M1-20
M1-20 is a CDK1 inhibitor. M1-20 promotes CDK1 ubiquitination by CUL4-DDB1-DCAF1 complexes and degradation through the proteasome pathway. M1-20 abolishes the formation of CDK1/CCNB1 complexes. M1-20 has significant anticancer activity of spontaneous breast cancer in FVB/N MMTV-PyVT mice model.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Fòrmula: C153H269N53O43S
- Peso molecular:3571.17
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Help & FAQs
Actividad biológica
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CDK1 |
Chemical Information
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Peso molecular 3571.17
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Fòrmula C153H269N53O43S
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Sequence
d{Gly-Arg-Arg-Arg-Gln-Arg-Arg-Lys-Lys-Arg-Leu-Gly-Pro-Phe-Ser-Ile-Asp-Leu-Leu-Ile-Lys-Ser-Leu-Ser-Asp-Asn-Met-Thr-Asp-Leu}
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Sequence Shortening
d{GRRRQRRKKRLGPFSIDLLIKSLSDNMTDL}
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
M1-20 Related Classifications
HY-P11028 Related Classifications
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