications
HY-148066 Related Classifications
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