Icam1 - intercellular adhesion molecule 1 Gene

Also Known as CD54; Ly-47; Icam-1; MALA-2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 15894

Summary

This gene encodes an integral membrane protein that binds leukocyte adhesion protein LFA-1. It participates in the innate immune response. [provided by RefSeq, Aug 2016]

Icam1 Products (1)

mRNA Protein Name
NM_010493.3 NP_034623.1 intercellular adhesion molecule 1 precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within T cell antigen processing and presentation IDA
IDA: Inferred from direct assay
2479693 MGI
acts upstream of or within T cell extravasation IMP
IMP: Inferred from mutant phenotype
17344467 MGI
acts upstream of or within cell adhesion IDA
IDA: Inferred from direct assay
10528208 MGI
acts upstream of or within cell adhesion mediated by integrin IDA
IDA: Inferred from direct assay
10601245 MGI
acts upstream of or within cellular response to glucose stimulus IDA
IDA: Inferred from direct assay
17670746 MGI
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: Inferred from expression pattern
20439489 MGI
acts upstream of or within leukocyte cell-cell adhesion IMP
IMP: Inferred from mutant phenotype
8562500 MGI
acts upstream of or within regulation of ruffle assembly IDA
IDA: Inferred from direct assay
23372835 MGI
Cellular Component GO Annotation Evidence References Source
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
16973387 MGI
located in immunological synapse IDA
IDA: Inferred from direct assay
14973438 MGI
colocalizes with membrane raft IDA
IDA: Inferred from direct assay
12763482 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

intercellular adhesion molecule 1

  • myD10

Recombinant Icam1 Proteins

Cat. No. Product Name Accession Purity
HY-P73112 ICAM-1/CD54 Protein, Mouse (HEK293, His-Fc) P13597 (Q28-N485) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P73113 ICAM-1/CD54 Protein, Mouse (HEK293, His) P13597 (Q28-N485) ≥ 95%, as determined by reducing SDS-PAGE.

Icam1 Antibodies

Cat. No. Product Name Application Reactivity
HY-P89817 ICAM-1/CD54 Antibody (YA9161) WB, ICC/IF, IF-Tissue, IHC-P, FC mouse, rat

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-19344 Lifitegrast Antagonist 99.29% Unkown
HY-19344A Lifitegrast sodium Inhibitor 99.20% Unkown
HY-B0665 Fibrin / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-108831 Natalizumab Inhibitor 99.10% Unkown

Clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-145728 Alicaforsen Inhibitor / Phase 3
HY-167874 ASP-8731 Inhibitor 98.42% Phase 1
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99473 Bersanlimab Inhibitor 99.85% Phase 2

Pre-clinical Phase

Bioactive Molecules (47)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-N0637 Eriodictyol Inhibitor 99.55% Unkown
HY-33037 Phenazine-1-carboxylic acid Inhibitor 99.97% Unkown
HY-100226 A-205804 Inhibitor 98.96% Unkown
HY-15701 Leukadherin-1 Agonist 98.0% Unkown
HY-112868B ABH hydrochloride 99.90% Unkown
HY-P1110 AF12198 Inhibitor 99.92% Unkown
HY-110117 BIRT 377 Inhibitor 99.82% Unkown
HY-N2464 Maltotetraose Inhibitor 99.88% Unkown
HY-U00003 ICAM-1-IN-1 Inhibitor 99.73% Unkown
HY-N0602 Ginsenoside Rg2 Inhibitor 98.71% Unkown
HY-N2110 Phellopterin 99.94% Unkown
HY-107587 A-286982 Inhibitor 98.12% Unkown
HY-N1353 Rhamnocitrin Inhibitor 99.67% Unkown
HY-125740 Malvidin-3-glucoside chloride Inhibitor 99.87% Unkown
HY-B2162D Chondroitin sulfate (from chicken) Inhibitor 99.61% Unkown
HY-N0637A (±)-Eriodictyol Inhibitor 99.9% Unkown
HY-W588250 Surfactin C1 Antagonist 99.31% Unkown
HY-145728B (R/S)-Alicaforsen Inhibitor 99.27% Unkown
HY-P2508 MUC1, mucin core 98.84% Unkown
HY-10596 BMS-688521 Inhibitor 98.62% Unkown
HY-N12717 Casuarinin 98.24% Unkown
HY-101961 Tyrphostin AG 1288 Inhibitor 98.68% Unkown
HY-110086 RWJ 50271 Inhibitor 99.23% Unkown
HY-W013557 3-Hydroxyxanthone Inhibitor 98.38% Unkown
HY-P5767 Fibrinogen γ-chain (117-133) Inhibitor 99.88% Unkown
HY-W241255 2-Aminoindan-2-carboxylic acid / Unkown
HY-13412 Cariporide (mesilate) Modulator / Unkown
HY-145728A Alicaforsen sodium Inhibitor / Unkown
HY-122192 ICAM-1988 Antagonist / Unkown
HY-143243 Antioxidant agent-5 Inhibitor / Unkown
HY-180939 LFA-1-IN-2 Inhibitor / Unkown
HY-186198 FTS-MOM Inhibitor / Unkown
HY-N0602R Ginsenoside Rg2 (Standard) Inhibitor / Unkown
HY-N11996 Aloenin aglycone / Unkown
HY-N14915 Adxanthromycin A Inhibitor / Unkown
HY-N15519 Crocatin B Inhibitor / Unkown
HY-N4275 Oleaside A / Unkown
HY-P11799 cLABL Ligand / Unkown
HY-RS06512 ICAM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-112868A ABH Inhibitor / Unkown
HY-183448 ETMTC / Unkown
HY-183516 Osteoprotegerin / Unkown
HY-19344S Lifitegrast-d4 / Unkown
HY-19344S1 Lifitegrast-d6 / Unkown
HY-19344S2 Lifitegrast-d4-1 Antagonist / Unkown
HY-RS16658 Icam1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23093 Icam1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (10)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-108831A Natalizumab (Anti-CD49d) Inhibitor 99.71% Unkown
HY-P99127 Anti-Mouse CD54 Antibody (YN1/1.7.4) Inhibitor 95.00% Unkown
HY-P99336 Enlimomab Inhibitor 95.00% Unkown
HY-P990857 Anti-CD54/ICAM-1 Antibody (R6-5-D6) Inhibitor / Unkown
HY-P991250 MSH-TP15e Inhibitor / Unkown
HY-P991591 MOR101 Inhibitor / Unkown
HY-P991819 Anti-Mouse ICAM-1 Antibody (BE29G1) Inhibitor / Unkown
HY-P992053 Anti-CD11a Antibody (MHM24) Inhibitor / Unkown
HY-P992200 Anti-CD146 Antibody (AA98) / Unkown
HY-P992413 MOR102 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Icam1 NCBI NCBI:3383