JHD205
JHD205 is a CDK4/6 inhibitor that induces apoptosis and DNA damage. JHD205 inhibits DNA repair by upregulating Caspase3 and p-H2AX. JHD205 has superior potency to Abemaciclib (HY-16297A) in a xenograft chick embryo breast cancer model..
Para uso exclusivo en investigación. No vendemos a pacientes.
- Fòrmula: C32H40F2N8O
- Peso molecular:590.71
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Descripciòn
Chemical Information
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Peso molecular 590.71
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Fòrmula C32H40F2N8O
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SMILES
COC1=CC(N2CCC(CC2)N3CCN(CC3)C)=CC=C1NC4=NC(C5=CC(F)=C6C(N(C(C)=N6)C(C)C)=C5)=C(C=N4)F
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)